About: WAY-163909 [(7bR, 10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole], a novel 5-hydroxytryptamine 2C receptor-selective agonist with anorectic activity

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About: WAY-163909 [(7bR, 10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole], a novel 5-hydroxytryptamine 2C receptor-selective agonist with anorectic activity Goto Sponge NotDistinct Permalink

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scientific journal article

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rdf:type	Item
description	article scientifique publié en 2005 (fr) artículu científicu espublizáu en 2005 (ast) vědecký článek publikovaný v roce 2005 (cs) 2005 թվականի մայիսին հրատարակված գիտական հոդված (hy) 2005 թուականի Մայիսին հրատարակուած գիտական յօդուած (hyw) наукова стаття, опублікована в травні 2005 (uk) مقالة علمية (نشرت في مايو 2005) (ar) vedecký článok (publikovaný 2005/05/01) (sk) wetenschappelijk artikel (gepubliceerd op 2005/05/01) (nl) scientific journal article (en) im Mai 2005 veröffentlichter wissenschaftlicher Artikel (de)
publication date	wds:Q28582332-F85E8653-7180-41D9-8D32-A51E1ED8FF0F
publication date	2005-05-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28582332-D2CCA213-74A3-4F2E-8068-09CC7BEFF59B
language of work or name	English
author name string	wds:Q28582332-02CFCD9D-2CA3-4310-8602-0A90E78EBA44 wds:Q28582332-061FE2C8-2287-4456-9E34-38D58702D009 wds:Q28582332-2CAB7D2D-8A9F-469C-BD7E-38F7975FAAF1 wds:Q28582332-4257E3B5-60D1-4583-90B5-BEAC6858F4C2 wds:Q28582332-42908CAF-2741-4AA8-8736-50B151325315 wds:Q28582332-4D05356C-A211-4AE2-BD6C-CDBAEC97C399 wds:Q28582332-6D33DC17-0342-4E94-B81F-8E8CC15C756D wds:Q28582332-75E581D8-14B2-446D-B3AD-8685A1BDB85E wds:Q28582332-A1715DA2-13A2-497C-8B31-FBDED7C96777 wds:Q28582332-A1F7B9AD-576C-420F-B963-85C619B7A4E0 wds:Q28582332-CB4E44EE-6FFA-4133-8E5C-3481A396DEF1 wds:Q28582332-D5D6341F-7E38-495F-AD2F-8C503E74C58A
author name string	Jean Zhang John Dunlop Sharon Rosenzweig-Lipson Gary Stack Lee Schechter Hossein Mazandarani Annmarie L. Sabb Boyd L. Harrison Eugenia Shukhina Robert L. Vogel Sachin Kalgaonker Stacey Sukoff
rdfs:label	WAY-163909 [(7bR, 10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole], a novel 5-hydroxytryptamine 2C receptor-selective agonist with anorectic activity (en) WAY-163909 [(7bR, 10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole], a novel 5-hydroxytryptamine 2C receptor-selective agonist with anorectic activity (nl) WAY-163909 [(7bR, 10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole], a novel 5-hydroxytryptamine 2C receptor-selective agonist with anorectic activity (ast)
skos:prefLabel	WAY-163909 [(7bR, 10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole], a novel 5-hydroxytryptamine 2C receptor-selective agonist with anorectic activity (en) WAY-163909 [(7bR, 10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole], a novel 5-hydroxytryptamine 2C receptor-selective agonist with anorectic activity (nl) WAY-163909 [(7bR, 10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole], a novel 5-hydroxytryptamine 2C receptor-selective agonist with anorectic activity (ast)
name	WAY-163909 [(7bR, 10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole], a novel 5-hydroxytryptamine 2C receptor-selective agonist with anorectic activity (en) WAY-163909 [(7bR, 10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole], a novel 5-hydroxytryptamine 2C receptor-selective agonist with anorectic activity (nl) WAY-163909 [(7bR, 10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole], a novel 5-hydroxytryptamine 2C receptor-selective agonist with anorectic activity (ast)
title	wds:Q28582332-BE798F10-CD21-4FD2-A806-8FB607BED3DD
title	WAY-163909 [(7bR, 10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole], a novel 5-hydroxytryptamine 2C receptor-selective agonist with anorectic activity (en)
page(s)	wds:Q28582332-0E6F7F3A-86BC-47F9-852B-930B15993DF3
page(s)	862–869
instance of	wds:Q28582332-76FF0F1C-3D62-4B57-95DA-CB2536D4E44D
instance of	scholarly article
PubMed ID	wds:Q28582332-A7C8E13B-F8A6-4ED0-9307-3F1614851763
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/15705738
PubMed ID	15705738
published in	wds:Q28582332-A981C3B7-9AB1-4650-B95D-D05BCD829238
published in	Journal of Pharmacology and Experimental Therapeutics
issue	wds:Q28582332-CAFCC414-04B0-425D-9AF0-BD6CD0343BA9
volume	wds:Q28582332-B56656E5-DAC4-4860-842A-0B4D6BB14C07
issue	2
volume	313
DOI	wds:Q28582332-568A322D-9DFB-4C58-AB38-0BCD3BD3A485
DOI	http://dx.doi.org/10.1124/JPET.104.075382
DOI	10.1124/JPET.104.075382
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q28582332
is cites work of	Selective serotonin 5-HT(2C) receptor activation suppresses the reinforcing efficacy of cocaine and sucrose but differentially affects the incentive-salience value of cocaine- vs. sucrose-associated cues Synergism between a serotonin 5-HT2A receptor (5-HT2AR) antagonist and 5-HT2CR agonist suggests new pharmacotherapeutics for cocaine addiction Incubation of cocaine cue reactivity associates with neuroadaptations in the cortical serotonin (5-HT) 5-HT2C receptor (5-HT2CR) system Pharmacological targeting of the serotonergic system for the treatment of obesity Antidepressant-like effects of the novel, selective, 5-HT2C receptor agonist WAY-163909 in rodents S32006, a novel 5-HT2C receptor antagonist displaying broad-based antidepressant and anxiolytic properties in rodent models The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors Serotonin 5-HT2 receptor interactions with dopamine function: implications for therapeutics in cocaine use disorder The potential use of selective 5-HT2C agonists in treating obesity PSD-95 is essential for hallucinogen and atypical antipsychotic drug actions at serotonin receptors The role of serotonin in the NMDA receptor antagonist models of psychosis and cognitive impairment Innovative approaches for the development of antidepressant drugs: current and future strategies WAY-163909, a 5-HT2C agonist, enhances the preclinical potency of current antipsychotics The obesity pipeline: current strategies in the development of anti-obesity drugs 5-HT2C ligands: recent progress Pharmacological profile of the 5-HT(2C) receptor agonist WAY-163909; therapeutic potential in multiple indications Emerging drugs for obesity therapy. Investigational therapies in the treatment of obesity Serotonin2C ligands exhibiting full negative and positive intrinsic activity elicit purposeless oral movements in rats: distinct effects of agonists and inverse agonists in a rat model of Parkinson's disease Effects of the serotonin 2C receptor agonist WAY163909 on the abuse-related effects and mesolimbic dopamine neurochemistry induced by abused stimulants in rhesus monkeys. Effects of a Serotonin 2C Agonist and a 2A Antagonist on Actigraphy-Based Sleep Parameters Disrupted by Methamphetamine Self-Administration in Rhesus Monkeys. A short history of the 5-HT2C receptor: from the choroid plexus to depression, obesity and addiction treatment Imaging evaluation of 5HT2C agonists, [(11)C]WAY-163909 and [(11)C]vabicaserin, formed by Pictet-Spengler cyclization New therapeutic potential for psychoactive natural products New molecular targets in the pathophysiology of obesity and available treatment options under investigation Serotonin2C Receptors and the Motor Control of Oral Activity Multiple controls exerted by 5-HT2C receptors upon basal ganglia function: from physiology to pathophysiology 3,4-Methylenedioxymethamphetamine Increases Affiliative Behaviors in Squirrel Monkeys in a Serotonin 2A Receptor-Dependent Manner. 5-HT2C receptor modulators: a patent survey Discovery and development of 5-HT(₂C) receptor agonists for obesity: is there light at the end of the tunnel? Discriminative stimulus effects of serotonin agonists, neutral antagonists, and inverse agonists in pigeons: perspectives on intrinsic efficacy measurements in vivo Synthesis and Structure-Activity Relationships of Tool Compounds Based on WAY163909, a 5-HT2C Receptor Agonist.

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