About: Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

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About: Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice Goto Sponge NotDistinct Permalink

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rdf:type	Item
description	artículu científicu espublizáu en 1994 (ast) vědecký článek publikovaný v roce 1994 (cs) 1994 թվականի մայիսին հրատարակված գիտական հոդված (hy) 1994 թուականի Մայիսին հրատարակուած գիտական յօդուած (hyw) наукова стаття, опублікована в травні 1994 (uk) article publié dans la revue scientifique Nature (fr) scientific journal article (en) im Mai 1994 veröffentlichter wissenschaftlicher Artikel (de) wetenschappelijk artikel (gepubliceerd op 1994/05/05) (nl) vedecký článok (publikovaný 1994/05/05) (sk) مقالة علمية (نشرت في 5-5-1994) (ar)
publication date	wds:Q28594763-B1BDD531-16CA-497D-B69D-1173C09F7789
publication date	1994-05-05 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28594763-92608848-98BB-462A-A427-D120574A1F41
language of work or name	English
cites work	wds:Q28594763-05DA6EF9-5133-48E0-B9F1-ED14D25120BF wds:Q28594763-06429E35-0E74-4537-9CD9-9073DE536B35 wds:Q28594763-09A1C931-E887-4DF7-9639-6BB5AC921A9B wds:Q28594763-2C110081-4646-43C0-B148-1FFFB9CC9472 wds:Q28594763-311E8ADA-BE83-4AF0-9A81-A2F84DF635A5 wds:Q28594763-33DAD4D5-0A27-49CE-835B-9B87EC0AFFED wds:Q28594763-3639C338-1D90-4333-ABDE-633BF5DB4C77 wds:Q28594763-3677900C-D0F0-4470-B206-A5E9D6456931 wds:Q28594763-50BF6C20-E590-470B-92F3-CF77DF9CA8FA wds:Q28594763-5A7262B1-2CBB-4C21-AFE7-91372A726D85 wds:Q28594763-5D55D78D-6646-4571-BAD4-B4C0D4316EFF wds:Q28594763-6414E546-8804-43FD-84AF-E2BDCCD66629 wds:Q28594763-6B6DE8BE-2800-4EDF-953F-BFD8B95CAEA4 wds:Q28594763-7B47D4FD-D0FB-4D0D-B073-1E1972A00859 wds:Q28594763-80E3A76D-414D-43E6-BEC3-ADB743903510 wds:Q28594763-8152E568-D96A-43F5-BAAB-45DCB412068E wds:Q28594763-8A4B068B-2FDA-4B30-AFC1-2F32A2CBA4B8 wds:Q28594763-8D643C26-B1B8-49BE-956B-9EFA60FF269D wds:Q28594763-92D09698-AE23-4AB2-8CE5-24FAD7608E23 wds:Q28594763-944C7447-166E-4F7E-A325-91428F6AC30F wds:Q28594763-A0A98B3A-D72D-4F38-B13D-833FAFFA7A74 wds:Q28594763-A234D488-D352-445A-8093-692E2235E19A wds:Q28594763-A9D094BA-634C-45D3-ADEE-F63AA4CD5722 wds:Q28594763-AFB30D20-BF84-42C6-B128-FC6E10C1116B wds:Q28594763-BF60FAA7-B074-4722-862A-F8AD6918BF7B wds:Q28594763-C2A1596F-7B35-421A-A9D0-0B0FAD0DE60F wds:Q28594763-CE8CF9B9-2E44-446C-B124-6F553B91DD3D wds:Q28594763-D325B09A-5847-4B1C-8F00-AD35D03A53EA wds:Q28594763-DE85B719-C5A8-4BB0-B1BB-4BF97DFFEC09 wds:Q28594763-DFBF6E86-D295-4861-8D99-E5B8CBB71E37 wds:Q28594763-E19E9145-A182-4EF8-805B-FD7225F42C39 wds:Q28594763-E886F514-F79D-4C1D-86B8-D31FC8635C74 wds:Q28594763-F22F4616-DCFF-463D-B56C-15A2BC2E365C wds:Q28594763-F351B977-D49E-4151-BA33-279E4F70E6E3 wds:Q28594763-F9210EDC-99B0-4433-A4B0-BB1C1ED49E92 wds:Q28594763-FBC354C1-FE40-404F-AFAA-68AA5AB89C9C
cites work	Therapy with monoclonal antibodies by elimination of T-cell subsets in vivo Expression of retroviral vectors in transgenic mice obtained by embryo infection Isolation and biochemical and functional characterization of perforin 1 from cytolytic T-cell granules Mechanism of lymphocyte-mediated cytotoxicity Cytolysis by H-2-specific T killer cells. Assembly of tubular complexes on target membranes Viral escape by selection of cytotoxic T cell-resistant virus variants in vivo Perforin-mediated myocardial damage in acute myocarditis Immune response in mice that lack the interferon-gamma receptor Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells Quantification of lymphocytic choriomeningitis virus with an immunological focus assay in 24- or 96-well plates Cytotoxicity with target DNA breakdown by rat basophilic leukemia cells expressing both cytolysin and granzyme A CTL: virus control cells first and cytolytic cells second? DNA fragmentation, apoptosis and the prelytic halt hypothesis Purification and characterization of a cytolytic pore-forming protein from granules of cloned lymphocytes with natural killer activity Granzymes, a family of serine proteases released from granules of cytolytic T lymphocytes upon T cell receptor stimulation Homology of perforin to the ninth component of complement (C9). Structure and function of human perforin Fas involvement in Ca(2+)-independent T cell-mediated cytotoxicity Establishment of a germ-line competent C57BL/6 embryonic stem cell line LCMV-specific, class II-restricted cytotoxic T cells in beta 2-microglobulin-deficient mice Expression of cytokines by recombinant vaccinia viruses: a model for studying cytokines in virus infections in vivo A high proportion of T lymphocytes that infiltrate H-2-incompatible heart allografts in vivo express genes encoding cytotoxic cell-specific serine proteases, but do not express the MEL-14-defined lymph node homing receptor. Internal Disintegration Model of Cytotoxic Lymphocyte-Induced Target Damage T cell-mediated hepatitis in mice infected with lymphocytic choriomeningitis virus. Liver cell destruction by H-2 class I-restricted virus-specific cytotoxic T cells as a physiological correlate of the 51Cr-release assay? Detection of perforin and granzyme A mRNA in infiltrating cells during infection of mice with lymphocytic choriomeningitis virus A central role of perforin in cytolysis? Recovery from acute virus infection. Role of cytotoxic T lymphocytes in the elimination of lymphocytic choriomeningitis virus from spleens of mice Genomic organization of the mouse pore-forming protein (perforin) gene and localization to chromosome 10. Similarities to and differences from C9. The molecular mechanism of lymphocyte-mediated tumor cell lysis Immune response against lymphocytic choriomeningitis virus infection in mice without CD8 expression Structure, function and expression of murine and human perforin 1 (P1). Expression of perforin in murine natural killer cells and cytotoxic T lymphocytes in vivo Enhanced tumor susceptibility of immunocompetent mice infected with lymphocytic choriomeningitis virus Structure of the mouse pore-forming protein (perforin) gene: analysis of transcription initiation site, 5' flanking sequence, and alternative splicing of 5' untranslated regions Virus-induced delayed-type hypersensitivity reaction is sequentially mediated by CD8+ and CD4+ T lymphocytes Distinct patterns of virus-specific T cell-mediated cytolysis of transformed versus primary target cells
author name string	wds:Q28594763-2DF71C70-BFF2-482B-A932-18BBE6A974D8 wds:Q28594763-549086A0-0507-4BCE-924A-D15604BF77CD wds:Q28594763-6117746E-F45E-4729-A634-DD77DFC4E1B6 wds:Q28594763-6CC7F513-F1AD-4E59-913D-6F9B5744BE2D wds:Q28594763-AA6D0B27-3BCD-4656-8AAB-F42D733C0636 wds:Q28594763-ACB69420-D4FA-4188-A406-58C23920A2F1 wds:Q28594763-CEA841C8-1EA6-4B53-ABEB-592417DB6EDA wds:Q28594763-FC25F60B-C8C8-43C5-93A4-E3C3F2975817
OpenCitations bibliographic resource ID	wds:Q28594763-E5A598E0-56F4-49F7-86CB-9EFFD4310D8D
OpenCitations bibliographic resource ID	https://w3id.org/oc/corpus/br/514561
author name string	H. Hengartner E. R. Podack

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