About: A GTPase-activating protein controls Rab5 function in endocytic trafficking

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scientific article published on 07 August 2005

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) article scientifique publié en 2005 (fr) наукова стаття, опублікована в серпні 2005 (uk) artículu científicu espublizáu n'agostu de 2005 (ast) scientific article published on 07 August 2005 (en)
publication date	wds:Q81019228-35753910-5F26-4854-A8B0-802C5B5DA19C
publication date	2005-08-07 00:00:00Z (xsd:dateTime)
exact match	wds:Q81019228-56E960BD-6A50-4770-B7FF-D74FA2995F19
exact match	https://scigraph.springernature.com/pub.10.1038/ncb1290
cites work	wds:Q81019228-028B6C64-8D3E-4346-8189-0EC5BEA9C6C0 wds:Q81019228-06139ACE-84D2-4BEC-92FC-D2BAD5921D66 wds:Q81019228-0CCD920F-E2EA-4C65-95FF-7F4D40D9FAB8 wds:Q81019228-0FB65D25-B6C5-4317-B559-0C83D1FD6658 wds:Q81019228-16011BE2-BD89-4168-9A03-BFB796DD511D wds:Q81019228-18D651E3-0051-433C-AEC9-0BF54864A49A wds:Q81019228-1D6535F9-3732-41F3-BED0-8F43979CEDF3 wds:Q81019228-30AEC5F5-2578-4287-B052-CDF1479289C0 wds:Q81019228-3EEE4E8D-1D07-47AE-8993-1C9EB86BB280 wds:Q81019228-441F33B2-BB4C-4246-A27F-47D4489C3222 wds:Q81019228-447729A5-9253-4553-8A4D-365B39BEF309 wds:Q81019228-461EEF81-F4AB-4328-B005-32C033D6C312 wds:Q81019228-52F7BD46-3B08-4367-96C8-3002BB19321B wds:Q81019228-594D8236-2319-482F-8143-6AD251A5CD33 wds:Q81019228-5FEFEE96-BE44-4DB3-883A-346368E24981 wds:Q81019228-629077A9-51B3-46BC-9FE7-F50A366AC2F7 wds:Q81019228-6C08289E-45B8-4CB8-A46A-22C45B96003F wds:Q81019228-6D5E194F-0679-49D1-ADA3-5811E2A3C28F wds:Q81019228-6EB85EA6-9F3A-495A-831B-AAC7D773C734 wds:Q81019228-71AFF7F1-A6AB-4C8E-B15D-9518C15E058B wds:Q81019228-81C200B4-4008-4CE9-A294-AF3FCC5A5B70 wds:Q81019228-82683C8E-E83B-4FAE-8543-A50C49570637 wds:Q81019228-8BC4CD3B-E0FA-4939-9FFA-66DDCC151DA9 wds:Q81019228-909CC642-FC65-4FF8-9EDB-35DD3579A87E wds:Q81019228-AF5D0F60-4B05-4BB0-8ECD-F492E4034E4A wds:Q81019228-B1E07B9C-566B-4F76-B128-C09C87A4E540 wds:Q81019228-B2960F8C-ED74-4E3D-A034-79805E2C9B63 wds:Q81019228-BC8D6EEC-94EA-494A-B018-220493715AE4 wds:Q81019228-C3C4EEB4-4105-40C8-85BA-EFE35E61AE32 wds:Q81019228-DD575139-70DD-4490-B616-9D8C4D3B2286 wds:Q81019228-EED3A222-6473-4150-AB62-BBF646895E36 wds:Q81019228-F4F604EB-6060-4B5C-BE12-06F8592D0AF9 wds:Q81019228-F9B8C835-DE1A-4271-8C8F-F3685AF0B929
cites work	A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function Structure, exchange determinants, and family-wide rab specificity of the tandem helical bundle and Vps9 domains of Rabex-5. The targeting of Lamp1 to lysosomes is dependent on the spacing of its cytoplasmic tail tyrosine sorting motif relative to the membrane Sec2p mediates nucleotide exchange on Sec4p and is involved in polarized delivery of post-Golgi vesicles Oligomeric complexes link Rab5 effectors with NSF and drive membrane fusion via interactions between EEA1 and syntaxin 13 Role of LBPA and Alix in multivesicular liposome formation and endosome organization The Rab5 effector EEA1 is a core component of endosome docking Identification of Rab GTPase-activating protein-like protein (RabGAPLP) as a novel Alix/AIP1-interacting protein Rab5 is a signalling GTPase involved in actin remodelling by receptor tyrosine kinases Golgins in the structure and dynamics of the Golgi apparatus Two new members of a family of Ypt/Rab GTPase activating proteins. Promiscuity of substrate recognition Identification of the catalytic domains and their functionally critical arginine residues of two yeast GTPase-activating proteins specific for Ypt/Rab transport GTPases The Eps8 protein coordinates EGF receptor signalling through Rac and trafficking through Rab5 Organelle identity and the targeting of peripheral membrane proteins Sequential roles for phosphatidylinositol 3-phosphate and Rab5 in tethering and fusion of early endosomes via their interaction with EEA1 Rab proteins as membrane organizers Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis A yeast GTPase-activating protein that interacts specifically with a member of the Ypt/Rab family Confirmation of the arginine-finger hypothesis for the GAP-stimulated GTP-hydrolysis reaction of Ras GTPase activity of Rab5 acts as a timer for endocytic membrane fusion Lysosome associated membrane protein 1 (Lamp1) traffics directly from the TGN to early endosomes Structure of Rab GDP-dissociation inhibitor in complex with prenylated YPT1 GTPase The guanine nucleotide-binding switch in three dimensions Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis Yip3 catalyses the dissociation of endosomal Rab–GDI complexes Targeting Rab GTPases to distinct membrane compartments The FYVE domain of early endosome antigen 1 is required for both phosphatidylinositol 3-phosphate and Rab5 binding. Critical role of this dual interaction for endosomal localization Selective membrane recruitment of EEA1 suggests a role in directional transport of clathrin-coated vesicles to early endosomes Crystal structure of the GAP domain of Gyp1p: first insights into interaction with Ypt/Rab proteins Purification and properties of a GTPase-activating protein for yeast Rab GTPases MAP, a protein interacting with a tumor suppressor, merlin, through the run domain. Small GTP-binding proteins in human endothelial cells GTP hydrolysis is not important for Ypt1 GTPase function in vesicular transport
author name string	wds:Q81019228-4E891155-C37E-4D9D-B832-242992C6A092 wds:Q81019228-8D2227C3-D024-4EC7-A5B3-0CCDE8195D90 wds:Q81019228-DBE08702-0D26-448C-839D-8B999A35EA38
author name string	Alexander K Haas Evelyn Fuchs Robert Kopajtich
rdfs:label	A GTPase-activating protein controls Rab5 function in endocytic trafficking (en) A GTPase-activating protein controls Rab5 function in endocytic trafficking (nl)
skos:prefLabel	A GTPase-activating protein controls Rab5 function in endocytic trafficking (en) A GTPase-activating protein controls Rab5 function in endocytic trafficking (nl)
name	A GTPase-activating protein controls Rab5 function in endocytic trafficking (en) A GTPase-activating protein controls Rab5 function in endocytic trafficking (nl)
author	wds:Q81019228-5BDC683C-070C-436A-A671-8BCDFEFC6988
author	Francis A. Barr
title	wds:Q81019228-86863BB9-7C09-4481-98C3-CA486097950E
title	A GTPase-activating protein controls Rab5 function in endocytic trafficking (en)
page(s)	wds:Q81019228-A027ED46-D2D3-4DCD-A232-6A83E4341170
page(s)	887-893
instance of	wds:Q81019228-08C34C67-7D42-4FD9-8A1F-FD336F59A0BD
instance of	scholarly article
PubMed ID	wds:Q81019228-ADBEAF82-1653-42F0-90F6-1A8EA238B39B
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/16086013
PubMed ID	16086013
published in	wds:Q81019228-AE08A19E-CB6F-4A36-966D-F9018766439A

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