About: Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells

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About: Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells Goto Sponge NotDistinct Permalink

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scientific article published on 20 May 2009

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rdf:type	Item
description	videnskabelig artikel (da) article científic (ca) articolo scientifico (it) artigo científico (pt) bilimsel makale (tr) vedecký článok (sk) vetenskaplig artikel (sv) vědecký článek (cs) wetenschappelijk artikel (nl) wissenschaftlicher Artikel (de) научни чланак (sr) article scientifique (fr) artículu científicu espublizáu en 2009 (ast) наукова стаття, опублікована в травні 2009 (uk) scientific article published on 20 May 2009 (en) مقالة علمية نشرت في 20 مايو 2009 (ar)
publication date	wds:Q37256675-8317CD8C-F0EE-46D0-94C5-89C111EFC6B6
publication date	2009-05-20 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q37256675-F080B572-956C-4335-B8CF-1C33CAA82475
language of work or name	English
cites work	wds:Q37256675-0247356F-ADD0-4427-B79C-AE7C93B99138 wds:Q37256675-06C69BCD-11A3-4BFF-93D2-396CE03083A3 wds:Q37256675-0C00A022-6416-43F2-94FF-6077D1E3D530 wds:Q37256675-1181ACBC-269B-4965-880A-34430F2DE37B wds:Q37256675-1B1DCD25-7722-473E-975E-1A5B6B82F212 wds:Q37256675-2405BBC3-DAB8-4BC4-AFA2-CDCD39AF2972 wds:Q37256675-2D1ADF9C-D0F7-4389-A385-F575034B631D wds:Q37256675-2F18CE12-F735-4C93-809E-FF37C7CE37E6 wds:Q37256675-31B1792C-0D19-466F-8390-F7D8AFAC286D wds:Q37256675-394E497B-3A5C-42BF-80D6-1E05DCFECECA wds:Q37256675-39679EA1-07FE-434F-850A-C46D2CC886CF wds:Q37256675-5454DDF8-2BD3-4335-A5DD-E708AB2789A3 wds:Q37256675-5621FD75-B63A-4318-A787-586AFCAC1524 wds:Q37256675-5A5D9E40-C7A2-4317-B1CF-1341AD5EC4C5 wds:Q37256675-5EAFA20F-B16B-4C34-B32D-CEE8302F871E wds:Q37256675-5F34070B-3064-4D6E-892B-DECCBAF81DF7 wds:Q37256675-5F74C573-6D5E-4613-B7B6-57465B907E08 wds:Q37256675-6AA81BBF-A218-4633-9C72-DDA8883E6F3A wds:Q37256675-6B21221C-CA4F-4C48-AE54-2EDD606E76E0 wds:Q37256675-82A00302-7FF9-4AD7-972E-864DC68A3EBC wds:Q37256675-88D72CBF-54B9-4D53-8DF3-61AB11A48D59 wds:Q37256675-8F287142-8BED-4937-816F-D597815EC6C0 wds:Q37256675-939E8642-9729-40C0-A4C8-7C6FDB8F2FEA wds:Q37256675-94D6814A-DBE3-4EC5-9A3C-903A08139EB6 wds:Q37256675-A3571647-73EF-4EAA-B59C-3ADAC6DEDA20 wds:Q37256675-B0BE90CA-D6A3-4999-B4F8-3330B186133A wds:Q37256675-BFFC1560-E6B0-498D-A473-119E9DAAF46E wds:Q37256675-C90BFD84-6C6D-44CC-BCA5-6C2A014E032F wds:Q37256675-CE6D50F8-F937-45A5-BD47-ED44B2712536 wds:Q37256675-D28E2704-A048-4BA2-BF01-615609CD6997 wds:Q37256675-D9BCE050-DDC5-479C-961D-7C2EDDF4BDDF wds:Q37256675-F65856C2-F80C-456E-BC10-7673055BC56B
cites work	Antigen load and viral sequence diversification determine the functional profile of HIV-1-specific CD8+ T cells A whole-genome association study of major determinants for host control of HIV-1 Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection Analysis of total human immunodeficiency virus (HIV)-specific CD4(+) and CD8(+) T-cell responses: relationship to viral load in untreated HIV infection A Novel Approach to Antigen-Specific Deletion of CTL with Minimal Cellular Activation Using α3 Domain Mutants of MHC Class I/Peptide Complex Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract Prognosis in HIV-1 infection predicted by the quantity of virus in plasma Consistent cytotoxic-T-lymphocyte targeting of immunodominant regions in human immunodeficiency virus across multiple ethnicities Abundant expression of granzyme A, but not perforin, in granules of CD8+ T cells in GALT: implications for immune control of HIV-1 infection CD8+ lymphocytes can control HIV infection in vitro by suppressing virus replication Characterization of human immunodeficiency virus type 1-specific cytotoxic T lymphocyte clones isolated during acute seroconversion: recognition of autologous virus sequences within a conserved immunodominant epitope Toward an understanding of the correlates of protective immunity to HIV infection Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome Programmed cell death in peripheral lymphocytes from HIV-infected persons: increased susceptibility to apoptosis of CD4 and CD8 T cells correlates with lymphocyte activation and with disease progression. Marked epitope- and allele-specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection Recognition of a defined region within p24 gag by CD8+ T cells during primary human immunodeficiency virus type 1 infection in individuals expressing protective HLA class I alleles The failed HIV Merck vaccine study: a step back or a launching point for future vaccine development? Consistent effects of TSG101 genetic variability on multiple outcomes of exposure to human immunodeficiency virus type 1 CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract Natural history of human immunodeficiency virus type 1 viremia after seroconversion and proximal to AIDS in a large cohort of homosexual men. Multicenter AIDS Cohort Study Suppression of human immunodeficiency virus type 1 replication by CD8+ cells: evidence for HLA class I-restricted triggering of cytolytic and noncytolytic mechanisms Gag-specific CD8+ T lymphocytes recognize infected cells before AIDS-virus integration and viral protein expression Evolution of CD8+ T cell immunity and viral escape following acute HIV-1 infection Prognostic value of HIV-1 RNA, CD4 cell count, and CD4 Cell count slope for progression to AIDS and death in untreated HIV-1 infection HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8(+) T Cell Response against HIV-1. Substantial differences in specificity of HIV-specific cytotoxic T cells in acute and chronic HIV infection Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load. Comprehensive analysis of human immunodeficiency virus type 1 (HIV-1)-specific gamma interferon-secreting CD8+ T cells in primary HIV-1 infection Selective depletion of high-avidity human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T cells after early HIV-1 infection Loss of Viral Control in Early HIV‐1 Infection Is Temporally Associated with Sequential Escape from CD8+T Cell Responses and Decrease in HIV–1–Specific CD4+and CD8+T Cell Frequencies Primary HIV type 1 infection
author name string	wds:Q37256675-22B44075-8B42-4011-A805-9900C9903372 wds:Q37256675-F2FF2692-22E0-476A-830A-69B1A3845D02
author name string	Ying Qi Heiko K Jessen
rdfs:label	Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells (en) Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells (nl) Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells (ast)
skos:prefLabel	Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells (en) Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells (nl) Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells (ast)
name	Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells (en) Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells (nl) Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells (ast)
author	wds:Q37256675-0B80E34F-BCAB-4F08-863F-A3776FCBD0CD wds:Q37256675-1318AFB7-F74F-478C-BC6E-0B8A5165504E

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