About: The adjuvant MF59 induces ATP release from muscle that potentiates response to vaccination

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About: The adjuvant MF59 induces ATP release from muscle that potentiates response to vaccination Goto Sponge NotDistinct Permalink

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scientific article published on 09 December 2013

Attributes	Values
rdf:type	Item
description	videnskabelig artikel (da) article científic (ca) articolo scientifico (it) artigo científico (pt) bilimsel makale (tr) vedecký článok (sk) vetenskaplig artikel (sv) vědecký článek (cs) wetenschappelijk artikel (nl) wissenschaftlicher Artikel (de) научни чланак (sr) article scientifique (fr) artículu científicu espublizáu en 2013 (ast) наукова стаття, опублікована в грудні 2013 (uk) 2013年學術文章 (zh) scientific article published on 09 December 2013 (en) مقالة علمية نشرت في 09 ديسمبر 2013 (ar)
publication date	wds:Q37421379-D2DE0650-0FB4-47B1-83AB-E9656B4D41ED
publication date	2013-12-09 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q37421379-ED2E8E44-852B-469B-86C0-E68C83F88BCF
language of work or name	English
cites work	wds:Q37421379-0174659D-6019-48CD-853B-4191403F92F2 wds:Q37421379-175AAD60-6C75-475D-B45C-391942FD6417 wds:Q37421379-196E9482-ACDA-4B24-AF38-E82F8DEA63A6 wds:Q37421379-1AF6A867-F09C-4CBB-99C3-195311F16663 wds:Q37421379-21B105D5-F82C-48D2-A5A5-C69C263B8C17 wds:Q37421379-2C653A8B-33BD-47CB-9464-D22B6ACB6BD7 wds:Q37421379-2D8C3DEF-3824-4D7E-AE6D-B2507BCCD3F8 wds:Q37421379-391BAE65-2078-4F84-95E9-D872DB1DA285 wds:Q37421379-55E1CFE9-DA73-435D-A2B8-66F289C8CA97 wds:Q37421379-59153257-A2A9-42FE-9C0B-94A3527AED14 wds:Q37421379-669FFCD1-6115-4583-A4F4-1FBF0206138E wds:Q37421379-78E905D8-73D1-490D-832F-08E4B7CCEC33 wds:Q37421379-83C8CE30-1891-465C-BC58-03237B4875F4 wds:Q37421379-8ACB2D08-2E7F-435B-8C0B-A723931AD037 wds:Q37421379-91CA650E-5664-4087-82AF-A45FD7866690 wds:Q37421379-97DF6F19-3CBD-40BB-87A8-63B23FC8CE9A wds:Q37421379-98FB6C10-781D-44FA-AB22-7E745FFE3092 wds:Q37421379-9D9F7BD0-EFAC-4681-9678-3164BB096164 wds:Q37421379-A6EE236F-2D46-4920-B60A-F928D4A0C54D wds:Q37421379-B0B978D1-3406-4652-B449-F6D7B65D7992 wds:Q37421379-B5B9F0C8-DA48-4B50-A669-E8FC21B42D83 wds:Q37421379-B73ECBF5-02A2-4164-9947-40584EB9DD2A wds:Q37421379-B85CB572-9973-48C4-954A-D2FCDBD95BBC wds:Q37421379-BC274A34-0899-4B3F-90CD-72C954FA7524 wds:Q37421379-BF4D4E86-ED0A-4980-A7FB-4EFF2E7E38C6 wds:Q37421379-C6773BEF-3508-48FA-B18E-DD5376E015CC wds:Q37421379-D020AB86-B5B1-4A20-BEBA-E269D20BDFF3 wds:Q37421379-D3D21A10-AD84-4B21-885D-498A7614D2D2 wds:Q37421379-E6BE71BB-C22A-41F9-A94C-C99EF39F4353 wds:Q37421379-F0F07191-A14F-4BCD-97FC-78E2C76E6E92 wds:Q37421379-F1356E39-50DB-4A8C-8ABD-3A5B2249E61C wds:Q37421379-F13597D5-FCB2-4A00-A490-8A0C78D81F92 wds:Q37421379-F41FC480-C6A9-4BD4-80BA-034DF407B87F wds:Q37421379-F5391F1B-BF54-4DDF-A652-BF0E5745E9B1
cites work	Immune cell regulation by autocrine purinergic signalling A 2020 vision for vaccines against HIV, tuberculosis and malaria. Calcium imaging of muscle cells treated with snake myotoxins reveals toxin synergism and presence of acceptors. Cutting edge: inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3. The adjuvants aluminum hydroxide and MF59 induce monocyte and granulocyte chemoattractants and enhance monocyte differentiation toward dendritic cells Vaccine adjuvants alum and MF59 induce rapid recruitment of neutrophils and monocytes that participate in antigen transport to draining lymph nodes Mechanism of action of licensed vaccine adjuvants Increased level of extracellular ATP at tumor sites: in vivo imaging with plasma membrane luciferase Inflammasome-independent role of the apoptosis-associated speck-like protein containing CARD (ASC) in the adjuvant effect of MF59. Physiology and pathophysiology of purinergic neurotransmission P2 receptors and immunity. How tissue injury alarms the immune system and causes a systemic inflammatory response syndrome Molecular and cellular signatures of human vaccine adjuvants. The danger signal, extracellular ATP, is a sensor for an airborne allergen and triggers IL-33 release and innate Th2-type responses Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells DNA released from dying host cells mediates aluminum adjuvant activity MF59 and Pam3CSK4 Boost Adaptive Responses to Influenza Subunit Vaccine through an IFN Type I-Independent Mechanism of Action Combination adjuvants for the induction of potent, long-lasting antibody and T-cell responses to influenza vaccine in mice. Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants Macrophages and dendritic cells in normal and regenerating murine skeletal muscle The therapeutic potential of modifying inflammasomes and NOD-like receptors Host DNA released in response to aluminum adjuvant enhances MHC class II-mediated antigen presentation and prolongs CD4 T-cell interactions with dendritic cells Adjuvanticity of the oil-in-water emulsion MF59 is independent of Nlrp3 inflammasome but requires the adaptor protein MyD88 Enhancement of humoral response against human influenza vaccine with the simple submicron oil/water emulsion adjuvant MF59. Vaccine adjuvants: putting innate immunity to work How do adjuvants work? Important considerations for new generation adjuvants Immune mechanisms of protection: can adjuvants rise to the challenge? P2 receptors and extracellular ATP: a novel homeostatic pathway in inflammation Mechanism of action of clinically approved adjuvants Bothrops snake myotoxins induce a large efflux of ATP and potassium with spreading of cell damage and pain Apyrases (ATP diphosphohydrolases, EC 3.6.1.5): function and relationship to ATPases Purinergic stimulation of human mesenchymal stem cells potentiates their chemotactic response to CXCL12 and increases the homing capacity and production of proinflammatory cytokines Purinergic mechanism in the immune system: A signal of danger for dendritic cells. Immunolocalization of the sarcolemmal Ca2+/Mg2+ ecto-ATPase (myoglein) in rat myocardium.
author name string	wds:Q37421379-12E1FF4C-46C3-42C5-8734-302D1D6741E7 wds:Q37421379-4584BC33-A819-4624-BC65-D566DBEACA8D wds:Q37421379-6B480BD4-4260-4EFF-9FDA-0F9EBC14167E wds:Q37421379-6E34BAFB-5BBC-4BB5-A35C-F19DF68FE89B wds:Q37421379-75F70688-4D9B-46A0-8A1D-84372AC33557 wds:Q37421379-9048C4E2-CE04-4081-B452-5F8D2B80836C wds:Q37421379-9F3BB430-148D-4A5E-915D-4717723329D6 wds:Q37421379-BDFB6C0B-DA59-473E-987F-40F2C5E3B72D wds:Q37421379-BF822785-BE2F-4BE8-889C-7400CFB8E35E
author name string	Ennio De Gregorio

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