About: A central role for JNK in obesity and insulin resistance

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About: A central role for JNK in obesity and insulin resistance Goto Sponge NotDistinct Permalink

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scientific article (publication date: 21 November 2002)

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rdf:type	Item
description	artículu científicu espublizáu en 2002 (ast) наукова стаття, опублікована в листопаді 2002 (uk) 2002 թվականի նոյեմբերին հրատարակված գիտական հոդված (hy) 2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած (hyw) wetenschappelijk artikel (gepubliceerd op 2002/11/21) (nl) مقالة علمية (نشرت في 21-11-2002) (ar) article publié dans la revue scientifique Nature (fr) im November 2002 veröffentlichter wissenschaftlicher Artikel (de) scientific article (publication date: 21 November 2002) (en)
publication date	wds:Q29619778-5BD34B8E-0128-449E-9906-32A934771DF4
publication date	2002-11-21 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q29619778-0E8957A9-E6FD-45A6-A495-D9FC5A8E2CFA
language of work or name	English
cites work	wds:Q29619778-21764025-EC58-4D32-AE96-039C451F88E4 wds:Q29619778-25FEABCE-6094-4484-B655-2495B8992E6D wds:Q29619778-28550C6F-D127-4DF8-B516-90C62BE63CEC wds:Q29619778-29DC9541-C6F5-4AC5-9490-53A5A856CBF0 wds:Q29619778-2FB8B587-D215-44C8-A3BC-22E705A32474 wds:Q29619778-359059CE-73A8-4C07-B26E-093593730F75 wds:Q29619778-44C477CB-BE21-4AEB-90B0-21A75A16441E wds:Q29619778-7671B18D-AF4E-42A2-83F9-4D41EE51358A wds:Q29619778-79387FC4-103E-4E54-B3E7-736E028B696C wds:Q29619778-981FA8F7-859F-47A2-89C5-010137B4FC9D wds:Q29619778-9DA5117F-383E-4018-91AB-D03EE54AB318 wds:Q29619778-9F021798-5EEC-4D52-A584-241F6E774C32 wds:Q29619778-A04C608C-7765-4A83-99D3-42937B9AAD38 wds:Q29619778-B7DEB381-EAF0-4B11-8B91-4ABB50ABA574 wds:Q29619778-BC7B803B-C5EA-4C48-A31A-A07A06DBEAF5 wds:Q29619778-BCFD7108-2A63-4D07-AD7E-E0C6288B76C6 wds:Q29619778-C9BDA38F-0159-4F36-B38E-A09E058C0137 wds:Q29619778-D16DFD74-0758-4268-86B0-6659A3D43E7B wds:Q29619778-D39F7737-1C5C-41CE-9024-E4D0BC34912C wds:Q29619778-EA26B7D5-789F-4C21-A4B0-6264AAC29091 wds:Q29619778-EBCB3115-4041-4EF1-8A7C-E73F5F68CC0C wds:Q29619778-EF616FF5-0467-4627-9FC2-9D7D9A4AF442 wds:Q29619778-F3589C1A-D665-4944-B54F-C9305B8204D1 wds:Q29619778-FF9179ED-A68D-49A9-B478-5DBE8CECED20 wds:Q29619778-FFD4846F-30A2-45DE-9C2D-C08114BC19DB
cites work	Insulin signalling and the regulation of glucose and lipid metabolism Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade c-Jun NH2-terminal kinase (JNK)1 and JNK2 have similar and stage-dependent roles in regulating T cell apoptosis and proliferation JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development. Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain Sounding the alarm: protein kinase cascades activated by stress and inflammation Signal transduction by the JNK group of MAP kinases The adipocyte-secreted protein Acrp30 enhances hepatic insulin action The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity The hormone resistin links obesity to diabetes Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance Role of fatty acids in the pathogenesis of insulin resistance and NIDDM. Mammalian MAP kinase signalling cascades The role of TNF alpha in adipocyte metabolism. SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307) The gene MAPK8IP1, encoding islet-brain-1, is a candidate for type 2 diabetes The disease burden associated with overweight and obesity Defective T Cell Differentiation in the Absence of Jnk1 Cellular mechanisms of insulin resistance Arachidonic acid induces mobilization of calcium stores and c-jun gene expression: evidence that intracellular calcium release is associated with c-jun activation Improved Glucose and Lipid Metabolism in Genetically Obese Mice Lacking aP2 A cysteine-rich adipose tissue-specific secretory factor inhibits adipocyte differentiation Arachidonic acid induces the activation of the stress-activated protein kinase, membrane ruffling and H2O2 production via a small GTPase Rac1.
author name string	wds:Q29619778-4AB5FDB2-11C7-4375-A65E-905B9A4B8A54 wds:Q29619778-6145F65B-7C53-4509-877E-7E8C0760DAB0 wds:Q29619778-91F0A702-34A4-4D22-B03E-DAE4C26079C1 wds:Q29619778-9C824A94-3D71-4225-89C7-2AABB6452585 wds:Q29619778-B60F7EE4-4F1F-455C-B1C2-4BAA62E72153 wds:Q29619778-C16C46D7-BCB1-48DB-8A35-DBABF58C46D1 wds:Q29619778-E7584BB5-AD40-4C30-ACC3-D1C34C8624DD
OpenCitations bibliographic resource ID	wds:Q29619778-419D0724-09C9-4636-94FD-AA2B3C3F6DBA
OpenCitations bibliographic resource ID	https://w3id.org/oc/corpus/br/124977
author name string	Karin M Chang L Maeda K Görgün CZ Uysal KT Hirosumi J Tuncman G
OpenCitations bibliographic resource ID	124977
rdfs:label	A central role for JNK in obesity and insulin resistance (en) A central role for JNK in obesity and insulin resistance (ast)
skos:prefLabel	A central role for JNK in obesity and insulin resistance (en) A central role for JNK in obesity and insulin resistance (ast)
name	A central role for JNK in obesity and insulin resistance (en) A central role for JNK in obesity and insulin resistance (ast)
author	wds:Q29619778-D596B59F-0BB8-478C-896E-9285CB6EEE34
author	Gökhan Hotamışlıgil
title	wds:Q29619778-DF56295C-19CF-4927-BECE-FFD2931F711F
title	A central role for JNK in obesity and insulin resistance (en)
page(s)	wds:Q29619778-E7B30EA3-B468-4882-B526-19DE37D8FA55
page(s)	333-6
instance of	wds:Q29619778-F11EF84D-8515-4E29-A5EC-816DE52D16BF
instance of	scholarly article
main subject	wds:Q29619778-01CAAC5A-B15C-451A-A99A-FDD70C9EE75A wds:Q29619778-B97D06B6-029F-4F0A-A1BE-F0CA06FCA274 wds:Q29619778-F6F19EF7-1113-4020-826F-74B771390C62
main subject	insulin resistance wd:Q7240673

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