About: Histone modifications depict an aberrantly heterochromatinized FMR1 gene in fragile x syndrome

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About: Histone modifications depict an aberrantly heterochromatinized FMR1 gene in fragile x syndrome Goto Sponge NotDistinct Permalink

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scientific article published on 13 September 2002

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rdf:type	Item
description	videnskabelig artikel (da) article científic (ca) articolo scientifico (it) artigo científico (pt) bilimsel makale (tr) vedecký článok (sk) vetenskaplig artikel (sv) vědecký článek (cs) wetenschappelijk artikel (nl) wissenschaftlicher Artikel (de) научни чланак (sr) article scientifique (fr) artículu científicu espublizáu en 2002 (ast) наукова стаття, опублікована у вересні 2002 (uk) scientific article published on 13 September 2002 (en) مقالة علمية نشرت في 13 سبتمبر 2002 (ar)
publication date	wds:Q37203166-1195F2FE-B66A-48EC-BB47-DC6104DB74FB
publication date	2002-09-13 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q37203166-A16C0460-937E-4E8A-87AA-2FF1257A5608
language of work or name	English
cites work	wds:Q37203166-02EF7911-A6A6-4F32-B696-65AC2EBFB810 wds:Q37203166-0C574A14-E073-423A-AE72-1FCE26CC7584 wds:Q37203166-0CBFDBCE-7810-437F-A033-72E37FCDAAE0 wds:Q37203166-1B0AC7C0-EE10-4096-915F-700BDD54F2D4 wds:Q37203166-21949354-6C31-4B5B-A5ED-0F9B582E0174 wds:Q37203166-23C8EEED-DC09-40B9-B620-5ED2BD7BFEF0 wds:Q37203166-2E49938A-8C00-4350-AD32-ADF4F47E8846 wds:Q37203166-306ACBB1-5A6E-4E28-92A6-2845FD6B6A02 wds:Q37203166-30EB4493-2DB9-4381-B0F0-E69DC250CE78 wds:Q37203166-422B9EF9-150A-4265-9A86-5F77C18AED21 wds:Q37203166-458A4FD8-2F32-4CBC-954E-C28B01EA4610 wds:Q37203166-51D15B0A-6D47-4EF2-A4CB-F3A6D7543E43 wds:Q37203166-5689D81B-FDEA-433B-A48B-542093F3EBBC wds:Q37203166-5BD78997-348E-4236-B6FA-8C4D19D7752D wds:Q37203166-5CAFFFBA-5B12-4BA5-BBC7-91FF33053957 wds:Q37203166-6572763D-41BD-465F-8787-029A8F0E3AE2 wds:Q37203166-770136F0-C5C6-44BE-89BF-3028EC766DEF wds:Q37203166-79689560-AED6-4EBA-B2B2-ECAF9BF310D0 wds:Q37203166-85FAFA9A-4722-40E5-A1E1-BFD94C192E2E wds:Q37203166-87992A02-4AC7-46EC-8FDF-B524F40E5C65 wds:Q37203166-8B85E10E-AB19-484E-86E6-D9CEF8C9A967 wds:Q37203166-996C6EA5-ADB7-4D7A-B2A0-CBC58EC5F22E wds:Q37203166-9C8E9929-957E-4A83-8F6B-E215FF9C1F35 wds:Q37203166-9FA741A3-8E96-4E27-964C-7A5F4A62F1B2 wds:Q37203166-A0609E19-B436-434C-B736-A471487916A5 wds:Q37203166-A0A9FCE9-1C72-4BD2-9D57-F93B07F39050 wds:Q37203166-A9FE45D5-3930-402D-A16D-EA00ED1AC014 wds:Q37203166-C97A82D1-C809-48E2-8134-8B63157A0D1D wds:Q37203166-CFCF39AB-AC55-4C21-AA4C-C541D1869018 wds:Q37203166-D8762727-CB0A-4662-B6F0-ECEE8FCD1DF6 wds:Q37203166-DC194174-45A7-45B3-B83D-073BBB43A415 wds:Q37203166-E6CA62BA-A698-4E84-B55D-88D528186F4B wds:Q37203166-EB2F39F8-0EAF-496A-83FD-E56574A3BC19 wds:Q37203166-F0413F33-BAA9-4DCD-BBF6-F84CE6C49CB8 wds:Q37203166-F2E792AF-B96B-44CF-BA3D-434027760AFC wds:Q37203166-FF9F380B-38BC-4ECE-AC3C-B5E46634B187
cites work	DNA methylation represses FMR-1 transcription in fragile X syndrome Structure and ligand of a histone acetyltransferase bromodomain Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins Histone H3 lysine 9 methylation is an epigenetic imprint of facultative heterochromatin. The structure of mouse HP1 suggests a unique mode of single peptide recognition by the shadow chromo domain dimer Requirement of CHROMOMETHYLASE3 for maintenance of CpXpG methylation Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome Regulation of chromatin structure by site-specific histone H3 methyltransferases Rb targets histone H3 methylation and HP1 to promoters Role of DNA methylation in the regulation of transcription Translational suppression by trinucleotide repeat expansion at FMR1. DNA methylation is linked to deacetylation of histone H3, but not H4, on the imprinted genes Snrpn and U2af1-rs1. Synergistic effect of histone hyperacetylation and DNA demethylation in the reactivation of the FMR1 gene. Analysis of a CGG sequence at the FMR-1 locus in fragile X families and in the general population Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription A simple salting out procedure for extracting DNA from human nucleated cells Translating the Histone Code Correlation between histone lysine methylation and developmental changes at the chicken beta-globin locus Acetylated histones are associated with FMR1 in normal but not fragile X-syndrome cells. The language of covalent histone modifications Methylation of histone H3 at lysine 4 is highly conserved and correlates with transcriptionally active nuclei in Tetrahymena Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex Structure and function of a human TAFII250 double bromodomain module Variation of the CGG repeat at the fragile X site results in genetic instability: Resolution of the Sherman paradox The FMR-1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation Absence of expression of the FMR-1 gene in fragile X syndrome Mapping of DNA instability at the fragile X to a trinucleotide repeat sequence p(CCG)n Differentially methylated forms of histone H3 show unique association patterns with inactive human X chromosomes Gene silencing. Methylation meets acetylation. A histone H3 methyltransferase controls DNA methylation in Neurospora crassa High resolution methylation analysis of the FMR1 gene trinucleotide repeat region in fragile X syndrome In vitro reactivation of the FMR1 gene involved in fragile X syndrome Parent-specific complementary patterns of histone H3 lysine 9 and H3 lysine 4 methylation at the Prader-Willi syndrome imprinting center The mojo of methylation Nuclease sensitivity of permeabilized cells confirms altered chromatin formation at the fragile X locus
author name string	wds:Q37203166-AE6C3D5E-80DE-4ACC-BB2C-B3AA389AB624 wds:Q37203166-D40A56A9-9A77-4982-853E-FD74746287D0 wds:Q37203166-F86FC10E-D378-480E-A30E-B40C96D71B1F
author name string	Bradford Coffee Fuping Zhang Daniel Reines
rdfs:label	Histone modifications depict an aberrantly heterochromatinized FMR1 gene in fragile x syndrome (en)

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