About: Agrin regulates rapsyn interaction with surface acetylcholine receptors, and this underlies cytoskeletal anchoring and clustering

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description	artículu científicu espublizáu en 2003 (ast) vědecký článek publikovaný v roce 2003 (cs) 2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած (hyw) 2003 թվականի փետրվարին հրատարակված գիտական հոդված (hy) наукова стаття, опублікована в лютому 2003 (uk) vedecký článok (publikovaný 2003/02/28) (sk) 2003 ഫെബ്രുവരി 28 നു പ്രസിദ്ധീകരിച്ച ശാസ്ത്ര ലേഖനം (ml) مقالة علمية (نشرت في 28-2-2003) (ar) article publié dans la revue scientifique Journal of Biological Chemistry (fr) wetenschappelijk artikel (gepubliceerd op 2003/02/28) (nl) im Februar 2003 veröffentlichter wissenschaftlicher Artikel (de) scientific journal article (en)
publication date	wds:Q28565976-7809638B-37ED-4A17-889B-4268A4DCF56C
publication date	2003-02-28 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28565976-BF1E72D1-1930-4D00-9771-2264D0C0B31C
language of work or name	English
cites work	wds:Q28565976-0AD8B558-AB63-473B-A7DF-27AD9C2B69B0 wds:Q28565976-180088E6-0743-49E2-8525-3BD2717D67ED wds:Q28565976-26BEA89D-A404-4AB9-A7AF-166B16BF6DF1 wds:Q28565976-2801B1C4-DBDB-4F65-8C9D-479363B6E800 wds:Q28565976-2801B290-107D-41CA-9A52-9351AC055A37 wds:Q28565976-29D2D829-6456-4805-9DD1-9B08A2FA1927 wds:Q28565976-323FDE48-7EB1-43DF-85C0-DA28794D6670 wds:Q28565976-346D7717-D2FA-4815-8967-C94D77EA21F8 wds:Q28565976-391A41AB-6328-412F-B3B4-5854B358C7FA wds:Q28565976-4B0F5062-16DB-4DCA-AB08-AD086E8E4D5E wds:Q28565976-50357A0F-7754-4447-8A59-ED8CDA334F9F wds:Q28565976-5B750824-5066-4E34-85D3-D07A7803AB21 wds:Q28565976-5EC06F97-E1ED-4FF3-B9A5-F79F23C6645A wds:Q28565976-6CB1F8A7-54D3-4023-86B0-5CFEE5499FF8 wds:Q28565976-6D5519DB-50A2-4A3C-9067-64713014C054 wds:Q28565976-76DBE36E-60B7-4829-8B76-7EFDDD00AD63 wds:Q28565976-7CB4ECD5-CFB1-4394-9640-60BBC80C1716 wds:Q28565976-89462B27-1A6D-4FA9-9998-15CE8EC8AA7E wds:Q28565976-B6B3192C-03CE-4A51-8BB6-496B4F0E87D4 wds:Q28565976-C144181D-8388-4B9C-B77B-9823F38E287D wds:Q28565976-C3433D56-A68C-44BC-8CAC-06B738277A4A wds:Q28565976-C38F3706-CA92-4E45-83F5-61B57A5B4B84 wds:Q28565976-D645BC5B-C1F8-4024-926A-5C1CD2495B6F wds:Q28565976-DE83B8E7-0058-4895-9BA5-C7F3525C1B90 wds:Q28565976-E4F50603-229C-46E7-9556-D73CDFDC1727 wds:Q28565976-E80B5894-576D-4AE8-A185-257AB5BA2284 wds:Q28565976-F12AA0DD-94B6-4CDB-BAA8-0CBF2872B629 wds:Q28565976-F9AF3154-82FF-4FFC-AD8A-C1557D495B72 wds:Q28565976-F9AF9887-BFF8-4412-B944-05CC23D86AA3
cites work	Rapsyn mutations in humans cause endplate acetylcholine-receptor deficiency and myasthenic syndrome Rapsyn is required for MuSK signaling and recruits synaptic components to a MuSK-containing scaffold Agrin acts via a MuSK receptor complex Defective neuromuscular synaptogenesis in agrin-deficient mutant mice The agrin hypothesis Rapsyn clusters and activates the synapse-specific receptor tyrosine kinase MuSK. Failure of postsynaptic specialization to develop at neuromuscular junctions of rapsyn-deficient mice. Induction, assembly, maturation and maintenance of a postsynaptic apparatus Acetylcholine receptors are required for agrin-induced clustering of postsynaptic proteins. Association of muscle-specific kinase MuSK with the acetylcholine receptor in mammalian muscle. Agrin-induced acetylcholine receptor clustering in mammalian muscle requires tyrosine phosphorylation Laminin-1 redistributes postsynaptic proteins and requires rapsyn, tyrosine phosphorylation, and Src and Fyn to stably cluster acetylcholine receptors Agrin-induced phosphorylation of the acetylcholine receptor regulates cytoskeletal anchoring and clustering Agrin-induced activation of acetylcholine receptor-bound Src family kinases requires Rapsyn and correlates with acetylcholine receptor clustering. The postsynaptic 43k protein clusters muscle nicotinic acetylcholine receptors in xenopus oocytes Rapsyn may function as a link between the acetylcholine receptor and the agrin-binding dystrophin-associated glycoprotein complex Increased expression of the 43-kD protein disrupts acetylcholine receptor clustering in myotubes wd:Q56690173 Rapid formation and remodeling of postsynaptic densities in developing dendrites. Distinct roles of nerve and muscle in postsynaptic differentiation of the neuromuscular synapse Patterning of muscle acetylcholine receptor gene expression in the absence of motor innervation Laminin-induced acetylcholine receptor clustering: an alternative pathway The relationship of the postsynaptic 43K protein to acetylcholine receptors in receptor clusters isolated from cultured rat myotubes Postsynaptic clustering of major GABAA receptor subtypes requires the gamma 2 subunit and gephyrin. Differential targeting of components of the dystrophin complex to the postsynaptic membrane Ion channel of acetylcholine receptor reconstructed from images of postsynaptic membranes Three-dimensional structure of the nicotinic acetylcholine receptor and location of the major associated 43-kD cytoskeletal protein, determined at 22 A by low dose electron microscopy and x-ray diffraction to 12.5 A. Real-time detection of the surface delivery of newly synthesized membrane proteins Mechanism of agrin-induced acetylcholine receptor aggregation
author name string	wds:Q28565976-06FA6BF0-CAAD-4956-A52F-975677CEC4E4 wds:Q28565976-0F2F463C-1E8C-4BB6-8848-C4F03AF88617 wds:Q28565976-6974A020-9393-4D5B-BBA2-E6B9AE098888 wds:Q28565976-9053542E-1E1A-453F-8ECD-CFD0CD110881 wds:Q28565976-E5A510FD-ECB2-4492-B948-3CFA388103B5 wds:Q28565976-F141DE25-B918-44F0-89DD-457E4EB7DE1A wds:Q28565976-F62E83EF-9E99-4EB3-81C2-730AFFE0BBF7
author name string	Christian Fuhrer Raffaella Willmann Hans Rudolf Brenner Lucia S. Borges Martijn Moransard Michael J. Ferns P. Angelo Marangi
rdfs:label	Agrin regulates rapsyn interaction with surface acetylcholine receptors, and this underlies cytoskeletal anchoring and clustering (en) Agrin regulates rapsyn interaction with surface acetylcholine receptors, and this underlies cytoskeletal anchoring and clustering (nl) Agrin regulates rapsyn interaction with surface acetylcholine receptors, and this underlies cytoskeletal anchoring and clustering (ast)
skos:prefLabel	Agrin regulates rapsyn interaction with surface acetylcholine receptors, and this underlies cytoskeletal anchoring and clustering (en) Agrin regulates rapsyn interaction with surface acetylcholine receptors, and this underlies cytoskeletal anchoring and clustering (nl) Agrin regulates rapsyn interaction with surface acetylcholine receptors, and this underlies cytoskeletal anchoring and clustering (ast)
name	Agrin regulates rapsyn interaction with surface acetylcholine receptors, and this underlies cytoskeletal anchoring and clustering (en) Agrin regulates rapsyn interaction with surface acetylcholine receptors, and this underlies cytoskeletal anchoring and clustering (nl) Agrin regulates rapsyn interaction with surface acetylcholine receptors, and this underlies cytoskeletal anchoring and clustering (ast)
title	wds:Q28565976-FAC133B2-100D-4DA4-B617-A37BBEC0F5E9
title	Agrin regulates rapsyn interaction with surface acetylcholine receptors, and this underlies cytoskeletal anchoring and clustering (en)

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