About: Mutation of a conserved serine in TM4 of opioid receptors confers full agonistic properties to classical antagonists

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About: Mutation of a conserved serine in TM4 of opioid receptors confers full agonistic properties to classical antagonists Goto Sponge NotDistinct Permalink

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scientific article published on June 1996

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rdf:type	Item
description	videnskabelig artikel (da) article científic (ca) articolo scientifico (it) artigo científico (pt) bilimsel makale (tr) vedecký článok (sk) vetenskaplig artikel (sv) vědecký článek (cs) wetenschappelijk artikel (nl) wissenschaftlicher Artikel (de) научни чланак (sr) article scientifique (fr) artículu científicu espublizáu en 1996 (ast) наукова стаття, опублікована в червні 1996 (uk) 1996年學術文章 (zh) مقالة علمية نشرت في يونيو 1996 (ar) scientific article published on June 1996 (en)
publication date	wds:Q37550895-57D87BF1-AD40-42A2-ADEC-A6C4269C0A4A
publication date	1996-06-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q37550895-D4AF3A22-2D56-46D2-A5E8-B5A95DDD1634
language of work or name	English
cites work	wds:Q37550895-016B7CBA-D1AD-4BFE-B5DC-607BD64FAFB2 wds:Q37550895-067C80FC-400E-47A6-810F-770B6A53DE77 wds:Q37550895-07C684A3-9BFC-4574-BF6A-03EE42B0F274 wds:Q37550895-0D547CDA-9CEB-4074-BD31-FFF87AAF553F wds:Q37550895-11A1343C-914E-40B1-BF60-F4F2B7642010 wds:Q37550895-2BF59968-F1CE-400D-AA66-7FC2D875BD08 wds:Q37550895-380AAF7B-F6D6-4B46-9623-42EC5968EE7A wds:Q37550895-3A51B49B-8CD7-41E9-B5E2-3B2B3E595A31 wds:Q37550895-443F4A61-672C-4C14-A1A3-76803D4F786E wds:Q37550895-54B922D0-29D8-4215-B105-DA9C09B9F980 wds:Q37550895-54C04084-2E6F-414A-9ED1-E5AC4C5B0671 wds:Q37550895-553DADF9-CB21-4654-8E9C-DD0E01D2C7F5 wds:Q37550895-56C65002-7284-492B-BC74-2C265F1A07F8 wds:Q37550895-59B45AE4-491C-465A-9812-79EA66AAEA02 wds:Q37550895-5A4B39BD-FE7F-4B7E-BBF1-8CC3BD3AC05B wds:Q37550895-661C3E7D-2EC0-471D-A28B-DB1E003F6242 wds:Q37550895-85DA57B3-30FE-4687-ABCE-A2665843CA97 wds:Q37550895-86421C79-2ED3-4C42-ABF7-ED1BF6BF2129 wds:Q37550895-8699441E-A7D9-49FB-AD72-08B8C3DBA1B4 wds:Q37550895-899A5FC2-1F26-4A18-954F-13939ED7E559 wds:Q37550895-90A2D19E-3DDD-4327-81CF-5E183F84CC25 wds:Q37550895-99B7536F-7864-4D5F-B8EF-5BD4FE55396F wds:Q37550895-9E9D8333-AA52-4CE9-B59C-A3FA4C7A5521 wds:Q37550895-9FE9A265-6462-4500-8638-3BAB9331C2FB wds:Q37550895-ABEA14CB-6859-4CB4-A18E-0F3EB4C4FF72 wds:Q37550895-B8224516-C4B8-435B-AA0C-833223955F1F wds:Q37550895-BA5C5168-E1BD-4966-B65F-74771048F436 wds:Q37550895-BD1FAF96-95BA-4F6B-B908-41BC192B604B wds:Q37550895-CC7256CC-8CC3-47EF-8737-97929D335F8F wds:Q37550895-E165B3A1-F9F6-40DC-BFDF-02BF1115172B wds:Q37550895-E2AFAA9A-AF07-4BF9-82E6-B5D71E4DB8B1 wds:Q37550895-E7881C9E-CFF3-42B5-AFC5-A24B02024367 wds:Q37550895-F79206D9-BC32-41E0-BCB0-433B0CDE7AE4
cites work	Molecular cloning and functional expression of a mu-opioid receptor from rat brain. Efficacy and tolerance of narcotic analgesics at the mu opioid receptor in differentiated human neuroblastoma cells Kappa-opioid receptors couple to inwardly rectifying potassium channels when coexpressed by Xenopus oocytes Cloning and pharmacological characterization of a rat kappa opioid receptor LIGAND: A versatile computerized approach for characterization of ligand-binding systems Mu and delta receptors belong to a family of receptors that are coupled to potassium channels Morphine receptors as regulators of adenylate cyclase activity Primary structures and expression from cDNAs of rat opioid receptor delta- and mu-subtypes. The GTP-binding protein, Go, regulates neuronal calcium channels Atrial G protein-activated K+ channel: expression cloning and molecular properties Cloning of a delta opioid receptor by functional expression Cloning and functional comparison of kappa and delta opioid receptors from mouse brain The delta-opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterization Calcium phosphate-mediated gene transfer: a highly efficient transfection system for stably transforming cells with plasmid DNA. Protein measurement with the Folin phenol reagent -mu opiate receptor. Charged transmembrane domain amino acids are critical for agonist recognition and intrinsic activity A chimeric study of the molecular basis of affinity and selectivity of the kappa and the delta opioid receptors. Potential role of extracellular domains Simultaneous coupling of alpha 2-adrenergic receptors to two G-proteins with opposing effects. Subtype-selective coupling of alpha 2C10, alpha 2C4, and alpha 2C2 adrenergic receptors to Gi and Gs Opioids activate both an inward rectifier and a novel voltage-gated potassium conductance in the hippocampal formation Expression of the mu-opioid receptor in CHO cells: ability of mu-opioid ligands to promote alpha-azidoanilido[32P]GTP labeling of multiple G protein alpha subunits. Functional expression of adrenergic and opioid receptors in Xenopus oocytes: interaction between alpha 2- and beta 2-adrenergic receptors DAMGO, a mu-opioid receptor selective ligand, distinguishes between mu-and kappa-opioid receptors at a different region from that for the distinction between mu- and delta-opioid receptors Location of regions of the opioid receptor involved in selective agonist binding Opiate receptor down-regulation and desensitization in neuroblastoma X glioma NG108-15 hybrid cells are two separate cellular adaptation processes Cyclic somatostatin octapeptide analogues with high affinity and selectivity toward mu opioid receptors Dual excitatory and inhibitory effects of opioids on intracellular calcium in neuroblastoma x glioma hybrid NG108-15 cells Improved two-step method for the assay of adenylate and guanylate cyclase Neuroblastoma Neuro2A cells stably expressing a cloned mu-opioid receptor: a specific cellular model to study acute and chronic effects of morphine. A single residue, aspartic acid 95, in the delta opioid receptor specifies selective high affinity agonist binding. DAMGO, a mu-opioid receptor selective agonist, distinguishes between mu- and delta-opioid receptors around their first extracellular loops. Analysis of delta-opioid receptor activities stably expressed in CHO cell lines: function of receptor density? Ca2+ channel and adenylyl cyclase modulation by cloned mu-opioid receptors in GH3 cells. The third extracellular loop of the mu opioid receptor is important for agonist selectivity.
author name string	wds:Q37550895-01AB38D7-B5F7-441D-8F38-976389D4A980 wds:Q37550895-10E3840C-9EF8-487D-B789-B0D6ED02D443 wds:Q37550895-1162CA42-2F8E-4AE1-B7B6-398FE93B0A0C wds:Q37550895-4E8EEA90-A1F9-4648-9A23-4A7F3B702FFF wds:Q37550895-633C1ADF-A3C2-4028-B3DA-664FF9876651 wds:Q37550895-A72B8D44-D4CD-4DAB-8418-FC3C44A1EA1B wds:Q37550895-B5BC84EE-C7EF-45D8-9AA8-5C818EBF4845 wds:Q37550895-DB92010A-0EA5-4A77-AB9F-320570143136
author name string	X H Zhang H H Loh P Y Law P L Prather

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