About: Structural and functional basis for therapeutic modulation of p53 signaling.

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About: Structural and functional basis for therapeutic modulation of p53 signaling. Goto Sponge NotDistinct Permalink

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scientific article published on October 2008

Attributes	Values
rdf:type	Item
description	videnskabelig artikel (da) article científic (ca) articolo scientifico (it) artigo científico (pt) bilimsel makale (tr) vedecký článok (sk) vetenskaplig artikel (sv) vědecký článek (cs) wetenschappelijk artikel (nl) wissenschaftlicher Artikel (de) научни чланак (sr) article scientifique (fr) artículu científicu espublizáu en 2008 (ast) наукова стаття, опублікована в жовтні 2008 (uk) مقالة علمية نشرت في أكتوبر 2008 (ar) scientific article published on October 2008 (en)
publication date	wds:Q37300876-3363D159-FFAC-4627-AA02-F73DDF1B12D0
publication date	2008-10-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q37300876-F107750A-D54B-4F16-A706-BAB63B56EB91
language of work or name	English
cites work	wds:Q37300876-2FD27A4F-16FC-4717-8033-AB5AC2112949
cites work	Transactivation of the EGR1 gene contributes to mutant p53 gain of function
author name string	wds:Q37300876-A58A998B-D279-4F4C-9DF3-70E7D51B9CCD wds:Q37300876-B066F926-CE7B-4AC9-AD9B-F8166EA14F6D wds:Q37300876-D7AADD36-E8F7-42EE-88BA-F7C5F1502990
author name string	Emily A Bassett Wenge Wang Farzan Rastinejad
rdfs:label	Structural and functional basis for therapeutic modulation of p53 signaling. (en) Structural and functional basis for therapeutic modulation of p53 signaling. (nl) Structural and functional basis for therapeutic modulation of p53 signaling. (ast)
skos:prefLabel	Structural and functional basis for therapeutic modulation of p53 signaling. (en) Structural and functional basis for therapeutic modulation of p53 signaling. (nl) Structural and functional basis for therapeutic modulation of p53 signaling. (ast)
name	Structural and functional basis for therapeutic modulation of p53 signaling. (en) Structural and functional basis for therapeutic modulation of p53 signaling. (nl) Structural and functional basis for therapeutic modulation of p53 signaling. (ast)
author	wds:Q37300876-DAD6BA1F-2A20-419E-8A34-5FF1BC0679D4
author	Wafik El-Deiry
title	wds:Q37300876-3C38B644-5556-49AA-A6E9-D33245DE1E0C
title	Structural and functional basis for therapeutic modulation of p53 signaling (en)
page(s)	wds:Q37300876-CC84AD35-898C-41DA-A022-4BF7BB9B4902
page(s)	6376-6386
instance of	wds:Q37300876-122D934B-50AA-4777-A651-1CD90146E076 wds:Q37300876-d5885103-7fed-4441-bcb7-6402324b5c93
instance of	review article scholarly article
PubMed ID	wds:Q37300876-3DF6C78B-7402-4595-B972-06484D9612D0
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/18927276
PubMed ID	18927276
published in	wds:Q37300876-CD08E71F-5514-4790-848C-D1B56A891342
published in	Clinical Cancer Research
issue	wds:Q37300876-C7E3C44A-0D86-46EB-97E6-9A0629757C01
volume	wds:Q37300876-6AAB568E-8610-4914-AF75-FFC7744FD1DA
issue	20
volume	14
DOI	wds:Q37300876-0A66971B-B761-4184-A4A5-DD7091A98B12
DOI	http://dx.doi.org/10.1158/1078-0432.CCR-08-1526
DOI	10.1158/1078-0432.CCR-08-1526
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q37300876
is cites work of	Targeting p53 for Novel Anticancer Therapy Radiation-induced cell death mechanisms Cardiac glycosides inhibit p53 synthesis by a mechanism relieved by Src or MAPK inhibition APR-246 potently inhibits tumour growth and overcomes chemoresistance in preclinical models of oesophageal adenocarcinoma Attractor landscape analysis reveals feedback loops in the p53 network that control the cellular response to DNA damage Mechanisms of Cisplatin nephrotoxicity Cisplatin-induced Kidney Dysfunction and Perspectives on Improving Treatment Strategies Clinical utility of recombinant adenoviral human p53 gene therapy: current perspectives Rb deletion in mouse mammary progenitors induces luminal-B or basal-like/EMT tumor subtypes depending on p53 status The combination of 5-fluorouracil plus p53 pathway restoration is associated with depletion of p53-deficient or mutant p53-expressing putative colon cancer stem cells Signalling mechanisms involved in renal pathological changes during cisplatin-induced nephropathy Identification of flubendazole as potential anti-neuroblastoma compound in a large cell line screen Targeting wild-type and mutant p53 with small molecule CP-31398 blocks the growth of rhabdomyosarcoma by inducing reactive oxygen species-dependent apoptosis. Targeting cancer stem cells with p53 modulators. Asialoglycoprotein receptor-magnetic dual targeting nanoparticles for delivery of RASSF1A to hepatocellular carcinoma Mutants of the tumour suppressor p53 L1 loop as second-site suppressors for restoring DNA binding to oncogenic p53 mutations: structural and biochemical insights Targeting apoptosis in cancer therapy Targeting Insulin-Like Growth Factor Binding Protein-3 Signaling in Triple-Negative Breast Cancer A p53-stabilizing agent, CP-31398, induces p21 expression with increased G2/M phase through the YY1 transcription factor in esophageal carcinoma defective of the p53 pathway A combination of p53-activating APR-246 and phosphatidylserine-targeting antibody potently inhibits tumor development in hormone-dependent mutant p53-expressing breast cancer xenografts. APR-246 alone and in combination with a phosphatidylserine-targeting antibody inhibits lung metastasis of human triple-negative breast cancer cells in nude mice
is cites work of	wds:Q33655329-2DDDC57F-602C-4FE3-BAF9-86D2CF5573A1 wds:Q34415371-FED5CEAB-CB61-4E3A-9AC9-D3BCDF81F821 wds:Q38127618-A6859109-1533-4B3E-9289-CBCE4C20BC1E wds:Q33516218-DD58C890-E11C-4238-884C-C1E7E437A7E8 wds:Q28080842-BC976D49-6487-4406-8519-03003A6757D9 wds:Q30496322-A35D51DB-E3B8-4E97-8F8A-3A78F887CF39 wds:Q26996320-DB31E5C5-D773-42E4-97D7-EB9845DDDB64 wds:Q34069279-77915ADC-EFBC-48A9-9FF4-BD7D7AA307F6 wds:Q26801886-584529B4-E154-479E-A741-D87E6AFDE2E5 wds:Q34116777-41AD1E07-C33F-49FD-9EB9-8BA22BE021BB wds:Q38913917-DD96742E-B6E4-4158-88D9-24AB0F2887BE wds:Q36621264-76852BAB-612E-4031-B8EF-E1E4B6ADFF59 wds:Q37564349-F11CDEA7-7C63-4FF6-A8DC-AA3DBC760203 wds:Q90168991-F962A859-01E2-4EB2-BC44-B480411DE7C2 wds:Q38851714-8ADFF21C-1E79-4828-A83F-51DEFB71C8AB wds:Q39812929-2A91C116-F471-42D9-941B-24CFA1CF5ACA wds:Q52722381-A48AA799-DEBF-42B4-BFB2-C0E713DAB521 wds:Q61808050-CE18196E-C0AA-43F7-A3F6-9A3FF1B74B42

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