About: Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity Goto Sponge NotDistinct Permalink

An Entity of Type : wikibase:Item, within Data Space : wikidata.demo.openlinksw.com associated with source document(s)

scientific article (publication date: July 2008)

Attributes	Values
rdf:type	Item
description	article scientifique publié en 2008 (fr) artículu científicu espublizáu en 2008 (ast) наукова стаття, опублікована в липні 2008 (uk) 2008 թվականի հուլիսին հրատարակված գիտական հոդված (hy) 2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած (hyw) wetenschappelijk artikel (gepubliceerd in 2008-07) (nl) مقالة علمية (نشرت في يوليو 2008) (ar) scientific article (publication date: July 2008) (en) im Juli 2008 veröffentlichter wissenschaftlicher Artikel (de)
publication date	wds:Q29618117-F568ED9C-165A-40E5-B229-2B45E6B89332
publication date	2008-07-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q29618117-CF3DA810-5692-424C-9425-3850875A1159
language of work or name	English
cites work	wds:Q29618117-3F1A797D-1ED5-4A5A-81B9-E154FD78F6B4
cites work	Mutant PIK3CA promotes cell growth and invasion of human cancer cells
author name string	wds:Q29618117-28344B54-A635-406C-A943-04E79901DE61 wds:Q29618117-2AC20D63-5A77-4F5E-97C6-44E5CA1835B5 wds:Q29618117-345E038E-E341-467E-BD5D-E38171934F42 wds:Q29618117-369A0237-5356-40A0-A3FF-C8DDEBCAB01B wds:Q29618117-5F87548F-BBBE-4E12-86AB-4F3B10E40F99 wds:Q29618117-7310D3E7-DB7A-403D-91B3-03D55FD2DE08 wds:Q29618117-7962CCC2-EB31-4617-821E-0E6899F54AE0 wds:Q29618117-82A3C5A0-0F85-453F-A7CD-F008901E4932 wds:Q29618117-84754CFA-5B75-4ABD-8E83-E4E2D148FD14 wds:Q29618117-85924E33-E96A-406F-9F67-FCC2C2F64A64 wds:Q29618117-89052A09-4715-413E-AF47-757FC427EDC2 wds:Q29618117-8BDC5E21-2BC2-478D-B875-4B05D7DE8F86 wds:Q29618117-9143CB89-A7AA-41E3-AE2B-7F99B6A82FDF wds:Q29618117-91E9BA51-6791-4E2B-BF8F-22868BDE2F88 wds:Q29618117-DC38A175-2333-462A-899A-F28B7806928F wds:Q29618117-E9A6C819-EC5B-45D7-9F30-F885FF87D286 wds:Q29618117-EDBD1C94-1963-43DE-A087-CB4C1EC6814B
OpenCitations bibliographic resource ID	wds:Q29618117-3F542559-34F2-44CD-A73A-3B7796D4D46D
OpenCitations bibliographic resource ID	https://w3id.org/oc/corpus/br/1572545
author name string	Schnell C Gabriel D Murphy L Finan P Furet P García-Echeverría C Fabbro D De Pover A Stauffer F Simonen M Sellers W Fritsch C Maira SM Chène P Brachmann S Brueggen J Schoemaker K
OpenCitations bibliographic resource ID	1572545
rdfs:label	Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity (en) Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity (ast)
skos:prefLabel	Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity (en) Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity (ast)
name	Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity (en) Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity (ast)
title	wds:Q29618117-262493A0-0509-4F7A-BA8B-375155091A0E
title	Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity (en)
page(s)	wds:Q29618117-CD591DF5-BFF0-42C6-A2C0-B62491E8C6FF
page(s)	1851-63
instance of	wds:Q29618117-4476C053-05EB-4BF6-B94A-2BBA9277E9E5
instance of	scholarly article
main subject	wds:Q29618117-71947657-DC01-44DD-AA8A-72DB4ED94DED
main subject	sirolimus
PubMed ID	wds:Q29618117-625843F8-866E-4FBA-B46F-FB6D63DA9A2C
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/18606717
PubMed ID	18606717
published in	wds:Q29618117-A38ED83F-BF10-4861-AD95-BBDD2C24E410
published in	Molecular Cancer Therapeutics
issue	wds:Q29618117-AAE4036B-47D6-4743-800F-5BE6534C3E1A
volume	wds:Q29618117-35973F5A-1EA0-4D9E-B7DC-C56C2515147D
issue	7
volume	7
DOI	wds:Q29618117-A7C6D40D-E248-4357-BEB3-C75CCB9CFBFF
DOI	http://dx.doi.org/10.1158/1535-7163.MCT-08-0017
DOI	10.1158/1535-7163.MCT-08-0017
ResearchGate publication ID	wds:Q29618117-F2E94937-5E3B-4C69-8073-5C4E88C6B401
ResearchGate publication ID	5245712
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q29618117
is cites work of	Pancreatic endocrine tumors: expression profiling evidences a role for AKT-mTOR pathway Aberrant AKT activation drives well-differentiated liposarcoma Targeting the PI3K/Akt/mTOR pathway--beyond rapalogs Increased AKT S473 phosphorylation after mTORC1 inhibition is rictor dependent and does not predict tumor cell response to PI3K/mTOR inhibition PI3K/AKT/mTOR Pathway in Angiogenesis Discovery of 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one as a highly potent, selective mammalian target of rapamycin (mTOR) inhibitor for the treatment of cancer Targeting the mTOR kinase domain: the second generation of mTOR inhibitors Principles of cancer therapy: oncogene and non-oncogene addiction Enhancing mTOR-targeted cancer therapy Antitumor activities of ATP-competitive inhibitors of mTOR in colon cancer cells Efficacy of the investigational mTOR kinase inhibitor MLN0128/INK128 in models of B-cell acute lymphoblastic leukemia Targeting Phosphatidylinositide3-Kinase/Akt pathway by BKM120 for radiosensitization in hepatocellular carcinoma Dual activity lysophosphatidic acid receptor pan-antagonist/autotaxin inhibitor reduces breast cancer cell migration in vitro and causes tumor regression in vivo In vitro multifaceted activities of a specific group of novel phosphatidylinositol 3-kinase inhibitors on hotspot mutant PIK3CA. Identification of NVP-BKM120 as a Potent, Selective, Orally Bioavailable Class I PI3 Kinase Inhibitor for Treating Cancer Effectiveness of combined treatment using X-rays and a phosphoinositide 3-kinase inhibitor, ZSTK474, on proliferation of HeLa cells in vitro and in vivo Rapamycin regulates stearoyl CoA desaturase 1 expression in breast cancer Synergistic potentiation of (-)-lomaiviticin A cytotoxicity by the ATR inhibitor VE-821.

Faceted Search & Find service v1.16.117 as of May 05 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3239 as of May 5 2024, on Linux (x86_64-centos_6-linux-gnu), Single-Server Edition (378 GB total memory, 194 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software