About: Integrated phosphoproteomic and metabolomic profiling reveals NPM-ALK-mediated phosphorylation of PKM2 and metabolic reprogramming in anaplastic large cell lymphoma.

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About: Integrated phosphoproteomic and metabolomic profiling reveals NPM-ALK-mediated phosphorylation of PKM2 and metabolic reprogramming in anaplastic large cell lymphoma. Goto Sponge NotDistinct Permalink

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scientific article published on 27 June 2013

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rdf:type	Item
description	videnskabelig artikel (da) article científic (ca) articolo scientifico (it) artigo científico (pt) bilimsel makale (tr) vedecký článok (sk) vetenskaplig artikel (sv) vědecký článek (cs) wetenschappelijk artikel (nl) wissenschaftlicher Artikel (de) научни чланак (sr) article scientifique (fr) artículu científicu espublizáu en 2013 (ast) наукова стаття, опублікована в червні 2013 (uk) مقالة علمية نشرت في 27 يونيو 2013 (ar) scientific article published on 27 June 2013 (en)
publication date	wds:Q37083961-037EA6CD-541E-4077-BF22-B331B73ACAED
publication date	2013-06-27 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q37083961-3AD90678-9BD2-4AA3-82A7-1F7CDC0DC8F5
language of work or name	English
cites work	wds:Q37083961-00FBD549-6E5A-403B-868F-69AD33FA5452 wds:Q37083961-12759AD1-7DB1-4EB9-8935-F5640D0080E9 wds:Q37083961-14879C88-C3E9-4C81-B1B5-2D1E378C39E2 wds:Q37083961-1788630C-63A9-4273-8260-3764012A20C0 wds:Q37083961-1AC474EE-1607-489A-92DE-1747A75875D7 wds:Q37083961-25ED11C3-8A30-443A-8702-7E7E8884CD6D wds:Q37083961-28D84B43-36D3-45BE-808C-EBD1FA55F97B wds:Q37083961-2F89BF28-DF14-4A8C-9106-E94147C43C03 wds:Q37083961-3253F4BF-D8AD-47AE-9CB0-F0708ACDD462 wds:Q37083961-328F3C92-604F-4137-AB02-CE230A87B878 wds:Q37083961-36F1037E-D19C-4441-AAAC-CD888B45E671 wds:Q37083961-3CCF7152-1F4A-4CAC-A031-F19003DD688B wds:Q37083961-3DB95928-F56E-4B56-B642-451C1D85C468 wds:Q37083961-40AFDF3D-1AE3-4033-8184-0B8E3F89E5EE wds:Q37083961-5C5D5A67-6B67-4DF1-A283-28593987CFE0 wds:Q37083961-6DEF14BD-FE64-4B6B-94D9-D94C3E2B2856 wds:Q37083961-6E9CE6E0-4066-4F57-B6D5-F322D888193B wds:Q37083961-7135E395-A49B-47AE-9E0D-A52B4D991019 wds:Q37083961-807152EC-C6CE-45D7-8DFF-6A3C3AEE7B1C wds:Q37083961-81528A10-D40A-4003-8510-AA1BDACF4DAB wds:Q37083961-824C8B19-C70C-472C-9630-8671F3F5FA55 wds:Q37083961-856C5FAC-C507-471B-8A24-55BCAB6B22C7 wds:Q37083961-9716FB7B-5AF5-4FF7-A525-1D693ADEB3EE wds:Q37083961-9F62A649-4CFB-434A-B7C0-DDF3ACE6D85C wds:Q37083961-A181A675-C283-47DC-92E9-A0CF1A04994A wds:Q37083961-A392861D-2107-4C81-8CC9-F871FE59144E wds:Q37083961-A46AA76A-88A8-458A-ABA4-FD8334CFA2C4 wds:Q37083961-A66069F8-60FA-489E-8205-88F900CF3E88 wds:Q37083961-A8AD7EE6-C1FF-49D4-BE27-8D7989946543 wds:Q37083961-B3DD4767-5803-4954-91BF-7BDD7E9396DF wds:Q37083961-B60CCD68-B830-44CF-8F95-61D3609C6C49 wds:Q37083961-DD108C5F-C07C-4419-A7FA-D63D3D143C60 wds:Q37083961-E3EDE2B3-FA4E-40B6-AEF6-757D5526A80C wds:Q37083961-E66C764A-6090-4555-9DFB-1AE00F9753D3 wds:Q37083961-E7003B8C-8187-419C-94BA-33863CDA0669 wds:Q37083961-ECFBD571-FE27-4A84-88EA-99FD23C30D75 wds:Q37083961-F7FA3952-28B7-4E93-9367-B3CBD424FA22 wds:Q37083961-FBA6D6FC-AD36-433C-9FC0-BB586A1B52A7 wds:Q37083961-FDBA578D-0217-4478-8401-F14116810595
cites work	Hallmarks of Cancer: The Next Generation KEGG: Kyoto Encyclopedia of Genes and Genomes ANTIBIOTIC STUDIES. II. INHIBITION OF PHOSPHORYL TRANSFER IN MITOCHONDRIA BY OLIGOMYCIN AND AUROVERTIN Phosphoglycerate Mutase 1 Coordinates Glycolysis and Biosynthesis to Promote Tumor Growth Aerobic glycolysis: meeting the metabolic requirements of cell proliferation Role of the nucleophosmin (NPM) portion of the non-Hodgkin's lymphoma-associated NPM-anaplastic lymphoma kinase fusion protein in oncogenesis Nucleophosmin-anaplastic lymphoma kinase of large-cell anaplastic lymphoma is a constitutively active tyrosine kinase that utilizes phospholipase C-gamma to mediate its mitogenicity Cytoreductive antitumor activity of PF-2341066, a novel inhibitor of anaplastic lymphoma kinase and c-Met, in experimental models of anaplastic large-cell lymphoma Pathobiology of ALK+ anaplastic large-cell lymphoma Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma Identification of NPM-ALK interacting proteins by tandem mass spectrometry. Role of phosphatidylinositol 3-kinase-Akt pathway in nucleophosmin/anaplastic lymphoma kinase-mediated lymphomagenesis Selective inhibition of STAT3 induces apoptosis and G(1) cell cycle arrest in ALK-positive anaplastic large cell lymphoma Recurrent involvement of 2p23 in inflammatory myofibroblastic tumors Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer Tyrosine phosphorylation of mitochondrial pyruvate dehydrogenase kinase 1 is important for cancer metabolism MetaboAnalyst: a web server for metabolomic data analysis and interpretation Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis Tyrosine phosphorylation of lactate dehydrogenase A is important for NADH/NAD(+) redox homeostasis in cancer cells Pyruvate kinase M2 is a phosphotyrosine-binding protein The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth KEGG for integration and interpretation of large-scale molecular data sets Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists Stat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target c-Myc transactivation of LDH-A: implications for tumor metabolism and growth Pyruvate kinase M2 promotes de novo serine synthesis to sustain mTORC1 activity and cell proliferation. THE METABOLISM OF TUMORS IN THE BODY Small Molecule Activation of PKM2 in Cancer Cells Induces Serine Auxotrophy Therapeutic strategies to overcome crizotinib resistance in non-small cell lung cancers harboring the fusion oncogene EML4-ALK. MetaboAnalyst 2.0--a comprehensive server for metabolomic data analysis NPM-ALK signals through glycogen synthase kinase 3β to promote oncogenesis Discovery of a potent inhibitor of anaplastic lymphoma kinase with in vivo antitumor activity The proteomic signature of NPM/ALK reveals deregulation of multiple cellular pathways. Allogeneic haematopoietic stem cell transplantation in relapsed or refractory anaplastic large cell lymphoma of children and adolescents--a Berlin-Frankfurt-Münster group report. The ATP assay is more sensitive than the succinate dehydrogenase inhibition test for predicting cell viability
author name string	wds:Q37083961-0CD3E07A-1872-45DF-AF6B-979FBDB43AB2

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