About: HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion.

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About: HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion. Goto Sponge NotDistinct Permalink

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scientific article published on 30 June 2008

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rdf:type	Item
description	videnskabelig artikel (da) article científic (ca) articolo scientifico (it) artigo científico (pt) bilimsel makale (tr) vedecký článok (sk) vetenskaplig artikel (sv) vědecký článek (cs) wetenschappelijk artikel (nl) wissenschaftlicher Artikel (de) научни чланак (sr) article scientifique (fr) artículu científicu espublizáu en 2008 (ast) наукова стаття, опублікована в червні 2008 (uk) مقالة علمية نشرت في 30 يونيو 2008 (ar) scientific article published on 30 June 2008 (en) 2008 ജൂണ്‍ 30 നു പ്രസിദ്ധീകരിച്ച ശാസ്ത്ര ലേഖനം (ml)
publication date	wds:Q37015151-EDA6A503-2DF3-4A4A-AD61-EA4FFF979369
publication date	2008-06-30 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q37015151-187537E1-E2D0-4781-9E0D-7D756BC7411D
language of work or name	English
exact match	wds:Q37015151-81D19001-D336-4E03-89DF-A63CD831151E
exact match	https://scigraph.springernature.com/pub.10.1038/onc.2008.207
cites work	wds:Q37015151-142F13F4-002D-4A03-90CE-8B8A96707EC7 wds:Q37015151-2048F202-48AC-405B-846F-225030CF872E wds:Q37015151-2FD27E52-7BE7-461D-AA9B-3FCB0CD96FE6 wds:Q37015151-40DD14B4-F820-4339-847B-DC65C8C211AA wds:Q37015151-4425833A-EEFA-43BF-90F0-702FC9EDCDAD wds:Q37015151-452343C5-D68E-41A1-BC79-D36E9A27265D wds:Q37015151-462024E4-6A20-4438-8EC1-43864E9864D0 wds:Q37015151-4E5BBA3B-A57C-462C-8945-9F7DB401EA35 wds:Q37015151-59BC09AF-999A-4CBB-AEC8-7D4C2913DDD0 wds:Q37015151-5F77895A-9053-4ABE-96FB-74199CA03F73 wds:Q37015151-64E744DD-0BB1-4F42-AEB2-CE000535B923 wds:Q37015151-6F33AC1C-16E0-4DB8-9CD9-99A91CC82A32 wds:Q37015151-8393F692-28F5-4CC2-8298-86D928911DD3 wds:Q37015151-8C1AF0D1-5691-4082-859B-E5FCBA9B5662 wds:Q37015151-95DCFC04-06D7-4537-A3B3-AD880DFA367A wds:Q37015151-9772902C-ED50-4C0A-86B9-32E8080C2410 wds:Q37015151-985FCEAA-54BC-4B14-BFFA-1A9E92FCCC05 wds:Q37015151-AC0E4740-ABF6-4EEF-A881-76839A61470A wds:Q37015151-B35AB7BA-5F7F-4A95-8B69-CA47AD92061E wds:Q37015151-BBF3DFA2-A2E1-4CBB-9F8A-D0619E56254A wds:Q37015151-C15C1ECF-6AB8-4D3F-89C6-3CCF86927A71 wds:Q37015151-C6B49832-BCF4-4FE7-9ECB-2E380B76024B wds:Q37015151-D7CBD1B2-5AB4-401D-90F7-ADDB249DD4A8 wds:Q37015151-D9B2D8BF-5BF6-4DB3-949B-203B56825499 wds:Q37015151-DAB1C3BB-B04F-4B20-9722-616E72E54EF6 wds:Q37015151-DAFBB605-7B82-4C6F-8C00-26A9A44C262D wds:Q37015151-DBB01766-5C95-4D73-B2FC-545540CBBB1D wds:Q37015151-E10B650D-DE91-4AD9-A557-1CC3F389A2C4 wds:Q37015151-E2C21BE3-BF62-40E1-9E84-618953CE783A wds:Q37015151-E5D62D10-A6A9-44AF-97B9-785B1DD63281 wds:Q37015151-F48890FF-0348-42B6-8EBD-DB8A38EFFC59
cites work	ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome Phosphoinositide 3-kinases and regulation of embryonic stem cell fate Characterization of a novel cell line established from a patient with Herceptin-resistant breast cancer. Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients. A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer Weekly trastuzumab and paclitaxel therapy for metastatic breast cancer with analysis of efficacy by HER2 immunophenotype and gene amplification. Pathologic findings from the National Surgical Adjuvant Breast and Bowel Project: prognostic significance of erbB-2 protein overexpression in primary breast cancer Immunohistochemical studies of early breast cancer evolution Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells Phenotypic and functional characterization in vitro of a multipotent epithelial cell present in the normal adult human breast. Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity. HER2/PI-3K/Akt activation leads to a multidrug resistance in human breast adenocarcinoma cells. Prospective identification of tumorigenic breast cancer cells Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway. Clinical activity of trastuzumab and vinorelbine in women with HER2-overexpressing metastatic breast cancer Cancer stem cells: an old idea--a paradigm shift CD44+/CD24- breast cancer cells exhibit enhanced invasive properties: an early step necessary for metastasis Dasatinib, an orally active small molecule inhibitor of both the src and abl kinases, selectively inhibits growth of basal-type/"triple-negative" breast cancer cell lines growing in vitro In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy The response of CD24(-/low)/CD44+ breast cancer-initiating cells to radiation Selective targeting of cancer stem cells: a new concept in cancer therapeutics Amplification of Her-2/neu gene in Her-2/neu-overexpressing and -nonexpressing breast carcinomas and their synchronous benign, premalignant, and metastatic lesions detected by FISH in archival material Celecoxib analogues disrupt Akt signaling, which is commonly activated in primary breast tumours Fbx15 is a novel target of Oct3/4 but is dispensable for embryonic stem cell self-renewal and mouse development HER2 status in pure ductal carcinoma in situ and in the intraductal and invasive components of invasive ductal carcinoma determined by fluorescence in situ hybridization and immunohistochemistry. The role of ErbB inhibitors in trastuzumab resistance [Herceptin, a monoclonal humanized antibody anti-HER2: a major therapeutic progress in breast cancers overexpressing this oncogene?]
author name string	wds:Q37015151-2D4F2989-7147-4728-ACEF-97933587453E wds:Q37015151-CE714A8B-333F-47B7-9FCD-0AB3A2905F0E
author name string	M S Wicha H Korkaya
rdfs:label	HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion. (en) HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion. (nl) HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion. (ast)
skos:prefLabel	HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion. (en) HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion. (nl) HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion. (ast)
name	HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion. (en) HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion. (nl) HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion. (ast)
author	wds:Q37015151-0B011862-4663-4A33-8F78-A3477416C50F

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