About: Inhibition of cholesterol synthesis and hepatic 3-hydroxy-3-methylglutaryl--CoA reductase in rats by simvastatin and pravastatin

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About: Inhibition of cholesterol synthesis and hepatic 3-hydroxy-3-methylglutaryl--CoA reductase in rats by simvastatin and pravastatin Goto Sponge Distinct Permalink

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scientific article published on 01 November 1995

Attributes	Values
rdf:type	Item
description	wetenschappelijk artikel (nl) наукова стаття, опублікована в листопаді 1995 (uk) article scientifique publié en 1995 (fr) im November 1995 veröffentlichter wissenschaftlicher Artikel (de) scientific article published on 01 November 1995 (en) artículu científicu espublizáu en payares de 1995 (ast)
publication date	wds:Q70919515-8FFB993B-3D3A-40FC-9990-59AAE39963BB
publication date	1995-11-01 00:00:00Z (xsd:dateTime)
exact match	wds:Q70919515-E30A7D34-308A-4122-ADDB-C36C1C6148C4
exact match	https://scigraph.springernature.com/pub.10.1007/bf02536292
cites work	wds:Q70919515-00D3AD11-7DA2-4ACB-A602-7FCD5ED57E58 wds:Q70919515-06ECF9A4-5ACC-492E-8096-8C41A1834082 wds:Q70919515-10E658CF-B4E7-4EA5-A568-5C83D4A4B54D wds:Q70919515-17706226-5819-42F9-8B87-5A225DAB321D wds:Q70919515-1AD71D30-04C1-4C5E-94FB-6AD67A2C4E28 wds:Q70919515-351E9E5F-7F84-4E4E-97E3-634E4D5A8200 wds:Q70919515-4A18EAA5-53E6-46D4-9548-3BD554BBFDA1 wds:Q70919515-78A3804A-4403-4AA2-B353-BC18429C6B7A wds:Q70919515-8777ECD7-D480-4715-973A-0F9ECCE3B8FD wds:Q70919515-9201B090-4E91-418C-9401-74482C9646F7 wds:Q70919515-96FD01E8-9A51-4282-BEEC-5326516B0CDD wds:Q70919515-A348970F-3536-4308-A18D-3DEDAC4A0A51 wds:Q70919515-A34F07EA-6BFD-4B93-80BE-298EB2627A59 wds:Q70919515-B034E74A-6954-4281-8B05-912A144B6590 wds:Q70919515-B7F38EC1-A9F1-4C04-96F7-03DEF1713A9B wds:Q70919515-C675A64E-D6E6-4118-B689-4914B7FB68FA wds:Q70919515-F7C81637-AC14-43EB-9F80-CF02488832CB wds:Q70919515-F9BDE85F-B9F0-44D5-A539-E7420A12308E
cites work	Mevinolin, an inhibitor of cholesterol synthesis, induces mRNA for low density lipoprotein receptor in livers of hamsters and rabbits Metabolic disposition studies on simvastatin, a cholesterol-lowering prodrug Tissue selectivity of the cholesterol-lowering agents lovastatin, simvastatin and pravastatin in rats in vivo A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Clinical pharmacokinetics and practical applications of simvastatin Determination of mevalonate in blood plasma in man and rat. Mevalonate "tolerance" tests in man Mode of interaction of beta-hydroxy-beta-methylglutaryl coenzyme A reductase with strong binding inhibitors: compactin and related compounds Measurement of mevalonate in human plasma and urine by multiple selected ion monitoring Determination of the HMG-CoA reductase inhibitors simvastatin, lovastatin, and pravastatin in plasma by gas chromatography/chemical ionization mass spectrometry Comparative effects of simvastatin (MK-733) and pravastatin (CS-514) on hypercholesterolemia induced by cholesterol feeding in rabbits Mevalonic acid in human plasma: relationship of concentration and circadian rhythm to cholesterol synthesis rates in man Tissue selectivity of pravastatin sodium, lovastatin and simvastatin. The relationship between inhibition of de novo sterol synthesis and active drug concentrations in the liver, spleen and testis in rat The effect of cholestyramine on liver HMG-CoA reductase and cholesterol 7 alpha-hydroxylase in various laboratory animals Evaluation of enzyme activities by gas chromatography-mass spectrometry: HMGCoA reductase and cholesterol 7 alpha-hydroxylase A simple model for studies on the regulation of cholesterol synthesis using freshly isolated hepatocytes Pantethine inhibits cholesterol and fatty acid syntheses and stimulates carbon dioxide formation in isolated rat hepatocytes. Carrier-mediated uptake of pravastatin by rat hepatocytes in primary culture Drugs inhibiting HMG-CoA reductase
author name string	wds:Q70919515-0632E4CC-5403-44CC-A40E-D6A505B8C484 wds:Q70919515-703252CD-D859-4C9D-B83B-54413CB96420 wds:Q70919515-88652EF0-F59C-47A3-8FE1-CD7EB2FE9A59
author name string	M Del Puppo M Galli Kienle S Rauli
rdfs:label	Inhibition of cholesterol synthesis and hepatic 3-hydroxy-3-methylglutaryl--CoA reductase in rats by simvastatin and pravastatin (en) Inhibition of cholesterol synthesis and hepatic 3-hydroxy-3-methylglutaryl--CoA reductase in rats by simvastatin and pravastatin (nl)
skos:prefLabel	Inhibition of cholesterol synthesis and hepatic 3-hydroxy-3-methylglutaryl--CoA reductase in rats by simvastatin and pravastatin (en) Inhibition of cholesterol synthesis and hepatic 3-hydroxy-3-methylglutaryl--CoA reductase in rats by simvastatin and pravastatin (nl)
name	Inhibition of cholesterol synthesis and hepatic 3-hydroxy-3-methylglutaryl--CoA reductase in rats by simvastatin and pravastatin (en) Inhibition of cholesterol synthesis and hepatic 3-hydroxy-3-methylglutaryl--CoA reductase in rats by simvastatin and pravastatin (nl)
title	wds:Q70919515-70BDF9E2-F420-432E-BC5A-6F2469053BF0
title	Inhibition of cholesterol synthesis and hepatic 3-hydroxy-3-methylglutaryl--CoA reductase in rats by simvastatin and pravastatin (en)
page(s)	wds:Q70919515-F9C55568-B8D2-4558-836E-625F711E43FF
page(s)	1057-1061
instance of	wds:Q70919515-3DF4543D-4996-40DF-AD6B-C436BC669E1F
instance of	scholarly article
main subject	wds:Q70919515-06943343-A394-4F2A-8653-0F665EA119FA
main subject	simvastatin
PubMed ID	wds:Q70919515-189FFA5A-2862-4A9B-87DA-52188ECADC3D
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/8569435
PubMed ID	8569435
published in	wds:Q70919515-2274BC3D-CB9A-4782-B825-1E06BE15F634
published in	Lipids
issue	wds:Q70919515-7248D685-9F76-4406-A651-2F89960E9B55
volume	wds:Q70919515-68347758-4DC5-452C-BC90-100B5297EAD7
issue	11
volume	30
DOI	wds:Q70919515-BF9613AB-4BD9-4282-BAFE-92EAEA244296
DOI	http://dx.doi.org/10.1007/BF02536292
DOI	10.1007/BF02536292
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q70919515
is cites work of	Cholesterol-lowering properties of Ganoderma lucidum in vitro, ex vivo, and in hamsters and minipigs Atorvastatin and simvastatin have distinct effects on hydroxy methylglutaryl-CoA reductase activity and mRNA abundance in the guinea pig Radiation as a risk factor for cardiovascular disease 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) induce hepatic expression of the phospholipid translocase mdr2 in rats Chemoprevention by pravastatin, a 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, of N-methyl-N-nitrosourea-induced colon carcinogenesis in F344 rats. Simvastatin mitigates increases in risk factors for and the occurrence of cardiac disease following 10 Gy total body irradiation. Prevention of radiation-induced mammary tumors Sprouty2 loss-induced IL6 drives castration-resistant prostate cancer through scavenger receptor B1.
is cites work of	wds:Q24804269-CFB3C96E-C3C2-41A5-9487-9FA68A2DBCD4 wds:Q28580203-B0BA0F25-4616-4251-949C-E0CF2556DA82 wds:Q54982147-78C6B177-B2BA-40A2-9FA0-D808DD054741 wds:Q35822374-EB306C09-DE12-4E6F-848E-564CD8FDE999 wds:Q53452219-B03F42BC-0310-4F4B-AC31-024A4586A778 wds:Q28369437-C6B9D38A-8C71-454A-A4F6-7191CE3C4DBA wds:Q34484842-82073DAF-862A-4A87-B247-43CFEE3FCEF1 wds:Q34150728-3121FE06-4FD3-436C-88B8-C05218FE86FC

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