About: Smurf1 inhibits osteoblast differentiation and bone formation in vitro and in vivo

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About: Smurf1 inhibits osteoblast differentiation and bone formation in vitro and in vivo Goto Sponge Distinct Permalink

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scientific article published on 29 December 2003

Attributes	Values
rdf:type	Item
description	videnskabelig artikel (da) article científic (ca) articolo scientifico (it) artigo científico (pt) bilimsel makale (tr) vedecký článok (sk) vetenskaplig artikel (sv) vědecký článek (cs) wetenschappelijk artikel (nl) wissenschaftlicher Artikel (de) научни чланак (sr) article scientifique (fr) artículu científicu espublizáu en 2003 (ast) наукова стаття, опублікована в грудні 2003 (uk) مقالة علمية نشرت في 29 ديسمبر 2003 (ar) scientific article published on 29 December 2003 (en)
publication date	wds:Q37113932-8F3E68F2-A161-4A71-9D85-4C2839682BF6
publication date	2003-12-29 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q37113932-F5DB2AD0-03C3-435D-9C90-564BCD4FE3C7
language of work or name	English
cites work	wds:Q37113932-1BFEAA06-1522-4BAF-B2C4-44E3EF2FAB85 wds:Q37113932-2A2C58F7-069E-40E4-8A73-7D4A2FEB81F7 wds:Q37113932-2A9E0EEE-5D67-4754-9C2A-9B82E98F29C2 wds:Q37113932-30CF396E-2646-4416-BB4A-4D356EFE9F80 wds:Q37113932-33351F35-5104-415C-A3C6-A5986BA7FC16 wds:Q37113932-4B454BAC-1318-47EE-89BA-B55DF51D45D0 wds:Q37113932-547984C7-A887-4D31-88AF-8FB29917B88F wds:Q37113932-6C8D9A51-8ED2-4A84-8495-8EF505DD0A63 wds:Q37113932-71455AF0-50FD-4BA2-8E73-5A1DC524D04C wds:Q37113932-715F7458-46E0-4FB8-A71C-A74C47B4E5C0 wds:Q37113932-75028875-EC7C-499E-9DC5-5AA91AC1F1DD wds:Q37113932-7797E55F-37AA-4D3A-A518-0215B6DEF1D6 wds:Q37113932-78C85ACD-F1A0-442A-A094-C4F976A9A515 wds:Q37113932-7A44D67E-7EEC-445A-A985-7BC5A431CACD wds:Q37113932-83D69038-BAA2-4078-83DD-74A57A8B9E3E wds:Q37113932-86D9F1E8-100C-40CF-87C5-38BF2E420797 wds:Q37113932-894B5658-28F4-46E3-8FF4-D955F884DD41 wds:Q37113932-8BE92454-032E-4442-9EFE-13A8AB9C53A1 wds:Q37113932-8FB9E8AB-DD7B-4803-8BEE-214EC0020D24 wds:Q37113932-A72B1EA7-A67F-4F86-A8D8-BE1B3EE71492 wds:Q37113932-AD8ECDC1-6507-49FE-B3B0-DD5DB419A6AC wds:Q37113932-B5AE3130-91CF-426E-85F1-B29C9A86405E wds:Q37113932-C206E798-27AB-4A6E-808A-D7ACD97FDE65 wds:Q37113932-C355E0CB-ACF2-4E1A-8905-CF9A2ACC34B9 wds:Q37113932-C44D47D0-1CD5-4A14-AFE9-4C43C576AF30 wds:Q37113932-D79C1ED9-165C-408E-8E11-8749F201CE1F wds:Q37113932-E8FFADE1-B2EF-4605-9F97-9470BD655F9F wds:Q37113932-F9327EE2-546B-4E93-9BC2-4590EBC089A9
cites work	Novel regulators of bone formation: molecular clones and activities Differential roles for bone morphogenetic protein (BMP) receptor type IB and IA in differentiation and specification of mesenchymal precursor cells to osteoblast and adipocyte lineages NF-kappaB specifically activates BMP-2 gene expression in growth plate chondrocytes in vivo and in a chondrocyte cell line in vitro TGF-beta induces assembly of a Smad2-Smurf2 ubiquitin ligase complex that targets SnoN for degradation Bone morphogenetic protein and bone morphogenetic protein gene family in bone formation and repair Ubiquitin-mediated proteolysis: biological regulation via destruction Ubiquitin: Roles in protein modification and breakdown The DSmurf ubiquitin-protein ligase restricts BMP signaling spatially and temporally during Drosophila embryogenesis. Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signaling A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation Themes and variations on ubiquitylation The ubiquitin system Disruption of transforming growth factor beta signaling by a mutation that prevents transphosphorylation within the receptor complex. Structural basis of BMP signalling inhibition by the cystine knot protein Noggin Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos Selective inhibitors of the osteoblast proteasome stimulate bone formation in vivo and in vitro E3 Ubiquitin Ligase Smurf1 Mediates Core-binding Factor α1/Runx2 Degradation and Plays A Specific Role in Osteoblast Differentiation Osteocyte control of bone formation via sclerostin, a novel BMP antagonist Sclerostin is a novel secreted osteoclast-derived bone morphogenetic protein antagonist with unique ligand specificity Smurf1 regulates the inhibitory activity of Smad7 by targeting Smad7 to the plasma membrane Separate cis-acting DNA elements of the mouse pro-alpha 1(I) collagen promoter direct expression of reporter genes to different type I collagen-producing cells in transgenic mice Bone morphogenetic protein receptor signaling is necessary for normal murine postnatal bone formation Skeletal Overexpression of Noggin Results in Osteopenia and Reduced Bone Formation Smurf1 facilitates myogenic differentiation and antagonizes the bone morphogenetic protein-2-induced osteoblast conversion by targeting Smad5 for degradation Cooperative inhibition of bone morphogenetic protein signaling by Smurf1 and inhibitory Smads
author name string	wds:Q37113932-16B0883D-A0BF-4840-8822-818BE8C407D1 wds:Q37113932-25A898EE-A1CC-46E9-9099-F612384125C0 wds:Q37113932-588FF192-AC5A-4382-BC75-E62572EDF0B3 wds:Q37113932-6F76A335-4F2A-4ADC-ABD2-AF822720723B wds:Q37113932-78FECC52-97F1-4597-AF2A-C9204CF6C322 wds:Q37113932-7A9B1F93-A083-478F-82C7-DE0A8CF0C081
author name string	Ming Zhao Di Chen Stephen E Harris Babatunde O Oyajobi Gregory R Mundy Mei Qiao
rdfs:label	Smurf1 inhibits osteoblast differentiation and bone formation in vitro and in vivo (en) Smurf1 inhibits osteoblast differentiation and bone formation in vitro and in vivo (nl) Smurf1 inhibits osteoblast differentiation and bone formation in vitro and in vivo (ast)
skos:prefLabel	Smurf1 inhibits osteoblast differentiation and bone formation in vitro and in vivo (en) Smurf1 inhibits osteoblast differentiation and bone formation in vitro and in vivo (nl) Smurf1 inhibits osteoblast differentiation and bone formation in vitro and in vivo (ast)
name	Smurf1 inhibits osteoblast differentiation and bone formation in vitro and in vivo (en) Smurf1 inhibits osteoblast differentiation and bone formation in vitro and in vivo (nl) Smurf1 inhibits osteoblast differentiation and bone formation in vitro and in vivo (ast)
title	wds:Q37113932-ADFFAA10-CF3E-4A0E-AE87-5EBC58F1F5D1
title	Smurf1 inhibits osteoblast differentiation and bone formation in vitro and in vivo (en)

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