About: Inactivation of the Friedreich ataxia mouse gene leads to early embryonic lethality without iron accumulation

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Inactivation of the Friedreich ataxia mouse gene leads to early embryonic lethality without iron accumulation Goto Sponge NotDistinct Permalink

An Entity of Type : wikibase:Item, within Data Space : wikidata.demo.openlinksw.com associated with source document(s)

scientific journal article

Attributes	Values
rdf:type	Item
description	artículu científicu espublizáu en 2000 (ast) vědecký článek publikovaný v roce 2000 (cs) 2000 թուականի Մայիսին հրատարակուած գիտական յօդուած (hyw) наукова стаття, опублікована в травні 2000 (uk) 2000 թվականի մայիսին հրատարակված գիտական հոդված (hy) vedecký článok (publikovaný 2000/05/01) (sk) مقالة علمية (نشرت في مايو 2000) (ar) wetenschappelijk artikel (gepubliceerd op 2000/05/01) (nl) scientific journal article (en) im Mai 2000 veröffentlichter wissenschaftlicher Artikel (de)
publication date	wds:Q28510128-4F4459DD-7092-458B-9577-3ACBA2D31B5E
publication date	2000-05-01 00:00:00Z (xsd:dateTime)
author name string	wds:Q28510128-1275E055-0987-4F44-B5EA-7299901B4841 wds:Q28510128-15BD3D38-C3D4-4A87-AEB2-64C4D5B90DD8 wds:Q28510128-404BB632-B1B9-42BB-A141-1952C0907CBF wds:Q28510128-424985F8-2749-41B4-836C-CEBC26CBB2FB wds:Q28510128-43108DCF-CFD5-4036-AFDC-A2B14C7BDD79 wds:Q28510128-77147392-1413-4C11-BFD1-120B90CF6656 wds:Q28510128-A3126B8E-DD5B-45FE-8C2B-B0B49B1FF30A wds:Q28510128-C0E0EB0D-5F71-4314-8963-343D804829EA
OpenCitations bibliographic resource ID	wds:Q28510128-BFBA6A21-BD1A-4E91-94FB-6BEAF3214F29
OpenCitations bibliographic resource ID	https://w3id.org/oc/corpus/br/2140902
author name string	M Koenig A Gansmuller A Dierich M LeMeur M Cossée P Dollé H Koutnikova K Fischbeck
OpenCitations bibliographic resource ID	2140902
rdfs:label	Inactivation of the Friedreich ataxia mouse gene leads to early embryonic lethality without iron accumulation (en) Inactivation of the Friedreich ataxia mouse gene leads to early embryonic lethality without iron accumulation (nl) Inactivation of the Friedreich ataxia mouse gene leads to early embryonic lethality without iron accumulation (ast)
skos:prefLabel	Inactivation of the Friedreich ataxia mouse gene leads to early embryonic lethality without iron accumulation (en) Inactivation of the Friedreich ataxia mouse gene leads to early embryonic lethality without iron accumulation (nl) Inactivation of the Friedreich ataxia mouse gene leads to early embryonic lethality without iron accumulation (ast)
name	Inactivation of the Friedreich ataxia mouse gene leads to early embryonic lethality without iron accumulation (en) Inactivation of the Friedreich ataxia mouse gene leads to early embryonic lethality without iron accumulation (nl) Inactivation of the Friedreich ataxia mouse gene leads to early embryonic lethality without iron accumulation (ast)
author	wds:Q28510128-FCF84F15-680D-446E-BD45-8F36389463FC
author	Helene Puccio
title	wds:Q28510128-687AFC89-37E6-4084-AF5A-4CB03A804B84
title	Inactivation of the Friedreich ataxia mouse gene leads to early embryonic lethality without iron accumulation (en)
page(s)	wds:Q28510128-4BFF44C2-BC58-44CA-843E-84A201757FDE
page(s)	1219-1226
instance of	wds:Q28510128-267DA82B-830A-4A8E-83C6-170ED21C23BC
instance of	scholarly article
main subject	wds:Q28510128-03721C4F-4B62-45F2-A49A-BAE7E56D86F2 wds:Q28510128-1B1DC328-F3E3-45CE-A4C5-01E56038313D wds:Q28510128-965911F5-64A4-49F5-880E-9ACFA165450F
main subject	Friedreich ataxia iron Frataxin
PubMed ID	wds:Q28510128-8C76569E-5E52-4FBB-B897-5849E00B3AC6
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/10767347
PubMed ID	10767347
published in	wds:Q28510128-6FE7DC45-C762-4736-A234-E195A88C77A6
published in	Human Molecular Genetics
issue	wds:Q28510128-F22E8112-D450-4BF7-8A91-88DD529EAAA2
volume	wds:Q28510128-D3E25407-AD01-4FB0-AB81-630A43346CD6
issue	8
volume	9
DOI	wds:Q28510128-49181643-BFA5-4AF0-BC92-05FE2C4199C6
DOI	http://dx.doi.org/10.1093/HMG/9.8.1219
DOI	10.1093/HMG/9.8.1219
ResearchGate publication ID	wds:Q28510128-B3B3929D-7262-4679-831D-1A90A62A775C
ResearchGate publication ID	12549896
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q28510128
is cites work of	Therapeutic developments in Friedreich ataxia Friedreich ataxia: molecular mechanisms, redox considerations, and therapeutic opportunities Friedreich ataxia-update on pathogenesis and possible therapies A TAT-frataxin fusion protein increases lifespan and cardiac function in a conditional Friedreich's ataxia mouse model Frataxin deficiency leads to defects in expression of antioxidants and Nrf2 expression in dorsal root ganglia of the Friedreich's ataxia YG8R mouse model Iron-sulfur protein maturation in human cells: evidence for a function of frataxin Mitochondrial iron-sulfur cluster dysfunction in neurodegenerative disease Dysregulation of cellular iron metabolism in Friedreich ataxia: from primary iron-sulfur cluster deficit to mitochondrial iron accumulation. Mouse models for Friedreich ataxia exhibit cardiomyopathy, sensory nerve defect and Fe-S enzyme deficiency followed by intramitochondrial iron deposits Friedreich ataxia mouse models with progressive cerebellar and sensory ataxia reveal autophagic neurodegeneration in dorsal root ganglia Autosomal recessive cerebellar ataxias Friedreich ataxia: a paradigm for mitochondrial diseases HDAC inhibitors correct frataxin deficiency in a Friedreich ataxia mouse model Neurodegenerative disorders associated with diabetes mellitus Idebenone and reduced cardiac hypertrophy in Friedreich's ataxia Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol The genetics of essential metal homeostasis during development The role of mitochondrial DNA copy number in mammalian fertility. Friedreich ataxia: from GAA triplet-repeat expansion to frataxin deficiency Biogenesis of iron-sulfur proteins in eukaryotes: components, mechanism and pathology Effector role reversal during evolution: the case of frataxin in Fe-S cluster biosynthesis Iron homeostasis: insights from genetics and animal models In vivo maturation of human frataxin Crystal structure of human frataxin Understanding the binding properties of an unusual metal-binding protein--a study of bacterial frataxin The Friedreich's ataxia protein frataxin modulates DNA base excision repair in prokaryotes and mammals Pathways to motor incoordination: the inherited ataxias Frataxin activates mitochondrial energy conversion and oxidative phosphorylation PGC-1alpha down-regulation affects the antioxidant response in Friedreich's ataxia GAA repeat expansion mutation mouse models of Friedreich ataxia exhibit oxidative stress leading to progressive neuronal and cardiac pathology

Faceted Search & Find service v1.16.117 as of May 05 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3239 as of May 5 2024, on Linux (x86_64-centos_6-linux-gnu), Single-Server Edition (378 GB total memory, 196 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software