About: Activation of the Raf-1/MAP kinase cascade is not sufficient for Ras transformation of RIE-1 epithelial cells

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About: Activation of the Raf-1/MAP kinase cascade is not sufficient for Ras transformation of RIE-1 epithelial cells Goto Sponge NotDistinct Permalink

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scientific article published on July 1996

Attributes	Values
rdf:type	Item
description	videnskabelig artikel (da) article científic (ca) articolo scientifico (it) artigo científico (pt) bilimsel makale (tr) vedecký článok (sk) vetenskaplig artikel (sv) vědecký článek (cs) wetenschappelijk artikel (nl) wissenschaftlicher Artikel (de) научни чланак (sr) article scientifique (fr) artículu científicu espublizáu en 1996 (ast) наукова стаття, опублікована в липні 1996 (uk) 1996年學術文章 (zh) مقالة علمية نشرت في يوليو 1996 (ar) scientific article published on July 1996 (en)
publication date	wds:Q37475615-2790821C-FC1A-4A62-98C3-4883AD66A265
publication date	1996-07-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q37475615-7F864FA8-CB4D-4AAF-A85D-FD204FA55CB0
language of work or name	English
cites work	wds:Q37475615-0D6F9B07-71EE-4904-80D4-16AE89D351F2 wds:Q37475615-0FCC10AF-03FF-4BED-9378-DDB2AACDE488 wds:Q37475615-208410A1-9E92-4720-B1C5-309E9AC2484D wds:Q37475615-27EBA6C4-20B1-4D89-939D-33063C886F6B wds:Q37475615-2E0C5078-2C3A-4893-94B0-4677C928A90C wds:Q37475615-5EC5F635-AD94-421D-B194-DDF0FB8E477D wds:Q37475615-654771F5-325F-4F0F-B375-8A20E856DEF3 wds:Q37475615-672E04BA-ADE1-44B9-AFF6-679210697D82 wds:Q37475615-739DC151-BD0A-468D-8D19-DAD3810BE689 wds:Q37475615-76A780BC-32FA-48CE-9ED9-0B93C0A81ABF wds:Q37475615-86F5A5E1-F638-4D48-BF1A-E177E400F794 wds:Q37475615-89769525-963D-4033-A81E-687D5681DC61 wds:Q37475615-93C13465-FDF8-4994-90A1-45FF51E608AE wds:Q37475615-9F6ECBF8-D12A-4F4A-8797-CCE0A78D6FFA wds:Q37475615-A0A207B2-B760-414B-9F71-9CC9571F64A0 wds:Q37475615-B3CDCFC6-F67E-4B19-87C6-60782DA59F12 wds:Q37475615-BA2232E2-7C0C-4B25-B5CF-F5A32828BBE4 wds:Q37475615-D8851C11-3E27-4732-99AE-2B58339B5316 wds:Q37475615-DA97622D-67F7-49F2-A67F-11FC1132D0F2 wds:Q37475615-DD14E83E-3264-4810-ACC9-F934ECF730EE wds:Q37475615-DE92E202-1FBA-4409-BD87-8732ED9C2945 wds:Q37475615-E634A7E9-830D-4E15-9978-5B01472523B8 wds:Q37475615-E94C6A12-32EA-48FC-BE22-E932F279B82C wds:Q37475615-F0207316-4219-4493-A25F-C47AC06F0F72 wds:Q37475615-F1624B2D-4278-4380-BD93-5E630A00B307 wds:Q37475615-F1FD738A-2D0C-4FDF-BC1B-12FE18D83AC2 wds:Q37475615-F28719B3-147D-44C2-B34A-A3941FD6A49C wds:Q37475615-F3204A22-E701-407C-8A70-2261E8A49748 wds:Q37475615-F4BCC764-A7A7-4AC3-BF35-22D9E28E5B01 wds:Q37475615-F564D4A5-824D-410A-9551-A947379FDE3B wds:Q37475615-F60A5B5B-0C89-4A2C-A190-1B340E31231D wds:Q37475615-F84260F6-63C4-4A3A-A9FB-474FF5E51A89
cites work	An essential role for Rac in Ras transformation Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane Biological assays for Ras transformation A biochemical function for ras--at last Activation of Raf as a result of recruitment to the plasma membrane Phosphatidylinositol-3-OH kinase as a direct target of Ras Identification of the guanine nucleotide dissociation stimulator for Ral as a putative effector molecule of R-ras, H-ras, K-ras, and Rap Activated Ras interacts with the Ral guanine nucleotide dissociation stimulator Guanine nucleotide exchange factors: activators of the Ras superfamily of proteins Cooperative interaction of S. pombe proteins required for mating and morphogenesis. Two distinct Raf domains mediate interaction with Ras ralGDS family members interact with the effector loop of ras p21. Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells Transformation of mammalian cells by constitutively active MAP kinase kinase Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation Multiple Ras functions can contribute to mammalian cell transformation Activation of the cellular proto-oncogene product p21Ras by addition of a myristylation signal The GTPase superfamily: conserved structure and molecular mechanism [29] Assay and expression of mitogen-activated protein kinase, MAP kinase kinase, and Raf Raf-1 protein kinase is required for growth of induced NIH/3T3 cells The Ras signal transduction pathway 14-3-3: modulators of signaling proteins? rasH mutants deficient in GTP binding Critical role of Rho in cell transformation by oncogenic Ras. Definition of the human raf amino-terminal regulatory region by deletion mutagenesis Epidermal growth factor promotes the chemotactic migration of cultured rat intestinal epithelial cells Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation Pathways of Ras function: connections to the actin cytoskeleton. Characterization of an epithelioid cell line derived from rat small intestine: Demonstration of cytokeratin filaments Mitogen-activated protein kinase/extracellular signal-regulated protein kinase activation by oncogenes, serum, and 12-O-tetradecanoylphorbol-13-acetate requires Raf and is necessary for transformation Oncogenic Ras activates c-Jun via a separate pathway from the activation of extracellular signal-regulated kinases Role of transforming growth factor alpha (TGF-alpha) in the transformation of ras-transfected rat intestinal epithelial cells.
author name string	wds:Q37475615-1F031455-C539-4D24-BC76-D5826E3538FF wds:Q37475615-6800127A-EEAF-417E-B486-69E04523C90B wds:Q37475615-AC1F905B-82DD-4A47-92FE-6074773C41FB wds:Q37475615-EDF6B086-EB9C-4EB3-878F-BA1BCF7D6809 wds:Q37475615-F2A7CFAA-F8B1-4FA2-8FCD-C269C7C86021
author name string	C J Der R J Coffey G J Clark L M Gangarosa S M Oldham
rdfs:label	Activation of the Raf-1/MAP kinase cascade is not sufficient for Ras transformation of RIE-1 epithelial cells (en) Activation of the Raf-1/MAP kinase cascade is not sufficient for Ras transformation of RIE-1 epithelial cells (nl) Activation of the Raf-1/MAP kinase cascade is not sufficient for Ras transformation of RIE-1 epithelial cells (ast)
skos:prefLabel	Activation of the Raf-1/MAP kinase cascade is not sufficient for Ras transformation of RIE-1 epithelial cells (en)

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