About: Dependence of self-tolerance on TRAF6-directed development of thymic stroma

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rdf:type	Item
description	наукова стаття, опублікована у квітні 2005 (uk) artículu científicu espublizáu en 2005 (ast) vědecký článek publikovaný v roce 2005 (cs) 2005 թվականի ապրիլին հրատարակված գիտական հոդված (hy) 2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած (hyw) vedecký článok (publikovaný 2005/04/08) (sk) wetenschappelijk artikel (gepubliceerd op 2005/04/08) (nl) im April 2005 veröffentlichter wissenschaftlicher Artikel (de) مقالة علمية (نشرت في 8-4-2005) (ar) article publié dans la revue scientifique Science (fr) scientific journal article (en)
publication date	wds:Q28590193-7E2AFABE-740B-4001-8751-6F7A01B99B5D
publication date	2005-04-08 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28590193-76D22521-F9FF-48E2-90C8-C65E2DE7AF23
language of work or name	English
author name string	wds:Q28590193-16648879-83B9-4C76-990C-CAEDD6DDB5F0 wds:Q28590193-21F5C3CB-341E-455E-913D-2300F1678B20 wds:Q28590193-7AC816EF-D01E-4D3F-BA9C-BCFBAD05E673 wds:Q28590193-892BEE9D-21B4-4B0E-A1C8-F96BB6726BA1 wds:Q28590193-8D0C6993-8FAF-4A76-B344-C644C1CA0168 wds:Q28590193-904F26D9-0719-4484-941D-8E0C84DD1570 wds:Q28590193-957220DA-5EB4-4447-B873-4CF0B29181A9 wds:Q28590193-B7A83574-E304-4497-9604-E5D1979622D3
OpenCitations bibliographic resource ID	wds:Q28590193-95B4AA98-48E1-4A45-BAF1-BE5F9B249A5C
OpenCitations bibliographic resource ID	https://w3id.org/oc/corpus/br/192169
author name string	Mitsuru Matsumoto Fumiko Kajiura Jun-ichiro Inoue Kaori Ogino Michiyuki Kasai Sayaka Yamane Shiori Maeda Taishin Akiyama
OpenCitations bibliographic resource ID	192169
rdfs:label	Dependence of self-tolerance on TRAF6-directed development of thymic stroma (en) Dependence of self-tolerance on TRAF6-directed development of thymic stroma (nl) Dependence of self-tolerance on TRAF6-directed development of thymic stroma (ast)
skos:prefLabel	Dependence of self-tolerance on TRAF6-directed development of thymic stroma (en) Dependence of self-tolerance on TRAF6-directed development of thymic stroma (nl) Dependence of self-tolerance on TRAF6-directed development of thymic stroma (ast)
name	Dependence of self-tolerance on TRAF6-directed development of thymic stroma (en) Dependence of self-tolerance on TRAF6-directed development of thymic stroma (nl) Dependence of self-tolerance on TRAF6-directed development of thymic stroma (ast)
title	wds:Q28590193-9F428F99-B36E-4488-B5D4-7A7F7F29F931
title	Dependence of self-tolerance on TRAF6-directed development of thymic stroma (en)
page(s)	wds:Q28590193-237C747D-12DA-4F6B-A75D-CC1945FB5294
page(s)	248–251
instance of	wds:Q28590193-C6578564-5159-4F91-A047-4DC4251E32F2
instance of	scholarly article
main subject	wds:Q28590193-8BEDB0A8-83FF-47C6-ABE2-22AE9576BEC4
main subject	TNF receptor-associated factor 6
PubMed ID	wds:Q28590193-14E86863-DB0D-4D55-9450-AC7C9A477196
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/15705807
PubMed ID	15705807
published in	wds:Q28590193-6550FF0E-D77C-4C39-979B-29043642788A
published in	Science
issue	wds:Q28590193-1936C63F-FDDE-4CFF-91B4-2D0FB0947B21
volume	wds:Q28590193-DE1E1067-BF16-451D-9E6C-FA782F9EBF34
issue	5719
volume	308
DOI	wds:Q28590193-27954F6F-E66A-4AB7-A04B-443EBCED5CBC
DOI	http://dx.doi.org/10.1126/SCIENCE.1105677
DOI	10.1126/SCIENCE.1105677
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q28590193
is cites work of	Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells T follicular helper cells during immunity and tolerance. Developmental regulation of Foxp3 expression during ontogeny. T-cell tolerance: central and peripheral Characterization of immune functions in TRAF4-deficient mice The roles of the classical and alternative nuclear factor-kappaB pathways: potential implications for autoimmunity and rheumatoid arthritis Thymic epithelial cell development and differentiation: cellular and molecular regulation Regulation of CD8+ T cell development by thymus-specific proteasomes Formation of a functional thymus initiated by a postnatal epithelial progenitor cell. Expression of the autoimmune regulator gene and its relevance to the mechanisms of central and peripheral tolerance Modulation of Aire regulates the expression of tissue-restricted antigens Regulation of medullary thymic epithelial cell differentiation and function by the signaling protein Sin. Direct and indirect roles of the LTbetaR pathway in central tolerance induction. NF-kappaB2 is required for the establishment of central tolerance through an Aire-dependent pathway NF-kappaB2 is required for the control of autoimmunity by regulating the development of medullary thymic epithelial cells Rank signaling links the development of invariant γδ T cell progenitors and Aire(+) medullary epithelium RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla Sequential phases in the development of Aire-expressing medullary thymic epithelial cells involve distinct cellular input Autoimmune regulator initiates the expression of promiscuous genes in thymic epithelial cells Ubiquitylation in innate and adaptive immunity. NF-kappaB activation in development and progression of cancer TRAF6 is a T cell-intrinsic negative regulator required for the maintenance of immune homeostasis Regulatory T cells exert checks and balances on self tolerance and autoimmunity Tumor necrosis factor receptor- associated factor 6 (TRAF6) regulation of development, function, and homeostasis of the immune system Medullary thymic epithelial cells expressing Aire represent a unique lineage derived from cells expressing claudin. Central tolerance: learning self-control in the thymus Establishment and functioning of intrathymic microenvironments. Thymic microenvironments for T cell differentiation and selection. Ubiquitin-dependent regulation of Foxp3 and Treg function Ubiquitin in the immune system TRAF6 directs commitment to regulatory T cells in thymocytes Thymic medullary epithelium and thymocyte self-tolerance require cooperation between CD28-CD80/86 and CD40-CD40L costimulatory pathways Thymic epithelial cells: antigen presenting cells that regulate T cell repertoire and tolerance development OX40 and CD30 signals in CD4(+) T-cell effector and memory function: a distinct role for lymphoid tissue inducer cells in maintaining CD4(+) T-cell memory but not effector function Transcriptional regulation by AIRE: molecular mechanisms of central tolerance

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