About: Over-expression of the glucagon-like peptide-1 receptor on INS-1 cells confers autocrine stimulation of insulin gene promoter activity: a strategy for production of pancreatic beta-cell lines for use in transplantation

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About: Over-expression of the glucagon-like peptide-1 receptor on INS-1 cells confers autocrine stimulation of insulin gene promoter activity: a strategy for production of pancreatic beta-cell lines for use in transplantation Goto Sponge NotDistinct Permalink

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scientific journal article

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rdf:type	Item
description	artículu científicu espublizáu en 2002 (ast) vědecký článek publikovaný v roce 2002 (cs) наукова стаття, опублікована в лютому 2002 (uk) 2002 թվականի փետրվարին հրատարակված գիտական հոդված (hy) 2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած (hyw) مقالة علمية (نشرت في فبراير 2002) (ar) vedecký článok (publikovaný 2002/02/01) (sk) wetenschappelijk artikel (gepubliceerd op 2002/02/01) (nl) article scientifique publié en 2002 (fr) im Februar 2002 veröffentlichter wissenschaftlicher Artikel (de) scientific journal article (en)
publication date	wds:Q28582687-58F104BC-A7E1-429F-9133-5F76FD27FAA4
publication date	2002-02-01 00:00:00Z (xsd:dateTime)
exact match	wds:Q28582687-5CF24B23-6F46-47AD-84D9-A83AF4593878
exact match	https://scigraph.springernature.com/pub.10.1007/s00441-001-0494-7
cites work	wds:Q28582687-0E65E167-8B3E-46BA-AED6-475B81C0C90A wds:Q28582687-1862B10E-6824-46BE-9BCF-EEB1942FDE92 wds:Q28582687-21E3AC5F-D87A-4B1A-BB8F-ABC8197A295F wds:Q28582687-2F14AFD8-4D56-40EC-B5BE-5B4B71A1C69F wds:Q28582687-328E9BEC-78F0-4F09-B2AC-29CEE6A2EF34 wds:Q28582687-35B2FF49-321F-4FE5-A91E-A4A73F464E34 wds:Q28582687-37A479A9-15A1-47A6-A463-27F84A013DFD wds:Q28582687-3F0AB6DD-E975-4125-B079-95C22E766519 wds:Q28582687-40CB21FC-C2A8-48A1-A03B-479101BC7195 wds:Q28582687-4345CF85-BD8B-4F0C-A04F-9DCDDE906076 wds:Q28582687-4A875185-94CD-4D0A-A48A-85E256193B4B wds:Q28582687-55A7F046-FC5B-468F-BD2A-5BB52612CF59 wds:Q28582687-5BC7E654-E1E8-48FE-966B-45DC8756C680 wds:Q28582687-669B78ED-2296-40A6-85E1-4D80ABF8E072 wds:Q28582687-66C41B47-2280-4F4B-A37E-C16179272E35 wds:Q28582687-7C48C22A-B3E9-44F8-A40D-71632D748D07 wds:Q28582687-8C46F2A9-846B-442F-9D08-36C41D1F9B47 wds:Q28582687-953463DB-F4A9-43F6-AFA3-7D207080D313 wds:Q28582687-A0360611-AC98-4D25-9CD9-FD7A0A106010 wds:Q28582687-A1E5AEB5-CA12-45B5-BA30-4F2DB363DABF wds:Q28582687-AE8B9730-D884-4175-A9E4-7919A71BA794 wds:Q28582687-B38C5AF9-68D8-44A8-8906-5552641FC3E5 wds:Q28582687-BFED0A1E-2A4B-48B9-A961-8E7AF1B4B295 wds:Q28582687-C02D56E7-E1C6-4A5E-AC9F-881C9F43A31C wds:Q28582687-C99DAFF7-9FD6-4538-AB6C-9C8EE5A9ACE0 wds:Q28582687-DB4DAA25-441B-4BA3-8676-548715232496 wds:Q28582687-E20D210F-9D15-4D84-84D4-BC3225632AEB wds:Q28582687-EAB1415E-3BF0-4A54-B210-4632EEC7892D wds:Q28582687-F91A3924-BA97-414B-86B0-E969B963FF2B wds:Q28582687-FBD6EDE9-9D02-48DC-B673-8AD1488CCD0B
cites work	Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB Exchange of W39 by A within the N-terminal extracellular domain of the GLP-1 receptor results in a loss of receptor function Engineering of glucose-stimulated insulin secretion and biosynthesis in non-islet cells GLUT-2 gene transfer into insulinoma cells confers both low and high affinity glucose-stimulated insulin release. Relationship to glucokinase activity. Transfection of AtT-20ins cells with GLUT-2 but not GLUT-1 confers glucose-stimulated insulin secretion. Relationship to glucose metabolism Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1 Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines Metabolic coupling factors in pancreatic beta-cell signal transduction Pdx1 level defines pancreatic gene expression pattern and cell lineage differentiation Islet and stem cell transplantation for treating diabetes In vitro cultivation of human islets from expanded ductal tissue The glucagon-like peptides Signal transduction crosstalk in the endocrine system: pancreatic beta-cells and the glucose competence concept Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells. Glucagon-like peptides Glucagon-like peptide 1 stimulates insulin gene promoter activity by protein kinase A-independent activation of the rat insulin I gene cAMP response element Pancreatic beta-cells are rendered glucose-competent by the insulinotropic hormone glucagon-like peptide-1(7-37). Proglucagon processing in a rat islet cell line resembles phenotype of intestine rather than pancreas The protein kinase C inhibitors Ro 318220 and GF 109203X are equally potent inhibitors of MAPKAP kinase-1beta (Rsk-2) and p70 S6 kinase. Mutations to the third cytoplasmic domain of the glucagon-like peptide 1 (GLP-1) receptor can functionally uncouple GLP-1-stimulated insulin secretion in HIT-T15 cells Novel insulinoma cell lines produced by iterative engineering of GLUT2, glucokinase, and human insulin expression Exendin-(9-39) is an inverse agonist of the murine glucagon-like peptide-1 receptor: implications for basal intracellular cyclic adenosine 3',5'-monophosphate levels and beta-cell glucose competence Pancreas and islet transplantation for patients with diabetes Secretion and degradation of glucagon by HIT cells Overexpression of glucagon-like peptide-1 receptor in an insulin-secreting cell line enhances glucose responsiveness Proglucagon expression, posttranslational processing and secretion in SV40-transformed islet cells Constitutive receptor systems for drug discovery Glucagon-like peptide-1 (GLP-1) molecular forms in human pancreatic endocrine tumors resemble those in intestine rather than pancreas
author name string	wds:Q28582687-8B9ED05F-94C1-4997-93F0-D0C28756EBAE wds:Q28582687-8D5C1110-A92C-4787-ACB0-D518F9D9A5AA
author name string	George G. Holz Oleg G. Chepurny
rdfs:label	Over-expression of the glucagon-like peptide-1 receptor on INS-1 cells confers autocrine stimulation of insulin gene promoter activity: a strategy for production of pancreatic beta-cell lines for use in transplantation (en) Over-expression of the glucagon-like peptide-1 receptor on INS-1 cells confers autocrine stimulation of insulin gene promoter activity: a strategy for production of pancreatic beta-cell lines for use in transplantation (nl) Over-expression of the glucagon-like peptide-1 receptor on INS-1 cells confers autocrine stimulation of insulin gene promoter activity: a strategy for production of pancreatic beta-cell lines for use in transplantation (ast)
skos:prefLabel	Over-expression of the glucagon-like peptide-1 receptor on INS-1 cells confers autocrine stimulation of insulin gene promoter activity: a strategy for production of pancreatic beta-cell lines for use in transplantation (en) Over-expression of the glucagon-like peptide-1 receptor on INS-1 cells confers autocrine stimulation of insulin gene promoter activity: a strategy for production of pancreatic beta-cell lines for use in transplantation (nl) Over-expression of the glucagon-like peptide-1 receptor on INS-1 cells confers autocrine stimulation of insulin gene promoter activity: a strategy for production of pancreatic beta-cell lines for use in transplantation (ast)
name	Over-expression of the glucagon-like peptide-1 receptor on INS-1 cells confers autocrine stimulation of insulin gene promoter activity: a strategy for production of pancreatic beta-cell lines for use in transplantation (en) Over-expression of the glucagon-like peptide-1 receptor on INS-1 cells confers autocrine stimulation of insulin gene promoter activity: a strategy for production of pancreatic beta-cell lines for use in transplantation (nl) Over-expression of the glucagon-like peptide-1 receptor on INS-1 cells confers autocrine stimulation of insulin gene promoter activity: a strategy for production of pancreatic beta-cell lines for use in transplantation (ast)
title	wds:Q28582687-039B0258-9C6B-44C6-9F1F-3375D6F9DF35
title	Over-expression of the glucagon-like peptide-1 receptor on INS-1 cells confers autocrine stimulation of insulin gene promoter activity: a strategy for production of pancreatic beta-cell lines for use in transplantation (en)
page(s)	wds:Q28582687-6634B473-0CDF-4D13-AF29-3A1A27BF02D2
page(s)	191–201
instance of	wds:Q28582687-FF03D13C-7661-4994-9ECA-6F5AC17334C9
instance of	scholarly article
main subject	wds:Q28582687-8AFCEE6A-667E-49AA-92A0-A2242542359A
main subject	wd:Q7240673
PubMed ID	wds:Q28582687-9C2CCF5D-8B3E-49F4-ADD7-BA85F17EB7B7
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/11845326
PubMed ID	11845326

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