About: The antileishmanial activity of novel oxygenated chalcones and their mechanism of action

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About: The antileishmanial activity of novel oxygenated chalcones and their mechanism of action Goto Sponge NotDistinct Permalink

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scientific article published on 01 June 1999

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в червні 1999 (uk) im Juni 1999 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en xunu de 1999 (ast) scientific article published on 01 June 1999 (en)
publication date	wds:Q57633720-27405E8E-753B-47D8-839D-6A686BC33468
publication date	1999-06-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q57633720-F1AA64EF-776C-443D-9031-3037999F4090
language of work or name	English
cites work	wds:Q57633720-226466E6-3B53-4FB7-BC92-9FF9321F6FE8 wds:Q57633720-2E573D7A-5596-43DD-9BA7-35EF6BEB301D wds:Q57633720-3208D413-698C-44B3-ACBA-9B0D23B11740 wds:Q57633720-7D545980-1544-4047-A764-98170C547BFF wds:Q57633720-A052B69E-5ABE-4375-8BD0-E6726336B969 wds:Q57633720-A71A9A2E-E2F6-428B-A787-36AB460F4D4C wds:Q57633720-AB73ECF9-DCEA-4D9A-81EC-B8E34AF7E1D3 wds:Q57633720-E4CEA14C-7DC8-40E1-A380-90097BBA96BA wds:Q57633720-F7FD00E1-AC0C-4BC8-9F09-E4F715F3347B
cites work	In vitro antimalarial activity of chalcones and their derivatives Practical progress and new drugs for changing patterns of leishmaniasis AIDS and Leishmania infantum. New approaches for a new epidemiological problem Antileishmanial activity of licochalcone A in mice infected with Leishmania major and in hamsters infected with Leishmania donovani Licochalcone A, a novel antiparasitic agent with potent activity against human pathogenic protozoan species of Leishmania The novel oxygenated chalcone, 2,4-dimethoxy-4'-butoxychalcone, exhibits potent activity against human malaria parasite Plasmodium falciparum in vitro and rodent parasites Plasmodium berghei and Plasmodium yoelii in vivo Effects of beta-lapachone, a peroxide-generating quinone, on macromolecule synthesis and degradation in Trypanosoma cruzi The antileishmanial agent licochalcone A interferes with the function of parasite mitochondria The use of a water-soluble formazan complex to quantitate the cell number and mitochondrial function of Leishmania major promastigotes.
author name string	wds:Q57633720-28E7EC2B-1EFD-425E-BF7A-03D3B560B567 wds:Q57633720-777B7255-137E-4B83-BFAF-313189469B52 wds:Q57633720-883B39E1-27BD-44D2-BBD5-A373128AE75F wds:Q57633720-B823EE09-8254-43EB-B2BB-FA48FAFF867B
author name string	M Chen L Zhai J Blom A Kharazmi
rdfs:label	The antileishmanial activity of novel oxygenated chalcones and their mechanism of action (en) The antileishmanial activity of novel oxygenated chalcones and their mechanism of action (nl)
skos:prefLabel	The antileishmanial activity of novel oxygenated chalcones and their mechanism of action (en) The antileishmanial activity of novel oxygenated chalcones and their mechanism of action (nl)
name	The antileishmanial activity of novel oxygenated chalcones and their mechanism of action (en) The antileishmanial activity of novel oxygenated chalcones and their mechanism of action (nl)
author	wds:Q57633720-895AB587-FB22-40C5-9AAC-1BD105B76B1B wds:Q57633720-93CC40D9-CD87-421A-8F34-FDA36BAA4EB2
author	Thor G. Theander Søren Brøgger Christensen
title	wds:Q57633720-ECB2A521-2A84-46E7-AC6F-ADE430C1AD5F
title	The antileishmanial activity of novel oxygenated chalcones and their mechanism of action (en)
page(s)	wds:Q57633720-E356D1C2-5AFD-4579-87A0-30595A610B8C
page(s)	793-803
instance of	wds:Q57633720-B21B8124-A0B4-48A3-9E97-A840B8C2C355
instance of	scholarly article
PubMed ID	wds:Q57633720-1062F15F-6656-4E22-805C-F367F859E650
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/10404318
PubMed ID	10404318
published in	wds:Q57633720-A9FAFD93-18E4-4F56-A88D-499DCB49ED69
published in	Journal of Antimicrobial Chemotherapy
issue	wds:Q57633720-68765340-321D-42FE-87CD-D4905515E0E8
volume	wds:Q57633720-A5F122EB-CA44-4082-87B3-04C0213A5ECB
issue	6
volume	43
number of pages	wds:Q57633720-0BEEE889-DC58-44AB-A81A-D14472F0E6FB
number of pages	11 (xsd:decimal)
DOI	wds:Q57633720-6FB43ECE-F7F8-455E-BD93-93143753DF8D
DOI	http://dx.doi.org/10.1093/JAC/43.6.793
DOI	10.1093/JAC/43.6.793
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q57633720
is cites work of	Antileishmanial activity of an indole alkaloid from Peschiera australis Investigational drugs for visceral leishmaniasis Clinical and experimental advances in treatment of visceral leishmaniasis Antiplasmodial chalcones inhibit sorbitol-induced hemolysis of Plasmodium falciparum-infected erythrocytes (E)-1-Ferrocenyl-3-(3-nitro-phen-yl)prop-2-en-1-one (E)-1-Ferrocenyl-3-(2-fur-yl)prop-2-en-1-one (E)-1-Ferrocenyl-3-phenyl-prop-2-en-1-one Structure-activity relationships of antileishmanial and antimalarial chalcones Chalcones from Chinese liquorice inhibit proliferation of T cells and production of cytokines. The antiparasitic compound licochalcone a is a potent echinocytogenic agent that modifies the erythrocyte membrane in the concentration range where antiplasmodial activity is observed. Inhibition of fumarate reductase in Leishmania major and L. donovani by chalcones. Polymeric colloidal particulate systems: intelligent tools for intracellular targeting of antileishmanial cargos 1,1-Diphenyl,2-picrylhydrazyl free radical scavenging, bactericidal, fungicidal and leishmanicidal properties of Teucrium stocksianum Focus on PAINS: false friends in the quest for selective anti-protozoal lead structures from Nature? Activity of synthetic chalcones in hamsters experimentally infected with Leishmania (Viannia) braziliensis. Altered sterol profile induced in Leishmania amazonensis by a natural dihydroxymethoxylated chalcone. Solvent free synthesis of 1,3-diaryl-2-propenones catalyzed by commercial acid-clays under ultrasound irradiation Promising therapeutic targets for antileishmanial drugs Antileishmanial, Antimicrobial and Antifungal Activities of Some New Aryl Azomethines A lupane-triterpene isolated from Combretum leprosum Mart. fruit extracts that interferes with the intracellular development of Leishmania (L.) amazonensis in vitro Anti-Trichomonas vaginalis activity of chalcone and amino-analogues Aurapten, a coumarin with growth inhibition against Leishmania major promastigotes 3-Phenyl-1-(pyrrol-2-yl)prop-2-en-1-one Trypanocidal and leishmanicidal properties of substitution-containing chalcones The Role of Natural Products in Drug Discovery and Development against Neglected Tropical Diseases Antileishmanial, DNA Interaction, and Docking Studies of Some Ferrocene-Based Heteroleptic Pentavalent Antimonials. Effects of licochalcone A on the bioavailability and pharmacokinetics of nifedipine in rats: possible role of intestinal CYP3A4 and P-gp inhibition by licochalcone A. Emerging therapeutic targets for treatment of leishmaniasis. In vitro biotransformation, in vivo efficacy and pharmacokinetics of antimalarial chalcones. Contribution of Natural Products to Drug Discovery in Tropical Diseases N-[(E,Z)-1,3-Diphenyl-prop-2-enyl-idene]-N'-(1,3-dithio-lan-2-yl-idene)hydrazine (E)-1-Ferrocenyl-3-(4-methoxy-phen-yl)-prop-2-en-1-one Conformation analysis of a novel fluorinated chalcone.

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