About: Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase

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About: Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase Goto Sponge Distinct Permalink

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rdf:type	Item
description	wissenschaftlicher Artikel (de) artículu científicu espublizáu en 1998 (ast) vědecký článek publikovaný v roce 1998 (cs) vedecký článok (publikovaný 1998/11/01) (sk) مقالة علمية (نشرت في نوفمبر 1998) (ar) 1998 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած (hyw) наукова стаття, опублікована в листопаді 1998 (uk) 1998 թվականի նոյեմբերին հրատարակված գիտական հոդված (hy) scientific journal article (en) wetenschappelijk artikel (gepubliceerd op 1998/11/01) (nl)
publication date	wds:Q28613291-76444075-A2D0-4053-AF68-A58486840CA3
publication date	1998-11-01 00:00:00Z (xsd:dateTime)
cites work	wds:Q28613291-028A497F-33E3-49C6-A0AF-3B4334B7C9A3 wds:Q28613291-08578738-D734-4B88-ADC9-69E0E9774C64 wds:Q28613291-0D69BAC9-D2CD-4583-99D9-ADF24DAF0B98 wds:Q28613291-41FCC9FB-6E2B-425F-B694-DD4AB8C231C5 wds:Q28613291-5326A656-649F-491C-B70D-8767A6449783 wds:Q28613291-56C0DE3E-C0E5-44BB-BBE7-C6FA583A4E3F wds:Q28613291-592C82B3-70F8-4CCF-BAD7-5E84E2A879F9 wds:Q28613291-5A4675B4-3F9E-45A1-91F5-3E36752ACB53 wds:Q28613291-72503CD9-4581-43AA-B425-E65022161C07 wds:Q28613291-74EA2A94-D7A6-4D02-AD82-18AFDB89C0E4 wds:Q28613291-77837817-883C-4A9A-B7AB-D4D14B12A5C6 wds:Q28613291-785CB75F-A6AD-4077-8432-F2685919FCC2 wds:Q28613291-809DB332-9622-4B49-ACB0-2946951EEA43 wds:Q28613291-813E34DC-4FA4-489D-9DA3-B9B9435A2130 wds:Q28613291-83D3DCE5-1E86-4BD4-935F-2C85921B8F2A wds:Q28613291-86D5BA4B-748C-4AA4-BA06-1E8F0BF925B9 wds:Q28613291-9EE2A886-2D6E-4B82-9034-A058761FF735 wds:Q28613291-B12A876D-4F1E-4997-A38A-2A8841DF0C76 wds:Q28613291-BBDB30BE-FED9-476F-920D-B7E37ABF4AF4 wds:Q28613291-BD5412F4-64CD-48CE-8F68-629CD98EA84A wds:Q28613291-D9B123B6-700F-42FD-9E68-52E037743168 wds:Q28613291-DD540FD0-F1CC-4AF4-9C10-6CF3F4A648A1 wds:Q28613291-F36B6E60-DF0B-41A7-94D2-2593EECA0FBF wds:Q28613291-FF175729-5107-4A3E-9BFF-2AB6FCD9BF10
cites work	The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases WAF1, a potential mediator of p53 tumor suppression Cdc2 regulatory factors Apoptosis in cancer therapy: crossing the threshold Cdc2 protein kinase is complexed with both cyclin A and B: evidence for proteolytic inactivation of MPF Nuclear accumulation of p21Cip1 at the onset of mitosis: a role at the G2/M-phase transition Transcriptional repression of the neu protooncogene by the adenovirus 5 E1A gene products Distinct roles for cyclin-dependent kinases in cell cycle control Suppression of apoptosis by dominant negative mutants of cyclin-dependent protein kinases Mechanism of action of taxol Loss of normal p53 function confers sensitization to Taxol by increasing G2/M arrest and apoptosis Cell-cycle control and its watchman. Cdk2 kinase is required for entry into mitosis as a positive regulator of Cdc2-cyclin B kinase activity Inhibition of cyclin-dependent kinases by purine analogues. Features of apoptotic cells measured by flow cytometry Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication Involvement of p21 in mitotic exit after paclitaxel treatment in MCF-7 breast adenocarcinoma cell line Antibodies stage a comeback in cancer treatment. Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21 Systemic gene therapy with p53 reduces growth and metastases of a malignant human breast cancer in nude mice Shared actions of endotoxin and taxol on TNF receptors and TNF release The control of apoptosis in mammalian cells Deletion of p21 cannot substitute for p53 loss in rescue of mdm2 null lethality
author name string	wds:Q28613291-09A503DD-AB03-4EAE-AF74-1B2A50C74520 wds:Q28613291-35CF570F-69EF-45E5-8D40-2C2304246019 wds:Q28613291-5952510C-4BAD-4283-B9B4-E9BBF6788ED9 wds:Q28613291-83A27DAD-8087-4F7B-90B7-33944ADE375E wds:Q28613291-944CD427-DF66-4B5F-9105-3663321AE818 wds:Q28613291-DE1057CD-B6D3-42BE-912E-262A3F2C7FF8
author name string	B Liu J Yao T J McDonnell D Yu M C Hung T Jing
rdfs:label	Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase (en) Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase (nl) Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase (ast)
skos:prefLabel	Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase (en) Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase (nl) Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase (ast)
name	Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase (en) Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase (nl) Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase (ast)
author	wds:Q28613291-6BE2CC2B-C0E9-4C16-9C0E-8BC771BBF5F2
author	Ming Tan
title	wds:Q28613291-0CFEE7C6-364E-44DF-8D8F-971D400BEF5E
title	Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase (en)
page(s)	wds:Q28613291-F300275A-786F-49B8-9957-0345416121A9
page(s)	581-591
instance of	wds:Q28613291-530D644C-D6C1-435A-8D59-40A682481BB2
instance of	scholarly article
main subject	wds:Q28613291-689D0F20-1A6D-48D9-BCA0-0BF838EEC075 wds:Q28613291-CC610ABF-5AB6-4FF2-BAA2-68D87494EDB3
main subject	apoptotic process overexpression
PubMed ID	wds:Q28613291-DE288CB7-DC37-4D29-BAAE-59DD70ABDFC4
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/9844631
PubMed ID	9844631
published in	wds:Q28613291-B35067E1-5CBD-40D4-B04B-5976857A675A
published in	Molecular Cell
issue	wds:Q28613291-258CE804-0500-4224-9CAA-6A0C4D581506

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