About: Increased expression of type 2 3alpha-hydroxysteroid dehydrogenase/type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3) and its relationship with androgen receptor in prostate carcinoma

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About: Increased expression of type 2 3alpha-hydroxysteroid dehydrogenase/type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3) and its relationship with androgen receptor in prostate carcinoma Goto Sponge NotDistinct Permalink

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scientific article published on 01 March 2006

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в березні 2006 (uk) artículu científicu espublizáu en marzu de 2006 (ast) scientific article published on 01 March 2006 (en)
publication date	wds:Q83118257-F92B45DB-A1B0-4440-B4DE-BE0550BE96A7
publication date	2006-03-01 00:00:00Z (xsd:dateTime)
author name string	wds:Q83118257-081FFB6E-A3AA-458C-8198-0743A2AEE94F wds:Q83118257-221B5B2D-2D06-41F3-9681-ECD1F8680D5E wds:Q83118257-2B357DEB-35AF-449D-B587-52E425706229 wds:Q83118257-3B020C71-EFBB-4CDD-96F1-16FE9510C2EF wds:Q83118257-52ADC148-E316-4EB6-95F3-8030D61F42D9 wds:Q83118257-81A0C90A-FF86-41B7-BAFB-8CF045FA5C20 wds:Q83118257-836AACB4-FCD3-482C-8678-7992F38A9F50 wds:Q83118257-8A9868A8-B149-4A3F-BFFB-7A40DD4F4EAC wds:Q83118257-8DD87AEF-47A0-46E4-AE0E-6EAEB219ED9E wds:Q83118257-C5DA3624-BBE8-4A9E-9150-ADD28D45D417 wds:Q83118257-EAFBD73E-64BA-4C0A-8512-42490F36E79D
author name string	J T Yang C Wong B P Kropp B Bane Hsueh-Kung Lin D J Culkin J V Pitha E N S Samara K-M Fung A Metwalli R Krlin
rdfs:label	Increased expression of type 2 3alpha-hydroxysteroid dehydrogenase/type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3) and its relationship with androgen receptor in prostate carcinoma (en) Increased expression of type 2 3alpha-hydroxysteroid dehydrogenase/type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3) and its relationship with androgen receptor in prostate carcinoma (nl)
skos:prefLabel	Increased expression of type 2 3alpha-hydroxysteroid dehydrogenase/type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3) and its relationship with androgen receptor in prostate carcinoma (en) Increased expression of type 2 3alpha-hydroxysteroid dehydrogenase/type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3) and its relationship with androgen receptor in prostate carcinoma (nl)
name	Increased expression of type 2 3alpha-hydroxysteroid dehydrogenase/type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3) and its relationship with androgen receptor in prostate carcinoma (en) Increased expression of type 2 3alpha-hydroxysteroid dehydrogenase/type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3) and its relationship with androgen receptor in prostate carcinoma (nl)
author	wds:Q83118257-2216F6E7-4D7F-4E91-A85C-A4A2CBAC4547 wds:Q83118257-E2E70B44-DBB3-4CB4-AE2E-31E17119305F
author	Trevor M Penning Cheng Z Liu
title	wds:Q83118257-CE8863A2-86BE-4F6D-AB46-5345D4924DAB
title	Increased expression of type 2 3alpha-hydroxysteroid dehydrogenase/type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3) and its relationship with androgen receptor in prostate carcinoma (en)
page(s)	wds:Q83118257-71B4DA59-D03B-4E23-8830-55714CC979F3
page(s)	169-180
instance of	wds:Q83118257-BE378A1D-3BB3-49A0-AAFE-C69EFFD86E14
instance of	scholarly article
main subject	wds:Q83118257-B7A9A3BE-9BE1-482C-B4C9-C848281F740A
main subject	prostate carcinoma
PubMed ID	wds:Q83118257-370BD128-E18D-48F0-B97E-E038FBB33E38
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/16601286
PubMed ID	16601286
published in	wds:Q83118257-06F7E376-D414-4D96-BB17-92A3F39F6ED0
published in	Endocrine-Related Cancer
issue	wds:Q83118257-4910401A-0854-4648-93D0-F2B9D13D134A
volume	wds:Q83118257-1A04EB07-0221-4C74-8CA5-C618E3CCE2EA
issue	1
volume	13
DOI	wds:Q83118257-20534809-C905-4D17-BFA0-7496540240CD
DOI	http://dx.doi.org/10.1677/ERC.1.01048
DOI	10.1677/ERC.1.01048
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q83118257
is cites work of	Involvement of an aldo-keto reductase (AKR1C3) in redox cycling of 9,10-phenanthrenequinone leading to apoptosis in human endothelial cells Interleukin-6 regulates androgen synthesis in prostate cancer cells Evolution of androgen receptor targeted therapy for advanced prostate cancer Elevated AKR1C3 expression promotes prostate cancer cell survival and prostate cell-mediated endothelial cell tube formation: implications for prostate cancer progression New frontiers in androgen biosynthesis and metabolism. An indomethacin analogue, N-(4-chlorobenzoyl)-melatonin, is a selective inhibitor of aldo-keto reductase 1C3 (type 2 3alpha-HSD, type 5 17beta-HSD, and prostaglandin F synthase), a potential target for the treatment of hormone dependent and hormone Identification of hypoxia-induced genes in a malignant glioma cell line (U-251) by cDNA microarray analysis. Steroid hormone synthetic pathways in prostate cancer Classical and Non-Classical Roles for Pre-Receptor Control of DHT Metabolism in Prostate Cancer Progression Mechanisms of drug resistance that target the androgen axis in castration resistant prostate cancer (CRPC). Overexpression of aldo-keto reductase 1C3 (AKR1C3) in LNCaP cells diverts androgen metabolism towards testosterone resulting in resistance to the 5α-reductase inhibitor finasteride. Discovery of substituted 3-(phenylamino)benzoic acids as potent and selective inhibitors of type 5 17β-hydroxysteroid dehydrogenase (AKR1C3). Human hydroxysteroid dehydrogenases and pre-receptor regulation: insights into inhibitor design and evaluation. AKR1C2 and AKR1C3 mediated prostaglandin D2 metabolism augments the PI3K/Akt proliferative signaling pathway in human prostate cancer cells Steroid hormone transforming aldo-keto reductases and cancer Developmental evaluation of aldo-keto reductase 1C3 expression in the cryptorchid testis Differential expression of type 2 3α/type 5 17β-hydroxysteroid dehydrogenase (AKR1C3) in tumors of the central nervous system. Expression of AKR1C3 in renal cell carcinoma, papillary urothelial carcinoma, and Wilms' tumor Aldo-keto reductase family 1 member C3 (AKR1C3) is expressed in adenocarcinoma and squamous cell carcinoma but not small cell carcinoma. Expression of aldo-keto reductase family 1 member C3 (AKR1C3) in neuroendocrine tumors & adenocarcinomas of pancreas, gastrointestinal tract, and lung A Role for the PPARgamma in Cancer Therapy. Suppressed expression of type 2 3alpha/type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3) in endometrial hyperplasia and carcinoma. Role of aldo-keto reductase family 1 (AKR1) enzymes in human steroid metabolism Androgen biosynthesis in castration-resistant prostate cancer Galectin-1 and its involvement in hepatocellular carcinoma aggressiveness Brain tumor hypoxia: tumorigenesis, angiogenesis, imaging, pseudoprogression, and as a therapeutic target Tissue distribution of human AKR1C3 and rat homolog in the adult genitourinary system KLF15 Is a transcriptional regulator of the human 17beta-hydroxysteroid dehydrogenase type 5 gene. A potential link between regulation of testosterone production and fat stores in women Castration-resistant prostate cancer: targeting androgen metabolic pathways in recurrent disease Intracrine androgen metabolism in prostate cancer progression: mechanisms of castration resistance and therapeutic implications AKR1C3 overexpression may serve as a promising biomarker for prostate cancer progression In vitro and in vivo characterisation of ASP9521: a novel, selective, orally bioavailable inhibitor of 17β-hydroxysteroid dehydrogenase type 5 (17βHSD5; AKR1C3). Pomegranate polyphenols down-regulate expression of androgen-synthesizing genes in human prostate cancer cells overexpressing the androgen receptor Knockdown of AKR1C3 exposes a potential epigenetic susceptibility in prostate cancer cells Regulation of local steroidogenesis in the brain and in prostate cancer: lessons learned from interdisciplinary collaboration. Regulation of aldo-keto reductases in human diseases Frankincense essential oil prepared from hydrodistillation of Boswellia sacra gum resins induces human pancreatic cancer cell death in cultures and in a xenograft murine model Riboflavin deficiency induces a significant change in proteomic profiles in HepG2 cells Expression of AKR1C3 and CNN3 as markers for detection of lymph node metastases in colorectal cancer. AKR1C3 is a biomarker of sensitivity to PR-104 in preclinical models of T-cell acute lymphoblastic leukemia

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