About: Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting

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description	artículu científicu espublizáu en 2004 (ast) vědecký článek publikovaný v roce 2004 (cs) 2004 թվականի հունիսին հրատարակված գիտական հոդված (hy) наукова стаття, опублікована в червні 2004 (uk) 2004 թուականի Յունիսին հրատարակուած գիտական յօդուած (hyw) article publié dans la revue scientifique Nature (fr) vedecký článok (publikovaný 2004/06/24) (sk) مقالة علمية (نشرت في 24-6-2004) (ar) scientific journal article (en) wetenschappelijk artikel (gepubliceerd op 2004/06/24) (nl) im Juni 2004 veröffentlichter wissenschaftlicher Artikel (de)
publication date	wds:Q28508038-FD92C396-4C19-4900-82B1-055C9FD1CBA3
publication date	2004-06-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28508038-14D7ECF5-3960-4C8A-8CC8-FDEAC64ACC97
language of work or name	English
cites work	wds:Q28508038-11C3280A-CF82-492D-977A-80C27D091376 wds:Q28508038-1CCDCD0A-F8BB-4176-AE23-F327C78A39C3 wds:Q28508038-210BDF70-A977-4A56-9D0B-C3CB8794BE7D wds:Q28508038-243B76E3-8220-41C0-ACDB-FFC5224E7A54 wds:Q28508038-2C7DB952-D18D-47D6-AC85-43862621A044 wds:Q28508038-371C7CA4-7EE1-4B1F-B9FE-CB64CA418A71 wds:Q28508038-40FD5DC2-4B48-45E9-B2E3-F75079BA30A0 wds:Q28508038-45DE8CE8-16C0-4901-87F2-6F158B17F79C wds:Q28508038-583C03EB-AA45-44C3-ACF8-7642EBE0EEED wds:Q28508038-60A3C8B2-4A20-4ACB-A767-BE5D10D2B467 wds:Q28508038-9223C7DC-1668-4E3B-A7CE-3A2EF97EF42C wds:Q28508038-ACEACFFD-6315-47C6-9EB9-EB69E2BD0287 wds:Q28508038-B4B9C7D5-8199-46DA-B717-FEAE4266843A wds:Q28508038-B595361D-D347-4C2C-B02F-F122386B5983 wds:Q28508038-C4A77901-0D1A-4DE5-9935-60D147B877C0 wds:Q28508038-C6B93A0D-FD1B-4D1B-B2EF-9121F63A325B wds:Q28508038-CCEE36F7-CBFE-494F-8AD6-ADCBAF1C7E65 wds:Q28508038-D7221113-564D-402D-9034-F4CF9466F513 wds:Q28508038-D9A7ADD2-9E7C-49ED-B433-7030A792134A wds:Q28508038-E0EB54C1-17FF-4986-A24D-5F7AA4BFD426 wds:Q28508038-E7C4D43C-34DA-47A8-A6CA-A66B54D26E1A wds:Q28508038-E8634124-DDFC-4D2B-A2B3-1C34A5AF6F56 wds:Q28508038-FE44877E-22A8-4D81-98EF-AE8063642DDA
cites work	Paternal imprints can be established on the maternal Igf2-H19 locus without altering replication timing of DNA. De novo DNA methylation is dispensable for the initiation and propagation of X chromosome inactivation. Genomic imprinting: parental influence on the genome Targeted mutation of the DNA methyltransferase gene results in embryonic lethality The H19 methylation imprint is erased and re-established differentially on the parental alleles during male germ cell development. Gene-specific timing and epigenetic memory in oocyte imprinting. The paternal methylation imprint of the mouse H19 locus is acquired in the gonocyte stage during foetal testis development. A novel Dnmt3a isoform produced from an alternative promoter localizes to euchromatin and its expression correlates with active de novo methylation The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a Dnmt3L and the establishment of maternal genomic imprints. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development High sensitivity mapping of methylated cytosines Imprinting and the epigenetic asymmetry between parental genomes. Somatic mutations in the neurofibromatosis 1 gene in human tumors Direct removal in the mouse of a floxed neo gene from a three-loxP conditional knockout allele by two novel approaches Germ cell deficiency causes testis cord differentiation in reconstituted mouse fetal ovaries A global disorder of imprinting in the human female germ line. Targeted insertion of Cre recombinase into the TNAP gene: excision in primordial germ cells Epigenetic modifications necessary for normal development are established during oocyte growth in mice. The maternally transcribed gene p57KIP2 (CDNK1C) is abnormally expressed in both androgenetic and biparental complete hydatidiform moles Maternal primary imprinting is established at a specific time for each gene throughout oocyte growth Maternal alleles acquiring paternal methylation patterns in biparental complete hydatidiform moles. Lack of involvement of known DNA methyltransferases in familial hydatidiform mole implies the involvement of other factors in establishment of imprinting in the human female germline
author name string	wds:Q28508038-2389AF46-07AA-44F1-B79C-6F70DD8453F6 wds:Q28508038-57E2A445-B90B-4AAF-9AB6-5C6920DD9142 wds:Q28508038-605FC23E-45BD-4AC9-B6A3-6CA64388A2DB wds:Q28508038-719A4392-76D6-42DE-8401-A0CFBB16F201
OpenCitations bibliographic resource ID	wds:Q28508038-91B77345-BC4F-450B-9C71-A493B95CC08D
OpenCitations bibliographic resource ID	https://w3id.org/oc/corpus/br/534333
author name string	En Li Kenichiro Hata Hiroyuki Sasaki Naomi Tsujimoto
OpenCitations bibliographic resource ID	534333
rdfs:label	Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting (en) Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting (nl) Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting (ast)
skos:prefLabel	Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting (en) Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting (nl) Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting (ast)
name	Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting (en) Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting (nl) Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting (ast)
author	wds:Q28508038-4D7DFA67-76A6-41A8-A521-2C5EEFE847F7 wds:Q28508038-C5A02BA9-3044-4CD2-BA8E-8A589801A09C wds:Q28508038-ED82C471-12F9-4FE1-B7D1-0908D08324CE
author	Takashi Sado Masahiro Kaneda Masaki Okano
title	wds:Q28508038-90E7CD8B-9766-4D2F-BA6B-E206BA452372
title	Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting (en)
page(s)	wds:Q28508038-3F89B6BD-8307-49D2-9E89-221A961B0DAB
page(s)	900-903
instance of	wds:Q28508038-4ABFFE4F-48AD-4FA3-B5BA-0440B66AC8FB
instance of	scholarly article
main subject	wds:Q28508038-5291BC47-AA44-44C9-8E97-A23650DC8845
main subject	wd:Q21108440
PubMed ID	wds:Q28508038-F511631E-2153-4CE5-94DC-E55FE8C7FFF1
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/15215868
PubMed ID	15215868
published in	wds:Q28508038-D1C4D630-0379-47AB-9D72-E43DB542C68B

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