About: Entry of substances into perilymph through the bone of the otic capsule after intratympanic applications in guinea pigs: implications for local drug delivery in humans.

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About: Entry of substances into perilymph through the bone of the otic capsule after intratympanic applications in guinea pigs: implications for local drug delivery in humans. Goto Sponge NotDistinct Permalink

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scientific article published on February 2009

Attributes	Values
rdf:type	Item
description	videnskabelig artikel (da) article científic (ca) articolo scientifico (it) artigo científico (pt) bilimsel makale (tr) vedecký článok (sk) vetenskaplig artikel (sv) vědecký článek (cs) wetenschappelijk artikel (nl) wissenschaftlicher Artikel (de) научни чланак (sr) article scientifique (fr) artículu científicu espublizáu en 2009 (ast) наукова стаття, опублікована в лютому 2009 (uk) مقالة علمية نشرت في فبراير 2009 (ar) scientific article published on February 2009 (en)
publication date	wds:Q37311062-9C360D28-1782-493A-B088-C4F507E18CCC
publication date	2009-02-01 00:00:00Z (xsd:dateTime)
cites work	wds:Q37311062-000315D9-DEA8-4E28-B87D-3D5A31062A46 wds:Q37311062-178A857F-34F8-4ED9-86F2-4627F14A3394 wds:Q37311062-18A80519-6F43-44D6-B0AD-FA3D1B94A751 wds:Q37311062-1BEE10EC-82FE-4230-BD00-AD0E63DD2D9F wds:Q37311062-4BE8ED15-1307-42A0-A459-1476CA883687 wds:Q37311062-519B12AA-875C-48C7-ACBA-1BA850C4C80A wds:Q37311062-5CAF63E6-E0D3-4B12-A926-CB03CF6A61E0 wds:Q37311062-6679C565-8426-4909-AA50-2E9BD5F110A2 wds:Q37311062-75529420-A403-4585-8B36-578E0A006587 wds:Q37311062-85BA9435-372E-4F6A-ADE0-A04C2B6DB200 wds:Q37311062-9A6B9A1D-6C28-4B50-BDD0-E1EE2EEEAD03 wds:Q37311062-A6D2DF2E-3E13-4EEA-A93E-9E0EE9F1E449 wds:Q37311062-AD17062E-D152-4A71-8E32-B00A7AD0CEA2 wds:Q37311062-ADCCDAA8-444D-4A31-9F48-40948B57FC9D wds:Q37311062-BE7F3AC1-874C-4773-86F0-05AA69A2C969 wds:Q37311062-F6CB5BB6-B14F-43C3-B161-CD25460F5E21 wds:Q37311062-FD171BAA-0E83-41B8-A937-BDDEA8355DE8 wds:Q37311062-FE298059-5F23-4EB3-9FF2-912FBC3BB30F
cites work	The history of intratympanic drug therapy in otology Osteoprotegrin knockout mice demonstrate abnormal remodeling of the otic capsule and progressive hearing loss Permeability of the round window membrane is influenced by the composition of applied drug solutions and by common surgical procedures Intratympanic injection of dexamethasone: time course of inner ear distribution and conversion to its active form. Quantification of solute entry into cochlear perilymph through the round window membrane Delivery of neurotrophin-3 to the cochlea using alginate beads. Bone lining cells of the mammalian cochlea Temporal bone density measurements using CT in otosclerosis. Demonstration of a longitudinal concentration gradient along scala tympani by sequential sampling of perilymph from the cochlear apex. Concentration gradient along the scala tympani after local application of gentamicin to the round window membrane Contamination of perilymph sampled from the basal cochlear turn with cerebrospinal fluid. Cochlear hair cell loss in single-dose versus continuous round window administration of gentamicin AM-111 reduces hearing loss in a guinea pig model of acute labyrinthitis. Dexamethasone concentration gradients along scala tympani after application to the round window membrane Gentamicin uptake in the chinchilla inner ear. Dependence of hearing changes on the dose of intratympanically applied gentamicin: a meta-analysis using mathematical simulations of clinical drug delivery protocols. Intravital microlesions in the human otic capsule. Detection, classification and pathogenetic significance revisited Apical cochlear nerve exposed to perilymph in the gerbil and rat.
author name string	wds:Q37311062-4A0BBE8A-A734-4FED-BA2B-C6094FF95399 wds:Q37311062-C5097B9B-AFFF-4792-B70B-AD0AF12C3F99
author name string	Anthony A Mikulec Jared J Hartsock
rdfs:label	Entry of substances into perilymph through the bone of the otic capsule after intratympanic applications in guinea pigs: implications for local drug delivery in humans. (en) Entry of substances into perilymph through the bone of the otic capsule after intratympanic applications in guinea pigs: implications for local drug delivery in humans. (nl) Entry of substances into perilymph through the bone of the otic capsule after intratympanic applications in guinea pigs: implications for local drug delivery in humans. (ast)
skos:prefLabel	Entry of substances into perilymph through the bone of the otic capsule after intratympanic applications in guinea pigs: implications for local drug delivery in humans. (en) Entry of substances into perilymph through the bone of the otic capsule after intratympanic applications in guinea pigs: implications for local drug delivery in humans. (nl) Entry of substances into perilymph through the bone of the otic capsule after intratympanic applications in guinea pigs: implications for local drug delivery in humans. (ast)
name	Entry of substances into perilymph through the bone of the otic capsule after intratympanic applications in guinea pigs: implications for local drug delivery in humans. (en) Entry of substances into perilymph through the bone of the otic capsule after intratympanic applications in guinea pigs: implications for local drug delivery in humans. (nl) Entry of substances into perilymph through the bone of the otic capsule after intratympanic applications in guinea pigs: implications for local drug delivery in humans. (ast)
author	wds:Q37311062-82B0038A-41F3-4D78-AA80-518085435975 wds:Q37311062-B6B43DD9-66A4-4A2D-99E0-93D19A538EA5
author	Stefan Plontke Alec N. Salt
title	wds:Q37311062-E2BDB271-6DC0-4F36-94CB-1CD2C884C73F
title	Entry of substances into perilymph through the bone of the otic capsule after intratympanic applications in guinea pigs: implications for local drug delivery in humans (en)
page(s)	wds:Q37311062-D45A7B29-3D83-4C66-8991-397CC072AFFA
page(s)	131-138
instance of	wds:Q37311062-5BCB5112-F3E7-4B43-80CA-5522A79C9A7E
instance of	scholarly article
main subject	wds:Q37311062-9106A0C6-221E-40F0-BC25-516BFD2F1875
main subject	drug delivery
PubMed ID	wds:Q37311062-2B3037A2-AC62-4D59-A093-EA5BE7CEC815
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/19180674
PubMed ID	19180674
published in	wds:Q37311062-1CDEBF39-0A0F-4219-923D-B9F8A7C17DBA
published in	Otology & Neurotology
issue	wds:Q37311062-90BC2D18-3A64-474B-83AA-9532DE2FA848
volume	wds:Q37311062-9EB15159-5F70-4AE7-AA5F-9345C2BC07D4
issue	2
volume	30
DOI	wds:Q37311062-F1DC5E6C-D329-4BBB-AAE9-9B682C85BE26
DOI	http://dx.doi.org/10.1097/MAO.0B013E318191BFF8
DOI	10.1097/MAO.0B013E318191BFF8
ResearchGate publication ID	wds:Q37311062-78CBD76D-3124-4CEA-9E49-272B8DAC7E9D
ResearchGate publication ID	23960719
PMCID	wds:Q37311062-3077DE76-5F81-4BB2-99C3-CAB30B079705
PMCID	2729139
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q37311062
is cites work of	Intra-tympanic delivery of short interfering RNA into the adult mouse cochlea Principles of local drug delivery to the inner ear. Marker entry into vestibular perilymph via the stapes following applications to the round window niche of guinea pigs

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