About: Application of a rapid and integrated analysis system (RIAS) as a high-throughput processing tool for in vitro ADME samples by liquid chromatography/tandem mass spectrometry

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About: Application of a rapid and integrated analysis system (RIAS) as a high-throughput processing tool for in vitro ADME samples by liquid chromatography/tandem mass spectrometry Goto Sponge NotDistinct Permalink

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scientific article published on 18 February 2011

Attributes	Values
rdf:type	Item
description	videnskabelig artikel (da) article científic (ca) articolo scientifico (it) artigo científico (pt) bilimsel makale (tr) vedecký článok (sk) vetenskaplig artikel (sv) vědecký článek (cs) wetenschappelijk artikel (nl) wissenschaftlicher Artikel (de) научни чланак (sr) article scientifique (fr) artículu científicu espublizáu en 2011 (ast) наукова стаття, опублікована в лютому 2011 (uk) scientific article published on 18 February 2011 (en) مقالة علمية نشرت في 18 فبراير 2011 (ar)
publication date	wds:Q37845031-7CC996C2-D283-4A84-BAE4-2A696BFC379E
publication date	2011-02-18 00:00:00Z (xsd:dateTime)
cites work	wds:Q37845031-42A9F1E2-35EA-4D58-BCD6-03E2DB488DC0 wds:Q37845031-5DA410FF-133F-4B8D-B0E3-DD820EAC7BBC wds:Q37845031-6A4FC419-7F35-4F99-8538-5DAD9DACA637 wds:Q37845031-7444B6B6-D895-4BB1-8D09-3D48BC2DD9FA wds:Q37845031-8C8277FB-2E6C-419C-83FD-B56C3C42F444 wds:Q37845031-8E1EEE12-106A-4DEC-8D96-C6A142D49CD7 wds:Q37845031-9C33D186-C135-47BC-ABD9-1E6E316DA010 wds:Q37845031-A27BFD89-C9DA-4F1F-B701-1F5AFC9A69FF wds:Q37845031-DAE14059-99BD-49CD-B094-87A9D21D2BB4 wds:Q37845031-DE6B0AA6-66D9-44C0-9DCB-F9E2DFCF12C5 wds:Q37845031-DEDFE908-9B1B-4926-8F75-8F1044DC788B wds:Q37845031-F54ADB12-6654-4AA6-B14B-C2C2D54BE780
cites work	Bioanalysis without sample cleanup or chromatography: the evaluation and initial implementation of direct analysis in real time ionization mass spectrometry for the quantification of drugs in biological matrixes Perspectives on bioanalytical mass spectrometry and automation in drug discovery Extending matrix-assisted laser desorption/ionization triple quadrupole mass spectrometry enzyme screening assays to targets with small molecule substrates Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells In vitro interaction cocktail assay for nine major cytochrome P450 enzymes with 13 probe reactions and a single LC/MSMS run: analytical validation and testing with monoclonal anti-CYP antibodies A high-capacity LC/MS system for the bioanalysis of samples generated from plate-based metabolic screening Optimization of a higher throughput microsomal stability screening assay for profiling drug discovery candidates. Applications of high-throughput ADME in drug discovery A high throughput metabolic stability screening workflow with automated assessment of data quality in pharmaceutical industry Increasing high-throughput discovery bioanalysis using automated selected reaction monitoring compound optimization, ultra-high-pressure liquid chromatography, and single-step sample preparation workflows Development of a high-throughput online solid-phase extraction/tandem mass spectrometry method for cytochrome P450 inhibition screening A high-throughput bioanalytical platform using automated infusion for tandem mass spectrometric method optimization and its application in a metabolic stability screen.
author name string	wds:Q37845031-089CD5DC-D900-4787-A0FD-92384F50FBAD wds:Q37845031-4253E804-93E2-4050-9A30-F43C9006280D wds:Q37845031-43EE2872-006B-41B4-8448-E58E26B350E4 wds:Q37845031-4F45FCD5-5619-49AB-87D1-72C231A509D5 wds:Q37845031-A2A84332-1205-4BE9-86E5-F0BA0C367399
author name string	Roderich D Süssmuth Andreas H Luippold Beate Krüger Thomas Arnhold Wolfgang Jörg
rdfs:label	Application of a rapid and integrated analysis system (nl) Application of a rapid and integrated analysis system (RIAS) as a high-throughput processing tool for in vitro ADME samples by liquid chromatography/tandem mass spectrometry (en) Application of a rapid and integrated analysis system (RIAS) as a high-throughput processing tool for in vitro ADME samples by liquid chromatography/tandem mass spectrometry (ast)
skos:prefLabel	Application of a rapid and integrated analysis system (nl) Application of a rapid and integrated analysis system (RIAS) as a high-throughput processing tool for in vitro ADME samples by liquid chromatography/tandem mass spectrometry (en) Application of a rapid and integrated analysis system (RIAS) as a high-throughput processing tool for in vitro ADME samples by liquid chromatography/tandem mass spectrometry (ast)
name	Application of a rapid and integrated analysis system (nl) Application of a rapid and integrated analysis system (RIAS) as a high-throughput processing tool for in vitro ADME samples by liquid chromatography/tandem mass spectrometry (en) Application of a rapid and integrated analysis system (RIAS) as a high-throughput processing tool for in vitro ADME samples by liquid chromatography/tandem mass spectrometry (ast)
title	wds:Q37845031-843E5F3E-3A05-4AD1-BF7A-6CB0F8764AAF
title	Application of a rapid and integrated analysis system (RIAS) as a high-throughput processing tool for in vitro ADME samples by liquid chromatography/tandem mass spectrometry (en)
page(s)	wds:Q37845031-5BA8A3AC-EA46-45FC-8281-5219BCF1766F
page(s)	370-377
instance of	wds:Q37845031-0C05C811-A278-442F-89C3-56697A4A9180
instance of	scholarly article
PubMed ID	wds:Q37845031-8F3EF51B-A38D-4375-AA4C-C4E942673B92
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/21335598
PubMed ID	21335598
published in	wds:Q37845031-CC9D733E-ECD0-44A6-9CE4-10823D18B686
published in	Journal of Biomolecular Screening
issue	wds:Q37845031-5E96961D-243D-45BB-B84F-92270B8493F4
volume	wds:Q37845031-C5DA2041-17C2-415C-8528-27A7B3897294
issue	3
volume	16
DOI	wds:Q37845031-16049B21-21D5-4EA0-A4F1-4503C28676DF
DOI	http://dx.doi.org/10.1177/1087057110397358
DOI	10.1177/1087057110397358
ResearchGate publication ID	wds:Q37845031-02ED622A-0E40-4723-B582-9A427AF62035
ResearchGate publication ID	49849830
describes a project that uses	wds:Q37845031-2B63C0DC-D0A6-46A6-9ACE-CA85540E2EBE
describes a project that uses	liquid chromatography-tandem mass spectrometry
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q37845031
is cites work of	A simplified approach to predict CYP3A-mediated drug-drug interactions at early drug discovery: validation with clinical data In vitro ADME profiling using high-throughput rapidfire mass spectrometry: cytochrome p450 inhibition and metabolic stability assays Standardized workflows for increasing efficiency and productivity in discovery stage bioanalysis Recent development in software and automation tools for high-throughput discovery bioanalysis Development of a high-speed, multiplexed sample-delivery instrument for LC-MS/MS bioanalysis. SPE-MS analysis of absorption, distribution, metabolism and excretion assays: a tool to increase throughput and steamline workflow A Comparison of LC-MS/MS and a Fully Integrated Autosampler/Solid-Phase Extraction System for the Analysis of Protein Binding Samples Characterisation of the properties of a selective, orally bioavailable autotaxin inhibitor in preclinical models of advanced stages of liver fibrosis. Selective and Potent CDK8/19 Inhibitors Enhance NK-Cell Activity and Promote Tumor Surveillance Assessment of CYP3A-mediated drug-drug interaction potential for victim drugs using an in vivo rat model Bioanalysis in oncology drug discovery Beyond classical derivatization: analyte 'derivatives' in the bioanalysis of endogenous and exogenous compounds Recent developments in software tools for high-throughput in vitro ADME support with high-resolution MS. Development of a high-performance, enterprise-level, multimode LC-MS/MS autosampler for drug discovery. Advances in glycosaminoglycan detection

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