About: tRNA modification

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The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.

Attributes	Values
rdf:type	Item
description	biologisch proces (nl) біологічний процес (uk) The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically. (en)
exact match	wds:Q21108043-9A822FB0-9018-4246-85D7-032F09618C45
exact match	http://purl.obolibrary.org/obo/GO_0006400
rdfs:label	modifikacija tRNA (sl) modifo de transdona ribonuklea acido (eo) tRNA modification (en) tRNA修飾 (ja)
skos:prefLabel	modifikacija tRNA (sl) modifo de transdona ribonuklea acido (eo) tRNA modification (en) tRNA修飾 (ja)
name	modifikacija tRNA (sl) modifo de transdona ribonuklea acido (eo) tRNA modification (en) tRNA修飾 (ja)
Gene Ontology ID	wds:Q21108043-5140FE9B-F45B-401F-A3CA-957D24D99EE7
Gene Ontology ID	GO:0006400
instance of	wds:Q21108043-F28C3C8D-91F4-4956-8426-CC9DEDE93A3C
instance of	biological process
subclass of	wds:Q21108043-2F8F4C73-0F9B-4DC5-BF5F-4A4F62704A4E wds:Q21108043-68FE0388-79AF-469D-B01B-5FDE7238E446
subclass of	RNA modification tRNA processing
skos:altLabel	GO:0006400 (en) tRNA-modifo (eo)
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q21108043
is instance of of	tRNA modification in the nucleus and cytosol Synthesis of wybutosine at G37 of tRNA(Phe) ADAT1 deaminates adenosine-37 in tRNA(Ala) EKC complex threonylcarbamoylates A37 of tRNAs METTL1:WDR4 methylates guanosine-46 of tRNA(Phe) yielding 7-methylguanosine-46 PUS3 transforms uridine-39 to pseudouridine-39 in tRNA TRMT5 methylates guanosine yielding 1-methylguanosine at nucleotide 37 of tRNA(Phe) TRMT1 (hTRM1) dimethylates guanosine-26 of tRNA(Tyr) ALKBH8 methylates 5-carboxymethyluridine-34 in tRNA(Arg) and tRNA(Glu) yielding 5-methoxycarbonylmethyluridine-34 CTU1:CTU2:URM1 thiolates uridine-34 in tRNAs DUS2:EPRS reduces uridine to dihydrouridine in tRNAs PUS7 transforms uridine to pseudouridine in tRNAs TYW1:FMN:4Fe-4S transforms 1-methylguanosine yielding yW-187 (4-demethylwyosine) at nucleotide 37 of tRNA(Phe) TRIT1 transfers dimethylallyl group to adenosine-37 of tRNAs FTSJ1 2'-O-methylates guanosine-34 in tRNA(Phe) CDKAL1:4Fe-4S methylthiolates N6-threonylcarbamoyladenosine-37 in tRNA yielding 2-methylthio-N6-threonylcarbamoyladenosine-37 PUS1 isoform 2 transforms uridine residues to pseudouridine in the anticodon stems of tRNAs KIAA1456 (TRM9L) methylates 5-carboxymethyluridine in tRNA yielding 5-methoxycarbonylmethyluridine TRMT12 transforms yW-187 yielding yW-86 at nucleotide 37 of tRNA(Phe) TYW5 hydroxylates yW-72 yielding OHyW-72 at nucleotide 37 of tRNA(Phe) TRDMT1 (DNMT2) methylates cytidine-38 of tRNA(Asp) THG1L transfers GMP to 5' end of tRNA(His) TRMT10A methylates guanosine-9 in tRNA LCMT2 methylates yW-72 yielding yW-58 at nucleotide 37 of tRNA(Phe) LCMT2 methoxycarbonylates yW-58 yielding yW (wybutosine) at nucleotide 37 of tRNA(Phe) TRMT6:TRMT61A methylate adenosine yielding 1-methyladenosine at nucleotide 58 of tRNA(Met) ADAT2:ADAT3 (hetADAT) deaminates adenosine-34 in tRNAs TRMT11:TRMT112 methylates guanosine-10 in tRNA FTSJ1 2'-O-methylates cytidine-32 in tRNA(Phe) NSUN2 methylates cytidine-34, cytidine-48 of unspliced tRNA(Leu)(CAA) NSUN2 methylates cytidine-40, cytidine-48, cytidine-49, cytidine-50 of tRNA(GLY)(GCC) NSUN2 methylates cytidine-48 and cytidine-49 of tRNA(Asp)(GUC) NSUN6 methylates cytidine-72 in tRNA(Cys) and tRNA(Thr) QTRT1:QTRTD1 exchange guanine for queuosine at guanosine-34 of tRNA(Tyr) TYW3 methylates yW-86 yielding yW-72 at nucleotide 37 of tRNA(Phe) LCMT2 methoxycarbonylates OHyW-72 yielding OHyW (hydroxywybutosine) at nucleotide 37 of tRNA(Phe) FTSJ1 2'-O-methylates cytidine-32 and guanosine-34 in tRNA(Phe)
is instance of of	wds:Q50295910-E1493529-44BF-40C8-AC6C-6A999263F395 wds:Q50295914-82856AD0-0B86-4EBF-89A4-98EDAAEC8002 wds:Q50295916-04227348-84DA-425A-9CE3-9F4ADDE29CFC wds:Q50295919-130EF893-A3AD-46CB-B79E-724FA5CA675E wds:Q50295926-DC75235A-37DA-4FE9-B0C1-DCE722CE40F2 wds:Q50295930-894C15D1-E91F-4597-8E5B-FE728EE2C16F wds:Q50295941-0E28C3CA-96AA-41BE-A9EA-E9DE4E1F2BB6 wds:Q50295931-F3DD96FD-1CF9-4EA6-B764-C771E00A3103 wds:Q50295940-57F279D2-07B6-4D4D-9172-7ACE4E2DD730 wds:Q55217347-A132912B-4A98-49DF-917F-89D61D4E872B wds:Q50295915-365A17E6-F29C-41B8-B3E2-14BBCA24E632 wds:Q50295918-06A09C5E-F26A-470E-85FD-37113A91D5F5 wds:Q50295932-05EFFC43-F56A-426F-B916-F51731F0BFA1 wds:Q50295936-F44A3955-1945-4C06-B0F9-02CFAA24AEE7 wds:Q50295938-7541F14D-4FE7-4F22-B7C2-CE4E6067754E wds:Q50295939-AE399A76-1708-4CFD-88DE-3FE26A4E8B66 wds:Q50295942-DC0DB21F-3319-4D02-80C7-CC3334108FCF wds:Q50295911-CDC26BA1-A03F-4BFA-8593-FCC64BA48428 wds:Q50295925-7521415B-3F16-4D4D-B79D-61BF748B3C68 wds:Q50295934-DC40AA67-EF9E-40C8-8EE5-3360C2DCCA07 wds:Q50295935-BD29A85D-1641-47A1-A54B-E0DBFB5B3B57 wds:Q50295944-2CD6F8D6-98FB-42DC-BF1A-B4732608E5CC wds:Q55217345-782CB088-92F9-40F1-B451-42D561602F3C wds:Q45317586-B6A47CA8-6D08-45F0-8F1E-22422AD88791 wds:Q50295922-7BD06A3A-2F93-4386-A124-E57D0B9E5872 wds:Q50295924-984E93B5-41BA-4CA6-9B9B-63EE3580ECEC wds:Q50295928-14D3F228-632B-484B-9118-B0A1720F6048 wds:Q45317588-51333B58-3520-4D1A-8C51-4D83B7D7AFD9 wds:Q50295912-B698BDC4-665E-4A8D-BA99-00C5CAB7E76F wds:Q50295920-7BF830AE-D5E4-42D8-BA8C-5E39434C5A98 wds:Q50295927-AFE6C5D4-0DFA-42DB-9428-4EA7E5AB01C7 wds:Q50295937-0DAB6AA0-AB5E-48A3-9558-28852C21970B wds:Q50295913-66B1EC61-5A66-46F8-B056-5D7F4CCB9320 wds:Q50295917-A7C9841C-35B5-4973-9B0E-1A3CA27CF5CC

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