About: Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4

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rdf:type	Item
description	artículu científicu espublizáu en 1991 (ast) vědecký článek publikovaný v roce 1991 (cs) 1991 թվականի սեպտեմբերին հրատարակված գիտական հոդված (hy) наукова стаття, опублікована у вересні 1991 (uk) 1991 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած (hyw) vedecký článok (publikovaný 1991/09/12) (sk) مقالة علمية (نشرت في 12-9-1991) (ar) научни чланак (објављен 1991/09/12) (sr) article publié dans la revue scientifique Nature (fr) scientific journal article (en) im September 1991 veröffentlichter wissenschaftlicher Artikel (de) wetenschappelijk artikel (gepubliceerd op 1991/09/12) (nl)
publication date	wds:Q28511808-AA64C789-5C54-4166-A5F2-003410DBF8A6
publication date	1991-09-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28511808-D5B59943-61D1-4F0C-AFA0-FF0575CBF438
language of work or name	English
cites work	wds:Q28511808-1764F85F-BAA0-4373-B1F2-8721BBC298D7 wds:Q28511808-185824CC-22C6-4428-8F58-2489E053CF20 wds:Q28511808-1A1ADD22-4D2E-4460-ADF8-27F9D5CF9409 wds:Q28511808-1C21A432-9853-4364-A338-13D2454D1295 wds:Q28511808-1DB247A2-BB01-407F-872C-ECF6BA328420 wds:Q28511808-2159AC61-5F4A-4DA9-855E-94717B2F80F7 wds:Q28511808-31175737-CADC-43A5-94CF-5AC0DE14F7F0 wds:Q28511808-352318C5-0B63-4240-AEA0-5CCDAA521CAF wds:Q28511808-4069A060-6368-4758-889A-79E166B6EA76 wds:Q28511808-52D147AE-977A-4BB8-BDBF-22C3102E2F65 wds:Q28511808-60D5555E-20CD-490E-9E77-F2E5C1068E90 wds:Q28511808-65027A99-DDED-4767-9BF4-A40CA1331DFE wds:Q28511808-658077A1-8505-4105-8771-173F319E5007 wds:Q28511808-6625151F-6ECF-4D65-8A60-D07C1AC557B5 wds:Q28511808-693F73E7-6B2B-4A39-AAD2-110825DC7A1D wds:Q28511808-72199DB5-4C02-4DE6-A3EE-C4E406045C2D wds:Q28511808-76A793A8-3E6C-4CD1-9C1D-AF6453B93F58 wds:Q28511808-7AA45AF5-8E08-4757-A3F6-AFAA724EC870 wds:Q28511808-844ED667-D637-4FDF-9DAF-C30F00B97C6A wds:Q28511808-84CFBFA4-2B9F-4E80-9430-20615D1ABCCD wds:Q28511808-8BB9EA0F-7F80-4086-B387-1BB33E7A2491 wds:Q28511808-8C2B7CEC-FAA0-40FA-B130-B29323D5DCFD wds:Q28511808-9FE793B3-46BD-4AA4-8A9C-130DC14433D8 wds:Q28511808-A0F301BD-9F22-451A-B554-89EA68AAD640 wds:Q28511808-B1B2E2AD-28DE-4B7A-9F83-7A9075F86DDE wds:Q28511808-B9308A5D-D614-4E7A-9B85-69C463A49A82 wds:Q28511808-C12A5695-8603-42DC-89F3-C4BE6130F748 wds:Q28511808-CA545CE0-E7D4-4546-915B-410506B8E55A wds:Q28511808-D65FA51A-7F05-4578-9502-120C4DDA1674 wds:Q28511808-DF6E1E03-E046-4E35-B7D3-5BA104512F3F wds:Q28511808-EC452959-9056-46D6-B0AD-BB43C0C1E6B6 wds:Q28511808-EF45C5A4-7210-446B-876D-7BD3BBD50539
cites work	Therapy with monoclonal antibodies by elimination of T-cell subsets in vivo Induction of cytotoxic T-cell responses in vivo in the absence of CD4 helper cells T-lymphocyte recognition of antigen in association with gene products of the major histocompatibility complex Isolation of cDNA clones encoding T cell-specific membrane-associated proteins A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vector Molecular biology and function of CD4 and CD8 Cell surface antigen expression on thymocytes: development and phenotypic differentiation of intrathymic subsets T cell development in the adult murine thymus: changes in the expression of the surface antigens Ly2, L3T4 and B2A2 during development from early precursor cells to emigrants Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes T cell tolerance by clonal elimination in the thymus CD8 is needed for development of cytotoxic T cells but not helper T cells Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells Establishment in culture of pluripotential cells from mouse embryos T4+ T helper cell function in vivo: differential requirement for induction of antiviral cytotoxic T-cell and antibody responses Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells Transgenesis by means of blastocyst-derived embryonic stem cell lines Different roles for L3T4+ and Lyt 2+ T cell subsets in the control of an acute herpes simplex virus infection of the skin and nervous system Production of a mutation in mouse En-2 gene by homologous recombination in embryonic stem cells. Insertion of DNA sequences into the human chromosomal beta-globin locus by homologous recombination Functional subclasses of T-lymphocytes bearing different Ly antigens. I. The generation of functionally distinct T-cell subclasses is a differentiative process independent of antigen Developmental status and reconstitution potential of subpopulations of murine thymocytes Impaired generation of anti-viral cytotoxicity against lymphocytic choriomeningitis and vaccinia virus in mice treated with CD4-specific monoclonal antibody The lymphoreticular system in triggering virus plus self-specific cytotoxic T cells: evidence for T help Quantitative representation of all T cells committed to develop into cytotoxic effector cells and/or interleukin 2 activity-producing helper cells within murine T lymphocyte subsets CD4 expressed on earliest T-lineage precursor cells in the adult murine thymus L3T4 antigen expression by hemopoietic precursor cells Cooperation between cytotoxic and helper T lymphocytes in protection against lethal Sendai virus infection. Protection by T cells is MHC-restricted and MHC-regulated; a model for MHC-disease associations A T helper cell for anti-viral cytotoxic T-cell responses Different rules govern help for cytotoxic T cells and B cells SKIN ALLOGRAFT REJECTION BY L3/t4+ AND LYT-2+ T CELL SUBESTS
author name string	wds:Q28511808-3229A86D-FDA0-4AA0-83CD-F3C99584D9FC wds:Q28511808-48EBAB1A-D2D5-4F05-B0FB-1A107455A51C wds:Q28511808-571DAC24-0815-472D-A1F0-98A1B968561A wds:Q28511808-618A3670-827B-487D-9552-EF5012FD05DA wds:Q28511808-8BC4E2B3-1AED-4028-991F-4850CFD1FE2E wds:Q28511808-99D29CAC-64C7-41BD-8E25-9D93BEC67E6B wds:Q28511808-BE22F1C0-86EC-4C42-92F8-68912BE484BF wds:Q28511808-C99681EE-E685-460C-8F16-FD4177254ECB
author name string	Paige CJ Rahemtulla A Kündig TM Schilham MW Narendran A Wakeham A Sambhara SR Arabian A
rdfs:label	Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4 (en) Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4 (nl) Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4 (ast)

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