About: Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9

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scientific journal article

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rdf:type	Item
description	наукова стаття, опублікована у квітні 2005 (uk) artículu científicu espublizáu en 2005 (ast) vědecký článek publikovaný v roce 2005 (cs) 2005 թվականի ապրիլին հրատարակված գիտական հոդված (hy) 2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած (hyw) 2005年學術文章 (zh) im April 2005 veröffentlichter wissenschaftlicher Artikel (de) article publié dans les Proceedings of the National Academy of Sciences of the United States of America (fr) scientific journal article (en) vedecký článok (publikovaný 2005/04/12) (sk) wetenschappelijk artikel (gepubliceerd op 2005/04/12) (nl) مقالة علمية (نشرت في 12-4-2005) (ar)
publication date	wds:Q28588292-B3BFF313-78B9-4BCB-B585-78789CBD90B5
publication date	2005-04-12 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28588292-FF904C4C-1F2F-4D0C-975B-6B78CE3E5E74
language of work or name	English
cites work	wds:Q28588292-14741FFF-299C-4F8A-A2CE-A3C00FFDBB07 wds:Q28588292-22766E17-0033-4100-B56E-46D8E50FD954 wds:Q28588292-456836F3-80DF-4D7A-A198-C6B5AEF6DC09 wds:Q28588292-4FC5CB5F-EB2B-470E-8DDB-B35E0C37D401 wds:Q28588292-5B45852E-FCDD-420D-ABCF-33D5A3B6B9B9 wds:Q28588292-7B1DD662-7C50-4778-B882-C7E48C9CDD54 wds:Q28588292-7BA51FE6-76C7-4613-9AF0-71C2F0C027E2 wds:Q28588292-82D680C1-77D4-4A75-9C31-8A3A1190CEC9 wds:Q28588292-8EC77203-06B1-4BBC-8A68-3733D1AD8BFB wds:Q28588292-8F4BF7FB-F25A-4FBA-9877-587671BE00FB wds:Q28588292-A3E4945F-6144-473E-A583-AF89B93AF80E wds:Q28588292-A99BE399-94AE-4275-B12D-3E75540B9DC0 wds:Q28588292-AA70745A-B9F7-4F37-AFEC-5187F0349128 wds:Q28588292-C4D251B8-216C-4BF4-A4FC-CD1C6D20B284 wds:Q28588292-C6ED5F39-8C0F-4B3B-ABEA-41CE887587CE wds:Q28588292-C808B0E5-6D2D-4AF5-8DC0-C279C715A0EB wds:Q28588292-CDB25C51-E595-4C44-B86F-21A73DF07E0E wds:Q28588292-DA7C858E-00CB-4B40-B4EA-3485CFD6B153 wds:Q28588292-E0D6AF4B-158C-459E-A664-65E78D8FD3B6 wds:Q28588292-E9777938-F52F-4545-B173-BD6CA69B5A17 wds:Q28588292-EE6146DC-44B4-48E9-BDF0-16370A13123D wds:Q28588292-F0B74BBD-BE04-461F-AB2C-356E73A9F4E5 wds:Q28588292-F3CB24FD-9DB5-408A-84C5-D0B146C23D02 wds:Q28588292-F55106E9-F5CE-49D2-997D-EBB8200D8F2F wds:Q28588292-F6855287-1FD7-459F-AAA1-EFA78D691F52
cites work	Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a Role of liver in the maintenance of cholesterol and low density lipoprotein homeostasis in different animal species, including humans. The Low-Density Lipoprotein Pathway and its Relation to Atherosclerosis Disruption of LDL receptor gene in transgenic SREBP-1a mice unmasks hyperlipidemia resulting from production of lipid-rich VLDL SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver The role of the LDL receptor in apolipoprotein B secretion Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c Overexpression of Insig-1 in the livers of transgenic mice inhibits SREBP processing and reduces insulin-stimulated lipogenesis Decreased lipid synthesis in livers of mice with disrupted Site-1 protease gene The LDL receptor gene family: (un)expected signal transducers in the brain Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9. The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation Monogenic hypercholesterolemia: new insights in pathogenesis and treatment Mutations in PCSK9 cause autosomal dominant hypercholesterolemia Overexpression of PCSK9 accelerates the degradation of the LDLR in a post-endoplasmic reticulum compartment A mutation in PCSK9 causing autosomal-dominant hypercholesterolemia in a Utah pedigree Mutations in the PCSK9 gene in Norwegian subjects with autosomal dominant hypercholesterolemia Post-transcriptional regulation of low density lipoprotein receptor protein by proprotein convertase subtilisin/kexin type 9a in mouse liver. Adenoviral-mediated expression of Pcsk9 in mice results in a low-density lipoprotein receptor knockout phenotype Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery NARC-1/PCSK9 and its natural mutants: zymogen cleavage and effects on the low density lipoprotein (LDL) receptor and LDL cholesterol Novel putative SREBP and LXR target genes identified by microarray analysis in liver of cholesterol-fed mice Normal Sorting but Defective Endocytosis of the Low Density Lipoprotein Receptor in Mice with Autosomal Recessive Hypercholesterolemia Inhibitors of Cholesterol Biosynthesis Increase Hepatic Low-Density Lipoprotein Receptor Protein Degradation
author name string	wds:Q28588292-0EA2CBEC-6159-4DF5-BF23-316F6D1B62A6 wds:Q28588292-603E939A-BABB-4D43-8146-CC456504BB2B wds:Q28588292-6DE67B3F-A467-42A2-9253-88709BF9AC7B wds:Q28588292-77D7AC41-1188-47A5-8F45-2DCE3FAF93B5 wds:Q28588292-7CD7D34C-4C60-49A5-92D1-C23B98240A9C wds:Q28588292-892D9A7B-A562-4042-BC81-7113B147E517 wds:Q28588292-8BB058C0-EACA-4A63-B073-10189E4AE6B9 wds:Q28588292-D770ADE8-5D7B-437D-AED2-598BBB131AE5
OpenCitations bibliographic resource ID	wds:Q28588292-863B4263-F02F-4F8D-89B1-E8C9FA26358B
OpenCitations bibliographic resource ID	https://w3id.org/oc/corpus/br/899854
author name string	Robert E. Hammer Young-Ah Moon Rita Garuti Shirya Rashid Y. K. Ho David E. Curtis Norma N. Anderson Yuriy Bashmakov
OpenCitations bibliographic resource ID	899854
rdfs:label	Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9 (en) Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9 (nl) Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9 (ast)
skos:prefLabel	Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9 (en) Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9 (nl) Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9 (ast)
name	Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9 (en) Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9 (nl) Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9 (ast)
author	wds:Q28588292-4BA7D5A4-BEBA-4BCF-B7AA-27D6A83AAD91
author	Jay D Horton
title	wds:Q28588292-EADFC974-88B3-4054-A6A0-FB5EA8BD2E75
title	Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9 (en)
page(s)	wds:Q28588292-529FE184-A0BF-47A0-AA86-C6473D3E25CE

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