About: Altohyrtins B and C and 5-desacetylaltohyrtin A, potent cytotoxic macrolide congeners of altohyrtin A, from the Okinawan marine sponge Hyrtios altum

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About: Altohyrtins B and C and 5-desacetylaltohyrtin A, potent cytotoxic macrolide congeners of altohyrtin A, from the Okinawan marine sponge Hyrtios altum Goto Sponge NotDistinct Permalink

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scientific article published on 01 May 1993

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в травні 1993 (uk) im Mai 1993 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en mayu de 1993 (ast) scientific article published on 01 May 1993 (en)
publication date	wds:Q72852099-CB6FA2C9-2805-418E-B253-5914E6B2871F
publication date	1993-01-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q72852099-81EFFB71-A816-48FB-9281-F56D8B3C6030
language of work or name	English
access restriction status	wds:Q72852099-6B660DFF-645A-40F7-B619-6AFBC61E685F
access restriction status	open access
author name string	wds:Q72852099-41326C1D-5C34-4A71-A5C2-0CC23F921B9B wds:Q72852099-4E9AB7C4-9111-4E2A-84BA-F978C6312D51 wds:Q72852099-541729AE-EA3D-400B-A2AE-DA2A7FD47C09 wds:Q72852099-546A6ED3-0C8C-4293-AA7D-74CE9C0DC576 wds:Q72852099-7B82A084-DCAB-470A-9E22-0FE48C933CF5 wds:Q72852099-B9889E13-240C-43C0-8836-AD6D2BEE59AE
author name string	M Kobayashi S Aoki T Sasaki H Sakai I Kitagawa N Kihara
rdfs:label	Altohyrtins B and C and 5-desacetylaltohyrtin A, potent cytotoxic macrolide congeners of altohyrtin A, from the Okinawan marine sponge Hyrtios altum (en) Altohyrtins B and C and 5-desacetylaltohyrtin A, potent cytotoxic macrolide congeners of altohyrtin A, from the Okinawan marine sponge Hyrtios altum (nl)
skos:prefLabel	Altohyrtins B and C and 5-desacetylaltohyrtin A, potent cytotoxic macrolide congeners of altohyrtin A, from the Okinawan marine sponge Hyrtios altum (en) Altohyrtins B and C and 5-desacetylaltohyrtin A, potent cytotoxic macrolide congeners of altohyrtin A, from the Okinawan marine sponge Hyrtios altum (nl)
name	Altohyrtins B and C and 5-desacetylaltohyrtin A, potent cytotoxic macrolide congeners of altohyrtin A, from the Okinawan marine sponge Hyrtios altum (en) Altohyrtins B and C and 5-desacetylaltohyrtin A, potent cytotoxic macrolide congeners of altohyrtin A, from the Okinawan marine sponge Hyrtios altum (nl)
title	wds:Q72852099-4C87BCDF-CF49-4680-931F-BB76E73D71F0
title	Altohyrtins B and C and 5-desacetylaltohyrtin A, potent cytotoxic macrolide congeners of altohyrtin A, from the Okinawan marine sponge Hyrtios altum (en)
page(s)	wds:Q72852099-0F99E672-3925-44BD-B7FD-0543BC08F2F6
page(s)	989-991
instance of	wds:Q72852099-A2775C19-6F25-4E48-924C-BB64B5D4112C
instance of	scholarly article
main subject	wds:Q72852099-B116BF52-C32F-459F-A558-19F3A685D4AA wds:Q72852099-CBA3622F-161E-4275-91CA-3B5E81FCECC5 wds:Q72852099-E202FDFE-C62C-4B47-A0EF-5CCB78CDD76D wds:Q72852099-E2604531-D340-4C4E-AB5C-3E3983771F7F
main subject	OBLCEVLAQAFINR-CMVVSLHSSA-N Altohyrtin B Hyrtios altus ICXJVZHDZFXYQC-LLCCCFLLSA-N
PubMed ID	wds:Q72852099-8168C399-F68D-4481-9FEB-708178F80B96
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/8339346
PubMed ID	8339346
published in	wds:Q72852099-75564D4B-D400-4230-A4F2-5836BAB9BBB5
full work available at URL	wds:Q72852099-6BFF92EE-FF3C-43EE-85EF-2659BA5717B2
published in	Chemical & Pharmaceutical Bulletin
full work available at URL	https://www.jstage.jst.go.jp/article/cpb1958/41/5/41_5_989/_pdf
issue	wds:Q72852099-2276BBB8-33F7-46AD-946E-B2ACCD4959D8
volume	wds:Q72852099-C929389C-ECAE-44C4-A293-B43C89938BC0
issue	5
volume	41
DOI	wds:Q72852099-1AC34453-6413-4630-8E32-97C8C6A96B7D
DOI	http://dx.doi.org/10.1248/CPB.41.989
DOI	10.1248/CPB.41.989
online access status	wds:Q72852099-C98AC90E-927C-4977-97D6-0872A7935548
online access status	open access
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q72852099
is cites work of	Antifungal peroxyketal acids from an Okinawan marine sponge of Plakortis sp. The Role of Spongia sp. in the Discovery of Marine Lead Compounds Marine natural products. XXXII. Absolute configurations of C-4 of the manoalide family, biologically active sesterterpenes from the marine sponge Hyrtios erecta Marine natural products. XXXIV. Trisindoline, a new antibiotic indole trimer, produced by a bacterium of Vibrio sp. separated from the marine sponge Hyrtios altum Marine natural products Marine natural products Advances in the total synthesis of biologically important marine macrolides Marine natural products Nonanomeric spiroketals in natural products: structures, sources, and synthetic strategies Ceftazidime. An update of its antibacterial activity, pharmacokinetic properties and therapeutic efficacy Kotalanol, a potent alpha-glucosidase inhibitor with thiosugar sulfonium sulfate structure, from antidiabetic ayurvedic medicine Salacia reticulata. Total Synthesis of Spongistatin 1: A Synthetic Strategy Exploiting Its Latent Pseudo-Symmetry Spongistatin synthetic studies. An efficient, second-generation construction of an advanced ABCD intermediate Racemization in Prins cyclization reactions Toxins affecting actin filaments and microtubules New efficient route to an advanced precursor of the AB spiroketal of spongistatins Hyrtioerectines A-C, cytotoxic alkaloids from the red sea sponge hyrtioserectus. Gram-scale synthesis of (+)-spongistatin 1: development of an improved, scalable synthesis of the F-ring subunit, fragment union, and final elaboration Toward a more step-economical and scalable synthesis of spongistatin 1 to facilitate cancer drug development efforts Complex fragment coupling by crotylation: A powerful tool for polyketide natural product synthesis Spongipyran Synthetic Studies. Total Synthesis of (+)-Spongistatin 2. Exploiting pseudo C2-symmetry for an efficient synthesis of the F-ring of the spongistatins Synthesis of a C(29)-C(51) subunit of spongistatin 1 (Altohyrtin A) starting from (R)-3-benzyloxy-2-methylpropan-1-ol Synthesis of the C(29)-C(45) bis-pyran subunit (E-F) of spongistatin 1 (Altohyrtin A) The Spongistatins: Architecturally Complex Natural Products-Part One: A Formal Synthesis of (+)-Spongistatin 1 by Construction of an Advanced ABCD Fragment Financial support was provided by the National Institutes of Health (National Cancer Institut Asymmetric total synthesis of spongistatins 1 and 2 Stereocontrolled Total Synthesis of (+)-Altohyrtin A/Spongistatin 1 Financial support was provided by the EPSRC (GR/L41646), Cambridge Commonwealth Trust (Scholarship to M.J.C.), EC (Marie Curie Postdoctoral Fellowship to J.L.A.), DFG (Postdoctoral A modular approach to marine macrolide construction. 4. Assembly of C36-C51 and C29-C44 building blocks and evaluation of key coupling reactions targeting spongistatin 1 (altohyrtin A) The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: the AB-spiroacetal segment Secondary metabolites from marine microorganisms A Practical and Efficient Synthesis of the C-16−C-28 Spiroketal Fragment (CD) of the Spongistatins Hyrtiazepine, an azepino-indole-type alkaloid from the Red Sea marine sponge Hyrtios erectus. Sesterterpenoids from the marine sponge Hyrtios erectus Marine macrolides, a promising source of antitumor compounds. A Second-Generation Synthesis of the C1−C28 Portion of the Altohyrtins (Spongistatins) Spongistatin synthetic studies. evolution of a scalable synthesis for the EF fragment of (+)-Spongistatin 1 exploiting a Petasis-Ferrier union/rearrangement tactic Total synthesis of (+)-spongistatin 1. An effective second-generation construction of an advanced EF Wittig salt, fragment union, and final elaboration A New Bioactive Metabolite Isolated from the Red Sea Marine Sponge Hyrtios erectus. Three new cytotoxic sesterterpenes from the marine sponge Hyrtios cf. erectus

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