About: Oncogenesis of multiple myeloma: 14q32 and 13q chromosomal abnormalities are not randomly distributed, but correlate with natural history, immunological features, and clinical presentation

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About: Oncogenesis of multiple myeloma: 14q32 and 13q chromosomal abnormalities are not randomly distributed, but correlate with natural history, immunological features, and clinical presentation Goto Sponge Distinct Permalink

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scientific article published on 01 March 2002

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в березні 2002 (uk) im März 2002 veröffentlichter wissenschaftlicher Artikel (de) artículu científicu espublizáu en marzu de 2002 (ast) scientific article published on 01 March 2002 (en)
publication date	wds:Q77725517-15210258-0092-4686-82C5-72F836264060
publication date	2002-03-01 00:00:00Z (xsd:dateTime)
author name string	wds:Q77725517-18A1A631-A5F3-478E-A96F-9FC05EF671B3 wds:Q77725517-28D66639-9488-4262-ADB2-1026DB4E1F10 wds:Q77725517-2B77B0E0-9121-4CD4-B327-A4D51262ED6B wds:Q77725517-698EE869-9854-457F-B24A-84194B767DE0 wds:Q77725517-84710305-ADB1-429F-9E2F-22DBADAF0DD6 wds:Q77725517-8BA9BEF1-DDA4-4C24-981A-180A87BEF42F wds:Q77725517-AB73FC54-5E22-44C8-A06D-8FE4CFCB69B3
author name string	Jean-Luc Harousseau Régis Bataille Florence Magrangeas Stéphane Minvielle Bernard Grosbois Intergroupe Francophone du Myélome Marie-José Rapp
rdfs:label	Oncogenesis of multiple myeloma: 14q32 and 13q chromosomal abnormalities are not randomly distributed, but correlate with natural history, immunological features, and clinical presentation (en) Oncogenesis of multiple myeloma: 14q32 and 13q chromosomal abnormalities are not randomly distributed, but correlate with natural history, immunological features, and clinical presentation (nl)
skos:prefLabel	Oncogenesis of multiple myeloma: 14q32 and 13q chromosomal abnormalities are not randomly distributed, but correlate with natural history, immunological features, and clinical presentation (en) Oncogenesis of multiple myeloma: 14q32 and 13q chromosomal abnormalities are not randomly distributed, but correlate with natural history, immunological features, and clinical presentation (nl)
name	Oncogenesis of multiple myeloma: 14q32 and 13q chromosomal abnormalities are not randomly distributed, but correlate with natural history, immunological features, and clinical presentation (en) Oncogenesis of multiple myeloma: 14q32 and 13q chromosomal abnormalities are not randomly distributed, but correlate with natural history, immunological features, and clinical presentation (nl)
author	wds:Q77725517-224602D3-23DD-4D4E-AE42-08CA7B430C5F wds:Q77725517-A4E58809-D50D-4396-A825-24C0D0102A69
author	Thierry Facon Herve Avet-Loiseau
title	wds:Q77725517-F9458C13-9781-4071-87C5-A599449741CC
title	Oncogenesis of multiple myeloma: 14q32 and 13q chromosomal abnormalities are not randomly distributed, but correlate with natural history, immunological features, and clinical presentation (en)
page(s)	wds:Q77725517-5BE5CB7C-F365-41D0-B3CC-3A01F8772F19
page(s)	2185-2191
instance of	wds:Q77725517-150A795A-2AD8-496A-AF61-46927C1EF91A
instance of	scholarly article
main subject	wds:Q77725517-81718DBD-DA08-49FD-A89E-ED3DF6CE02A3
main subject	multiple myeloma
PubMed ID	wds:Q77725517-E34E2416-4FE1-40A7-B9BD-8D08A46DB67C
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/11877296
PubMed ID	11877296
published in	wds:Q77725517-BF947D30-90F8-44C0-8016-0D7C35A6A2CC
published in	Blood
issue	wds:Q77725517-64C62D55-BBD4-46B7-9949-0EB535E27C7F
volume	wds:Q77725517-D8B0DAC4-5C48-4A35-A86A-7EAF57D0095D
issue	6
volume	99
DOI	wds:Q77725517-24C3CD47-0C86-4575-99ED-65DC87965E73
DOI	http://dx.doi.org/10.1182/BLOOD.V99.6.2185
DOI	10.1182/BLOOD.V99.6.2185
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q77725517
is cites work of	CD33 is expressed on plasma cells of a significant number of myeloma patients, and may represent a therapeutic target Anti-myeloma effect of homoharringtonine with concomitant targeting of the myeloma-promoting molecules, Mcl-1, XIAP, and beta-catenin Advances in understanding monoclonal gammopathy of undetermined significance as a precursor of multiple myeloma International Myeloma Working Group molecular classification of multiple myeloma: spotlight review. Cyclin D dysregulation: an early and unifying pathogenic event in multiple myeloma Loss of 1p and rearrangement of MYC are associated with progression of smouldering myeloma to myeloma: sequential analysis of a single case NEK2 induces drug resistance mainly through activation of efflux drug pumps and is associated with poor prognosis in myeloma and other cancers Integrating cytogenetics and gene expression profiling in the molecular analysis of multiple myeloma Multistep Tumorigenesis of Multiple Myeloma: Its Molecular Delineation Cytogenetic profiles in multiple myeloma and monoclonal gammopathy of undetermined significance: a study in highly purified aberrant plasma cells Prognostic and biological implications of genetic abnormalities in multiple myeloma undergoing autologous stem cell transplantation: t(4;14) is the most relevant adverse prognostic factor, whereas RB deletion as a unique abnormality is not associated Multiple myeloma biology: lessons from the 5TMM models Targeting EZH2 and PRC2 dependence as novel anticancer therapy Genetic events in the pathogenesis of multiple myeloma Deletion of chromosome 13 detected by conventional cytogenetics is a critical prognostic factor in myeloma Critical roles for immunoglobulin translocations and cyclin D dysregulation in multiple myeloma Staging and prognostication of multiple myeloma Chromothripsis identifies a rare and aggressive entity among newly diagnosed multiple myeloma patients Genomic vulnerability to LINE-1 hypomethylation is a potential determinant of the clinicogenetic features of multiple myeloma. Progress in myeloma stem cells The t(14;20) is a poor prognostic factor in myeloma but is associated with long-term stable disease in monoclonal gammopathies of undetermined significance Heterogeneous pattern of chromosomal breakpoints involving the MYC locus in multiple myeloma. The level of TACI gene expression in myeloma cells is associated with a signature of microenvironment dependence versus a plasmablastic signature A new MAFia in cancer. Chromosome abnormalities clustering and its implications for pathogenesis and prognosis in myeloma Overexpression of transcripts originating from the MMSET locus characterizes all t(4;14)(p16;q32)-positive multiple myeloma patients Monoclonal gammopathy of undetermined significance and smoldering multiple myeloma: a review of the current understanding of epidemiology, biology, risk stratification, and management of myeloma precursor disease High incidence of trisomies 1q, 9q, and 11q in multiple myeloma: results from a comprehensive molecular cytogenetic analysis Duplication of chromosome arms 9q and 11q: evidence for a novel, 14q32 translocation-independent pathogenetic pathway in multiple myeloma Molecular aspects of multiple myeloma Further cytogenetic characterization of multiple myeloma confirms that 14q32 translocations are a very rare event in hyperdiploid cases Ploidy, as detected by fluorescence in situ hybridization, defines different subgroups in multiple myeloma Prognostic significance of copy-number alterations in multiple myeloma A practical approach to the detection of prognostically significant genomic aberrations in multiple myeloma Global Gene Expression Profiling in the Study of Multiple Myeloma Age has a profound effect on the incidence and significance of chromosome abnormalities in myeloma Characterization of oncogene dysregulation in multiple myeloma by combined FISH and DNA microarray analyses t(11;14) and t(4;14) translocations correlated with mature lymphoplasmacytoid and immature morphology, respectively, in multiple myeloma Smoldering (asymptomatic) multiple myeloma: revisiting the clinical dilemma and looking into the future. IgD myeloma indicated by plasma cells in the peripheral blood and massive pleural effusion Impact of genetic abnormalities on the prognoses and clinical parameters of patients with multiple myeloma Analysis of signal transducer and activator of transcription 3 (Stat 3) pathway in multiple myeloma: Stat 3 activation and cyclin D1 dysregulation are mutually exclusive events Prognostic value and efficacy evaluation of novel drugs for cytogenetic aberrations in multiple myeloma: a meta-analysis. Timing of acquisition of deletion 13 in plasma cell dyscrasias is dependent on genetic context Novel regulation of nuclear factor-YB by miR-485-3p affects the expression of DNA topoisomerase IIα and drug responsiveness Minor clone provides a reservoir for relapse in multiple myeloma Multiple myeloma: comparison of two dose-intensive melphalan regimens (100 vs 200 mg/m(2))

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