About: The inflammatory/cancer-related IL-6/STAT3/NF-κB positive feedback loop includes AUF1 and maintains the active state of breast myofibroblasts

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About: The inflammatory/cancer-related IL-6/STAT3/NF-κB positive feedback loop includes AUF1 and maintains the active state of breast myofibroblasts Goto Sponge NotDistinct Permalink

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scientific article published on 26 May 2016

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description	videnskabelig artikel (da) article científic (ca) articolo scientifico (it) artigo científico (pt) bilimsel makale (tr) vedecký článok (sk) vetenskaplig artikel (sv) vědecký článek (cs) wetenschappelijk artikel (nl) wissenschaftlicher Artikel (de) научни чланак (sr) article scientifique (fr) artículu científicu espublizáu en 2016 (ast) наукова стаття, опублікована в травні 2016 (uk) مقالة علمية نشرت في 26 مايو 2016 (ar) scientific article published on 26 May 2016 (en)
publication date	wds:Q37520409-A84881CB-1067-48A0-82CB-58A67C619004
publication date	2016-05-26 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q37520409-453E16BF-024A-459A-A86B-DB46A8FB6302
language of work or name	English
cites work	wds:Q37520409-137F3D94-EF83-4F0F-88C6-AFD07CDC20F8 wds:Q37520409-1C9EBCB9-5641-432B-A507-31B82A07C719 wds:Q37520409-1DA95E9D-A37D-4ECF-B8D2-BF30AAA9F704 wds:Q37520409-23E942AC-EE73-4F65-8762-49729CCE5C09 wds:Q37520409-2653AFF3-8C9B-45DF-98F0-49D0917120AD wds:Q37520409-2D13A719-E0BC-400D-A3F0-4C5A77E6AA88 wds:Q37520409-36B79D4B-A042-4ED9-96B5-3F1940132344 wds:Q37520409-38A8408C-9843-4899-9DC6-AE9A55EEBE5D wds:Q37520409-39FE2FCC-0B70-4270-80AA-31F483EBA7E1 wds:Q37520409-3A9BAE81-7078-4DD8-8433-CBA22A4D8006 wds:Q37520409-53134540-643A-48A9-A963-64756AD09B1F wds:Q37520409-5413982A-5D6B-4E75-AD65-F92C96564F1F wds:Q37520409-59995280-2C6C-402F-8CEB-F1170192831F wds:Q37520409-5C5E2C95-CA74-428F-9BE2-FCCC0FB03FB5 wds:Q37520409-6100BF0F-357D-493E-8AB8-0CA082836488 wds:Q37520409-6261C4B0-25A2-4F87-B619-721DA066156B wds:Q37520409-6401E531-8EF7-491B-9803-63E0D879CA3C wds:Q37520409-76536F20-A102-4A51-B802-0F0885CDCEFB wds:Q37520409-887B9862-2C54-4AA7-AE06-AC8B2192A72C wds:Q37520409-8CA01225-DC8F-41E8-B3DD-316A8E918B26 wds:Q37520409-91127210-5C9D-43FE-BDE5-DEE9AF27321B wds:Q37520409-94E4FFEB-0FE3-40D4-B5C1-76300BFA5E42 wds:Q37520409-A613FA11-A820-4338-8BD9-34B010E8BAD1 wds:Q37520409-AFDD06BF-2E05-4CCB-BC53-AA02F1C310E1 wds:Q37520409-B670B558-0B4E-4A94-BF0A-F6CF18283C77 wds:Q37520409-BCBD6FE8-7D1F-48AD-9F46-4A06995BE7DC wds:Q37520409-CA4CEAEB-FBFE-4EA8-BA9B-CE61A2C7B0D0 wds:Q37520409-E53B0519-67F1-4653-9E8E-598ADD0EF560 wds:Q37520409-E5FCCCB0-4313-4CC7-B5DC-4D44C3B8C82C wds:Q37520409-E95F9B0A-2FDF-4C39-B945-90F97C5B64FF wds:Q37520409-F92E5D69-695B-4A50-8085-8BD604BDBF76 wds:Q37520409-FAA89B2E-4382-4586-A5DE-3B69393FE81A wds:Q37520409-FB40CF3A-B0B3-4066-A2D5-C0793DE21E31 wds:Q37520409-FE279245-8146-4B22-865F-00876CD584C1 wds:Q37520409-FF2158A5-A8F7-4AC7-9CBF-09B7CF30439D
cites work	p16(INK4A) represses the paracrine tumor-promoting effects of breast stromal fibroblasts. The role of intratumoral and systemic IL-6 in breast cancer Oestrogen receptor negative breast cancers exhibit high cytokine content Stat3 is tyrosine-phosphorylated through the interleukin-6/glycoprotein 130/Janus kinase pathway in breast cancer. Tissue microarray analysis of signal transducers and activators of transcription 3 (Stat3) and phospho-Stat3 (Tyr705) in node-negative breast cancer shows nuclear localization is associated with a better prognosis Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer Breast carcinoma-associated fibroblasts and their counterparts display neoplastic-specific changes. An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation Pten in stromal fibroblasts suppresses mammary epithelial tumours The role of the microenvironment in mammary gland development and cancer Genomic Alterations in Tumor Stroma Lin28 promotes transformation and is associated with advanced human malignancies Cancer-associated fibroblasts: a multifaceted driver of breast cancer progression Distinct epigenetic changes in the stromal cells of breast cancers Breast cancer DNA methylation profiles in cancer cells and tumor stroma: association with HER-2/neu status in primary breast cancer. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion Prognostic value of serum levels of interleukin 6 and of serum and plasma levels of vascular endothelial growth factor in hormone-refractory metastatic breast cancer patients Curcumin triggers p16-dependent senescence in active breast cancer-associated fibroblasts and suppresses their paracrine procarcinogenic effects Lin28: primal regulator of growth and metabolism in stem cells Carcinoma-associated fibroblasts: non-neoplastic tumour-promoting mesenchymal cells. Double-negative feedback loop between reprogramming factor LIN28 and microRNA let-7 regulates aldehyde dehydrogenase 1-positive cancer stem cells Association of coffee consumption with serum adiponectin, leptin, inflammation and metabolic markers in Japanese workers: a cross-sectional study. Molecular biology of cancer-associated fibroblasts: can these cells be targeted in anti-cancer therapy? Clonal Mutations in the Cancer-Associated Fibroblasts: The Case against Genetic Coevolution Cancer associated fibroblasts in cancer pathogenesis Caffeine mediates sustained inactivation of breast cancer-associated myofibroblasts via up-regulation of tumor suppressor genes LIN28/LIN28B: an emerging oncogenic driver in cancer stem cells Increased stability of the p16 mRNA with replicative senescence The cytokine IL-6 reactivates breast stromal fibroblasts through transcription factor STAT3-dependent up-regulation of the RNA-binding protein AUF1. The p16INK4a tumor suppressor controls p21WAF1 induction in response to ultraviolet light Role of cancer-associated fibroblasts in breast cancer development and prognosis The impact of tumor stroma on drug response in breast cancer Caffeine and Caffeic Acid Inhibit Growth and Modify Estrogen Receptor and Insulin-like Growth Factor I Receptor Levels in Human Breast Cancer Constitutive phosphorylated STAT3-associated gene signature is predictive for trastuzumab resistance in primary HER2-positive breast cancer
author name string	wds:Q37520409-24E39797-BBA2-4111-B2EA-9DD099ED4402 wds:Q37520409-5A19AA79-AC43-4E5C-B994-513C5DEF73BA wds:Q37520409-F5E663BA-A260-4D42-878C-A8A02574807C
author name string	Abdelilah Aboussekhra Siti-Fauziah Hendrayani Bothaina Al-Harbi
rdfs:label	The inflammatory/cancer-related IL-6/STAT3/NF-κB positive feedback loop includes AUF1 and maintains the active state of breast myofibroblasts. (nl) The inflammatory/cancer-related IL-6/STAT3/NF-κB positive feedback loop includes AUF1 and maintains the active state of breast myofibroblasts (en) The inflammatory/cancer-related IL-6/STAT3/NF-κB positive feedback loop includes AUF1 and maintains the active state of breast myofibroblasts (ast)

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