About: The influence of the multi-basic cleavage site of the H5 hemagglutinin on the attenuation, immunogenicity and efficacy of a live attenuated influenza A H5N1 cold-adapted vaccine virus

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About: The influence of the multi-basic cleavage site of the H5 hemagglutinin on the attenuation, immunogenicity and efficacy of a live attenuated influenza A H5N1 cold-adapted vaccine virus Goto Sponge NotDistinct Permalink

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scientific article published on 14 October 2009

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rdf:type	Item
description	videnskabelig artikel (da) article científic (ca) articolo scientifico (it) artigo científico (pt) bilimsel makale (tr) vedecký článok (sk) vetenskaplig artikel (sv) vědecký článek (cs) wetenschappelijk artikel (nl) wissenschaftlicher Artikel (de) научни чланак (sr) article scientifique (fr) artículu científicu espublizáu en 2009 (ast) наукова стаття, опублікована в жовтні 2009 (uk) مقالة علمية نشرت في 14 أكتوبر 2009 (ar) scientific article published on 14 October 2009 (en)
publication date	wds:Q37456446-A6792987-7195-473A-9524-812BCBFEFC36
publication date	2009-10-14 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q37456446-FE65AB74-A37D-4826-BD12-9F2C974532CD
language of work or name	English
cites work	wds:Q37456446-0EA3644B-740B-4A8D-A2AF-F135A065A07F wds:Q37456446-10F75597-2523-48A3-8601-B8682812149A wds:Q37456446-13C12A16-1E48-419D-AB77-439C3C48675B wds:Q37456446-1838D656-8411-4632-B5D7-B827E49E64E6 wds:Q37456446-34E5971E-BB36-494A-A36D-054E2456A6C1 wds:Q37456446-36CF3E68-21DF-45BB-8436-54BA3A3CFA5A wds:Q37456446-3D5B31F8-D704-4924-949A-97FFE89CCC30 wds:Q37456446-40AF59B9-D179-4A96-BC9A-DB55EC40A883 wds:Q37456446-42032025-3EC1-406B-B829-BE21A8099614 wds:Q37456446-5AB96CCB-1506-42F4-A7CF-0CD8D07A53E3 wds:Q37456446-6B41CCCA-3C19-4B35-B3DC-73C2E8F1171E wds:Q37456446-6ED86C3D-E422-4097-944C-E584FFC34309 wds:Q37456446-6F93A77D-783D-4535-8631-8B149F2B93B6 wds:Q37456446-733A694F-C79F-4C26-BF55-C4EBDE9D9E3A wds:Q37456446-77D5DB4C-D9A1-4EB3-A142-2BF9052A3F58 wds:Q37456446-7A2CE534-B81D-4E62-AEE5-E8DDEA1B03F7 wds:Q37456446-7AA7C84A-1E04-46D0-8BFB-482255ED7E25 wds:Q37456446-8CFB181A-769B-4E2E-ABB0-F961BAB01A8A wds:Q37456446-A2B3A018-102B-4001-85E2-E0FB836A0E74 wds:Q37456446-AECBF158-EB87-479B-9A38-ADDE762B7DF5 wds:Q37456446-B9E07D12-222B-4000-B98D-168162627B27 wds:Q37456446-BA0C81EA-9FB4-4CAB-A451-7C8CF634A833 wds:Q37456446-C0E0448C-11D5-4D88-9368-04F814782BCB wds:Q37456446-CA8651FC-8DAE-459E-9386-BCBC4FCEAFFC wds:Q37456446-CC80D733-C228-47B4-A998-691DA39099CD wds:Q37456446-CD94C541-D359-4677-986D-D9838358E750 wds:Q37456446-E0D75F23-32E8-46FF-A4E6-4F0DDE847CD1 wds:Q37456446-E6B69ED6-A6AE-4ED7-883D-D571675D19BA wds:Q37456446-E7D427F2-C354-4A6E-AE47-FBC5D183F37C wds:Q37456446-E9BFE8AF-CE65-4712-9E16-0EA238006550 wds:Q37456446-EE85235A-53B3-43D6-B597-8CEF17FDCE13 wds:Q37456446-F348F15A-9DA1-4518-8178-4919C38A57EA wds:Q37456446-F9FC646E-7C76-4D02-8C18-D563DF88EEC5
cites work	Validation of Egg Yolk Antibody Testing as a Method to Determine Influenza Status in White Leghorn Hens Correlation of pathogenicity and gene constellation of influenza A viruses II. Highly neurovirulent recombinants derived from non-neurovirulent or weakly neurovirulent parent virus strains Molecular determinants within the surface proteins involved in the pathogenicity of H5N1 influenza viruses in chickens Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease Live, attenuated influenza A H5N1 candidate vaccines provide broad cross-protection in mice and ferrets Characterization of an avian influenza A (H5N1) virus isolated from a child with a fatal respiratory illness Strategies for mitigating an influenza pandemic Vaccines for pandemic influenza Clinical features and rapid viral diagnosis of human disease associated with avian influenza A H5N1 virus. Multiple amino acid residues confer temperature sensitivity to human influenza virus vaccine strains (FluMist) derived from cold-adapted A/Ann Arbor/6/60. Enhancement of the infectivity of influenza A and B viruses by proteolytic cleavage of the hemagglutinin polypeptide Safety, immunogenicity and efficacy of intranasal, live attenuated influenza vaccine Proteolytic cleavage of influenza virus hemagglutinins: primary structure of the connecting peptide between HA1 and HA2 determines proteolytic cleavability and pathogenicity of Avian influenza viruses Generation and characterization of a cold-adapted influenza A H9N2 reassortant as a live pandemic influenza virus vaccine candidate. Development and persistence of local and systemic antibody responses in adults given live attenuated or inactivated influenza A virus vaccine. A single amino acid in the PB2 gene of influenza A virus is a determinant of host range. Imparting temperature sensitivity and attenuation in ferrets to A/Puerto Rico/8/34 influenza virus by transferring the genetic signature for temperature sensitivity from cold-adapted A/Ann Arbor/6/60. A new generation of modified live-attenuated avian influenza viruses using a two-strategy combination as potential vaccine candidates Influenza virus A pathogenicity: the pivotal role of hemagglutinin Comparative efficacy of neutralizing antibodies elicited by recombinant hemagglutinin proteins from avian H5N1 influenza virus Establishment of multiple sublineages of H5N1 influenza virus in Asia: Implications for pandemic control Molecular basis for high virulence of Hong Kong H5N1 influenza A viruses Polygenic virulence factors involved in pathogenesis of 1997 Hong Kong H5N1 influenza viruses in mice Sequence requirements for cleavage activation of influenza virus hemagglutinin expressed in mammalian cells The structure of the hemagglutinin, a determinant for the pathogenicity of influenza viruses Increased anti-influenza A virus cytotoxic T cell activity following vaccination of the chronically ill elderly with live attenuated or inactivated influenza virus vaccine Acquisition of a polybasic hemagglutinin cleavage site by a low-pathogenic avian influenza virus is not sufficient for immediate transformation into a highly pathogenic strain Development and characterization of cold-adapted viruses for use as live virus vaccines The polymerase complex genes contribute to the high virulence of the human H5N1 influenza virus isolate A/Vietnam/1203/04. Engineered viral vaccine constructs with dual specificity: avian influenza and Newcastle disease Recombinant Paramyxovirus Type 1-Avian Influenza-H7 Virus as a Vaccine for Protection of Chickens Against Influenza and Newcastle Disease Correlation of Pathogenicity and Gene Constellation of Influenza A Viruses. III. Non-pathogenic Recombinants Derived from Highly Pathogenic Parent Strains Gene constellation of live influenza A vaccines
author name string	wds:Q37456446-0FC3244F-4E48-4046-A3E0-833682576C19 wds:Q37456446-26977DCC-C016-4A47-8B97-6F6F8ACCEC12 wds:Q37456446-64169F91-EEE8-4AB8-8CF1-5A09BA736BA2 wds:Q37456446-69014450-8B94-42FD-A757-21304EE2E094
author name string	Li-Mei Chen Yumiko Matsuoka Purvi D Desai Michael P Marino
rdfs:label	The influence of the multi-basic cleavage site of the H5 hemagglutinin on the attenuation, immunogenicity and efficacy of a live attenuated influenza A H5N1 cold-adapted vaccine virus (en) The influence of the multi-basic cleavage site of the H5 hemagglutinin on the attenuation, immunogenicity and efficacy of a live attenuated influenza A H5N1 cold-adapted vaccine virus (ast) The influence of the multi-basic cleavage site of the H5 hemagglutinin on the attenuation, immunogenicity and efficacy of a live attenuated influenza A H5N1 cold-adapted vaccine virus. (nl)
skos:prefLabel	The influence of the multi-basic cleavage site of the H5 hemagglutinin on the attenuation, immunogenicity and efficacy of a live attenuated influenza A H5N1 cold-adapted vaccine virus (en) The influence of the multi-basic cleavage site of the H5 hemagglutinin on the attenuation, immunogenicity and efficacy of a live attenuated influenza A H5N1 cold-adapted vaccine virus (ast)

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