About: Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity

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rdf:type	Item
description	artículu científicu espublizáu en 2007 (ast) vědecký článek publikovaný v roce 2007 (cs) مقالة علمية (نشرت في أغسطس 2007) (ar) наукова стаття, опублікована в серпні 2007 (uk) 2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած (hyw) 2007 թվականի օգոստոսին հրատարակված գիտական հոդված (hy) vedecký článok (publikovaný 2007/08/01) (sk) wetenschappelijk artikel (gepubliceerd op 2007/08/01) (nl) article scientifique publié en 2007 (fr) scientific journal article (en) im August 2007 veröffentlichter wissenschaftlicher Artikel (de)
publication date	wds:Q28509565-ED6A98AB-B6B2-4D43-965A-3B809CA8667D
publication date	2007-06-02 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28509565-E5D0831E-4DE0-4737-9EF2-652E481CD7DF
language of work or name	English
author name string	wds:Q28509565-1F8E6F11-6B24-4889-8D30-B730C9F4E3D0 wds:Q28509565-39152F49-0C8A-40D7-B4E4-1DB9D0F33B66 wds:Q28509565-412233F6-348D-48C0-9638-9B7BE7D32CA1 wds:Q28509565-45BE2D39-B3FC-4176-A774-12A8E0363B5E wds:Q28509565-47E4CF0F-8CA0-46E1-A674-29FDD1BC8716 wds:Q28509565-8243B832-9C36-4CF9-B40E-D3A3A1640F8B wds:Q28509565-88260049-8A9C-42A1-BA8C-5F013B512EFC wds:Q28509565-89590D02-7BD7-4AE1-A305-510189A449CF wds:Q28509565-ACDF6BE7-3464-457B-A01E-75C3ACEB0954
OpenCitations bibliographic resource ID	wds:Q28509565-541D9E4A-D058-482A-813D-12F07AEBEDA7
OpenCitations bibliographic resource ID	https://w3id.org/oc/corpus/br/3728480
author name string	Peng Li Juan P Palazzo Alessandro Bombonati Stephanie Schulz Linda D Siracusa Giovanni M Pitari Yihuan Xu Terry M Hyslop Amy A Baran
OpenCitations bibliographic resource ID	3728480
rdfs:label	Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity (en) Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity (nl) Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity (ast)
skos:prefLabel	Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity (en) Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity (nl) Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity (ast)
name	Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity (en) Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity (nl) Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity (ast)
author	wds:Q28509565-CB49C764-8C45-4C86-9682-F34316119A3A
author	Scott A. Waldman
title	wds:Q28509565-8AC1B87F-348D-4752-AD64-8AE59D7DF4A0
title	Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity (en)
page(s)	wds:Q28509565-3B5D7F34-243F-45CB-8357-A422A95DD278
page(s)	599-607
instance of	wds:Q28509565-D6DD64EF-B4EE-42DC-8C9C-40613831376D
instance of	scholarly article
main subject	wds:Q28509565-4A65B30C-EF26-41CB-BCC9-C9F4ED28FE54 wds:Q28509565-DDA83C0F-82AE-44CE-B28E-93B81DB8E461
main subject	Adenomatous polyposis coli protein Guanylate cyclase 2c
PubMed ID	wds:Q28509565-C70BC930-38F9-44C8-816B-1E6B2868DBE7
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/17681179
PubMed ID	17681179
published in	wds:Q28509565-74B4653C-1724-464C-8116-ECB0656AA0F0
published in	Gastroenterology
issue	wds:Q28509565-C7C176FB-A43B-4727-ACCB-B8AC75199D8B
volume	wds:Q28509565-E0E229AC-A248-4E0C-9979-D4820DF4FEBF
issue	2
volume	133
DOI	wds:Q28509565-AED05CF9-BE78-4021-8005-0763485FC8FF
DOI	http://dx.doi.org/10.1053/J.GASTRO.2007.05.052
DOI	10.1053/J.GASTRO.2007.05.052
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q28509565
is cites work of	GUCY2C opposes systemic genotoxic tumorigenesis by regulating AKT-dependent intestinal barrier integrity Loss of guanylyl cyclase C (GCC) signaling leads to dysfunctional intestinal barrier The paracrine hormone for the GUCY2C tumor suppressor, guanylin, is universally lost in colorectal cancer The guanylate cyclase-C signaling pathway is down-regulated in inflammatory bowel disease Activation of guanylate cyclase C signaling pathway protects intestinal epithelial cells from acute radiation-induced apoptosis. Guanylin and uroguanylin are produced by mouse intestinal epithelial cells of columnar and secretory lineage Guanylate cyclase C as a target for prevention, detection, and therapy in colorectal cancer Obesity-Induced Colorectal Cancer Is Driven by Caloric Silencing of the Guanylin-GUCY2C Paracrine Signaling Axis A uroguanylin-GUCY2C endocrine axis regulates feeding in mice Molecular Physiology of Membrane Guanylyl Cyclase Receptors The pro-apoptotic K-Ras 4A proto-oncoprotein does not affect tumorigenesis in the ApcMin/+ mouse small intestine. The uroguanylin system and human disease Bacterial heat-stable enterotoxins: translation of pathogenic peptides into novel targeted diagnostics and therapeutics Homeostatic control of the crypt-villus axis by the bacterial enterotoxin receptor guanylyl cyclase C restricts the proliferating compartment in intestine. Association of GUCY2C expression in lymph nodes with time to recurrence and disease-free survival in pN0 colorectal cancer Can colorectal cancer be prevented or treated by oral hormone replacement therapy? Colorectal cancer is a paracrine deficiency syndrome amenable to oral hormone replacement therapy Guanylyl cyclase C-induced immunotherapeutic responses opposing tumor metastases without autoimmunity Occult tumor burden contributes to racial disparities in stage-specific colorectal cancer outcomes. Bile acids initiate lineage-addicted gastroesophageal tumorigenesis by suppressing the EGF receptor-AKT axis Does obesity promote the development of colorectal cancer? The role of cyclic nucleotide signaling pathways in cancer: targets for prevention and treatment Guanylyl cyclase C in colorectal cancer: susceptibility gene and potential therapeutic target Lineage-specific T-cell responses to cancer mucosa antigen oppose systemic metastases without mucosal inflammatory disease The hormone receptor GUCY2C suppresses intestinal tumor formation by inhibiting AKT signaling. Guanylyl cyclase C prevents colon cancer metastasis by regulating tumor epithelial cell matrix metalloproteinase-9 Intestinal cell proliferation and senescence are regulated by receptor guanylyl cyclase C and p21. Antiobesity pharmacotherapy: new drugs and emerging targets Occult tumor burden predicts disease recurrence in lymph node-negative colorectal cancer

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