About: lecithin cholesterol acyltransferase

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About: lecithin cholesterol acyltransferase Goto Sponge NotDistinct Permalink

An Entity of Type : wikibase:Item, within Data Space : wikidata.demo.openlinksw.com associated with source document(s)

mammalian protein found in Mus musculus

Attributes	Values
rdf:type	Item
description	protein (sv) protéine (fr) protein (id) protèin (ace) proteinë (sq) mammalian protein found in Mus musculus (en) بروتين في فأر المنازل (ar) білок ссавців, наявний у миші хатньої (uk) proteïne in Lecithin cholesterol acyltransferase (nl)
rdfs:label	lecithin cholesterol acyltransferase (en) Lecithin cholesterol acyltransferase (nl)
skos:prefLabel	lecithin cholesterol acyltransferase (en) Lecithin cholesterol acyltransferase (nl)
name	lecithin cholesterol acyltransferase (en) Lecithin cholesterol acyltransferase (nl)
instance of	wds:Q14905448-3EF4BEDE-14CF-4533-8C7F-A8C0023D3D31
part of	wds:Q14905448-2ACF0674-087D-483D-8D7C-264B90C95D74 wds:Q14905448-B638353E-AFAC-4D00-92B0-57E17991D0D7
instance of	protein
part of	Alpha/Beta hydrolase fold Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase
subclass of	wds:Q14905448-35049248-1128-412B-AB82-A5E9AC65A413
subclass of	protein
found in taxon	wds:Q14905448-BDBD9B61-BE06-4AB4-9FB4-898C34D13A0E
found in taxon	house mouse
molecular function	wds:Q14905448-052F8DD6-A347-4EF0-B091-2A0F053F6975 wds:Q14905448-32F5957B-FC48-4DAE-9511-8DB8BD166918 wds:Q14905448-725F7685-4BBA-4004-915B-4636B31426BD wds:Q14905448-887C4E84-73EF-40D0-8E91-53F551FF796F wds:Q14905448-99CE5667-A580-4232-836E-C9D16CD5349D wds:Q14905448-BA123C9B-A3B7-495E-929D-3D5D26D7FAED
molecular function	transferase activity acyltransferase activity O-acyltransferase activity apolipoprotein A-I binding phosphatidylcholine-sterol O-acyltransferase activity phospholipase A2 activity
cell component	wds:Q14905448-323E895A-6E63-42BB-8664-28E3D79F858F wds:Q14905448-5A28A72E-EDF8-4F68-9281-5F649D1619EB wds:Q14905448-907BC8E1-2931-47C5-9032-17734988066E
cell component	extracellular region extracellular space high-density lipoprotein particle
skos:altLabel	Lcat (en) lecithin-cholesterol acyltransferase (en) phosphatidylcholine-sterol acyltransferase (en) phospholipid-cholesterol acyltransferase (en) 1-alkyl-2-acetylglycerophosphocholine esterase (en) PAF acetylhydrolase (en) platelet-activating factor acetylhydrolase (en) lecithin-cholesterol acyltransferase Lcat (en)
UniProt protein ID	wds:Q14905448-FD603470-B98F-4258-B1A3-62782EDA3A20
RefSeq protein ID	wds:Q14905448-45860613-2BBC-46D5-9FA9-0FD2157C7F43
biological process	wds:Q14905448-01638A86-2DE2-4B38-9CD5-E7AA5D9ABE1C wds:Q14905448-02497D69-8E6D-4284-BFA1-E370B7B11BA2 wds:Q14905448-0EB44546-26BC-48BE-9058-6CB2AEFBC62B wds:Q14905448-14729B09-52CB-4926-9A7A-1E93675B4D37 wds:Q14905448-17061C68-72DF-4DFF-B78A-C9ED62FAF4E0 wds:Q14905448-1FB43A91-C2AF-4158-801A-E77C29DB6E6B wds:Q14905448-34F1FBC7-6D13-4F94-8918-0B1466D73784 wds:Q14905448-39C92A2A-27DF-46F9-B29A-0B5A43D844DB wds:Q14905448-559F44F6-1FCA-410D-9DA2-6ACD7DA632FC wds:Q14905448-690FDB95-DB68-4AEE-A3DA-A7C3E4C7CC78 wds:Q14905448-73D33C00-9BD8-4FAD-AB76-CB6307A192B7 wds:Q14905448-8397DDEA-AA64-44AF-84F1-F4CA9E15E571 wds:Q14905448-E4964A3C-B69D-49B0-8693-1D3241CCC81A wds:Q14905448-E776DCD4-543E-472D-A40E-E9BAEE2F87A5 wds:Q14905448-F323C275-E0F4-40CA-B24E-FC38100B32F0 wds:Q14905448-F46B4E3C-B2D7-4256-8EBD-FEF190E7E39A wds:Q14905448-FF7D5ADF-41DB-4B9B-B4FE-2A7D15DF6B3F
encoded by	wds:Q14905448-2B022159-EB60-441C-88FE-CFB5E0A36638
Ensembl protein ID	wds:Q14905448-D0BBCFB5-2356-4636-9F9F-829A69C9ACAE
UniProt protein ID	uniprot:uniprot/P16301
RefSeq protein ID	uniprot:refseq/NP_032516
UniProt protein ID	P16301
RefSeq protein ID	NP_032516
biological process	lipid metabolism reverse cholesterol transport response to glucocorticoid steroid metabolic process cholesterol metabolic process cholesterol transport cholesterol homeostasis very-low-density lipoprotein particle remodeling lipoprotein metabolic process high-density lipoprotein particle remodeling lipoprotein biosynthetic process phospholipid metabolic process cholesterol esterification phosphatidylcholine biosynthetic process phosphatidylcholine metabolic process regulation of high-density lipoprotein particle assembly response to copper ion
encoded by	Lcat
Ensembl protein ID	ENSMUSP00000038232
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q14905448
is main subject of	Point mutations in apolipoprotein A-I mimic the phenotype observed in patients with classical lecithin:cholesterol acyltransferase deficiency Adenoviral vector-mediated overexpression of serum amyloid A in apoA-I-deficient mice Inhibition of intimal lipid deposition in human apolipoprotein A1 transgenic mice

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