About: Src kinase activity is essential for osteoclast function

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rdf:type	Item
description	artículu científicu espublizáu en 2004 (ast) vědecký článek publikovaný v roce 2004 (cs) 2004 թվականի ապրիլին հրատարակված գիտական հոդված (hy) 2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած (hyw) наукова стаття, опублікована у квітні 2004 (uk) vedecký článok (publikovaný 2004/04/23) (sk) wetenschappelijk artikel (gepubliceerd op 2004/04/23) (nl) مقالة علمية (نشرت في 23-4-2004) (ar) article publié dans la revue scientifique Journal of Biological Chemistry (fr) im April 2004 veröffentlichter wissenschaftlicher Artikel (de) scientific journal article (en)
publication date	wds:Q28513236-AF8569C7-5B7E-4D66-947E-591110D6DD62
publication date	2004-04-23 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28513236-55B87500-37BF-4356-9261-A5CAE2CEB104
language of work or name	English
cites work	wds:Q28513236-97473D75-BA64-4AC2-8D4B-C2696E233863
cites work	Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
author name string	wds:Q28513236-0CB22097-2FD9-47CB-B973-5306C9FF5019 wds:Q28513236-646333E3-EBFE-4C39-AB84-9F43054A3E2E wds:Q28513236-7042C6FB-74A0-425C-BADC-4F98CDD1374A wds:Q28513236-CA428A2A-9AFC-4B9B-9922-5F64E09A257B wds:Q28513236-E4CDFEA0-744D-4EA3-B54C-1BDF4625CB4C wds:Q28513236-ED8ACBDB-CCBA-4CEF-BC13-95C11A2540FE
OpenCitations bibliographic resource ID	wds:Q28513236-131AFBCB-EFCA-49BE-A772-0B779149EC02
OpenCitations bibliographic resource ID	https://w3id.org/oc/corpus/br/1342452
author name string	Sakae Tanaka Roland Baron Tsuyoshi Miyazaki Archana Sanjay Lynn Neff William C. Horne
OpenCitations bibliographic resource ID	1342452
rdfs:label	Src kinase activity is essential for osteoclast function (en) Src kinase activity is essential for osteoclast function (nl) Src kinase activity is essential for osteoclast function (ast)
skos:prefLabel	Src kinase activity is essential for osteoclast function (en) Src kinase activity is essential for osteoclast function (nl) Src kinase activity is essential for osteoclast function (ast)
name	Src kinase activity is essential for osteoclast function (en) Src kinase activity is essential for osteoclast function (nl) Src kinase activity is essential for osteoclast function (ast)
title	wds:Q28513236-1811ACCF-C2BE-4F0E-BED6-CAE4C488EA36
title	Src kinase activity is essential for osteoclast function (en)
page(s)	wds:Q28513236-86E14742-FD14-4A47-B20A-78D50B21EDD6
page(s)	17660–17666
instance of	wds:Q28513236-2C27AA7A-111D-4E8D-9381-ABBA2ACDCC10
instance of	scholarly article
main subject	wds:Q28513236-764481B3-1832-4AF0-8B93-D1F332EFDA82 wds:Q28513236-BFEFE6AC-25E8-4F8C-A5CB-2A5B7475720F
main subject	Rous sarcoma oncogene PTK2 protein tyrosine kinase 2 beta
PubMed ID	wds:Q28513236-13BF4A41-C394-4421-A781-7E4532DB3005
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/14739300
PubMed ID	14739300
published in	wds:Q28513236-8E628C03-F28F-4CE2-A088-9BB110730235
published in	Journal of Biological Chemistry
issue	wds:Q28513236-4987B3CD-A766-4719-9E2A-257D30DC9230
volume	wds:Q28513236-25E1311A-853E-4B47-BA47-134214922839
issue	17
volume	279
DOI	wds:Q28513236-D1FC2AE8-02CA-4691-98F8-2E16919331B7
DOI	http://dx.doi.org/10.1074/JBC.M311032200
DOI	10.1074/JBC.M311032200
Fatcat ID	wds:Q28513236-49FBB9D1-BBF7-47C2-BC64-4B3A0F228A6A
Fatcat ID	release_t5z3ozrcqrgozhnpurzcggm5jy
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q28513236
is cites work of	Apatite-mediated actin dynamics in resorbing osteoclasts The loss of Cbl-phosphatidylinositol 3-kinase interaction perturbs RANKL-mediated signaling, inhibiting bone resorption and promoting osteoclast survival Loss of protein kinase C-δ protects against LPS-induced osteolysis owing to an intrinsic defect in osteoclastic bone resorption Ablation of the Sam68 RNA binding protein protects mice from age-related bone loss Interaction among cells of bone, immune system, and solid tumors leads to bone metastases Inositol polyphosphate 4-phosphatase B as a regulator of bone mass in mice and humans Calpain is required for normal osteoclast function and is down-regulated by calcitonin Zfp521 antagonizes Runx2, delays osteoblast differentiation in vitro, and promotes bone formation in vivo The localization of FGFR3 mutations causing thanatophoric dysplasia type I differentially affects phosphorylation, processing and ubiquitylation of the receptor Identification and functional characterization of an Src homology domain 3 domain-binding site on Cbl Skeletal remodeling in health and disease c-Src control of chloride channel support for osteoclast HCl transport and bone resorption Dynamin forms a Src kinase-sensitive complex with Cbl and regulates podosomes and osteoclast activity The tyrosine kinase activity of c-Src regulates actin dynamics and organization of podosomes in osteoclasts Src-dependent repression of ARF6 is required to maintain podosome-rich sealing zones in bone-digesting osteoclasts Microtubule dynamic instability controls podosome patterning in osteoclasts through EB1, cortactin, and Src. Dasatinib combined with docetaxel for castration-resistant prostate cancer: results from a phase 1-2 study Dishevelled-2 docks and activates Src in a Wnt-dependent manner Cbl-mediated degradation of Lyn and Fyn induced by constitutive fibroblast growth factor receptor-2 activation supports osteoblast differentiation 3BP2 adapter protein is required for receptor activator of NFκB ligand (RANKL)-induced osteoclast differentiation of RAW264.7 cells Physical and functional association of c-Src and adhesion and degranulation promoting adaptor protein (ADAP) in osteoclastogenesis in vitro Evidence that the kinase-truncated c-Src regulates NF-κB signaling by targeting NEMO. Inhibition of the classical NF-kappaB pathway prevents osteoclast bone-resorbing activity. Signaling networks regulating leukocyte podosome dynamics and function Docetaxel and dasatinib or placebo in men with metastatic castration-resistant prostate cancer (READY): a randomised, double-blind phase 3 trial TULA-2, a novel histidine phosphatase, regulates bone remodeling by modulating osteoclast function Osteoclasts: what do they do and how do they do it? Phase I study of dasatinib (BMS-354825) in Japanese patients with solid tumors. Treatment options in castration-resistant prostate cancer: current therapies and emerging docetaxel-based regimens Inhibition of Hsp90 activates osteoclast c-Src signaling and promotes growth of prostate carcinoma cells in bone Proline-rich tyrosine kinase 2 regulates osteoprogenitor cells and bone formation, and offers an anabolic treatment approach for osteoporosis Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2(-/-) mice Dual focal adhesion kinase/Pyk2 inhibitor has positive effects on bone tumors: implications for bone metastases

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