About: Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation

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About: Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation Goto Sponge Distinct Permalink

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scientific journal article

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rdf:type	Item
description	articolo scientifico (it) artículu científicu espublizáu en 1997 (ast) vědecký článek publikovaný v roce 1997 (cs) наукова стаття, опублікована в грудні 1997 (uk) 1997 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած (hyw) 1997 թվականի դեկտեմբերին հրատարակված գիտական հոդված (hy) مقالة علمية (نشرت في ديسمبر 1997) (ar) vedecký článok (publikovaný 1997/12/01) (sk) article scientifique publié en 1997 (fr) wetenschappelijk artikel (gepubliceerd op 1997/12/01) (nl) scientific journal article (en) im Dezember 1997 veröffentlichter wissenschaftlicher Artikel (de)
publication date	wds:Q28586360-04009145-6B21-438A-882C-7C229FFD71BB
publication date	1997-12-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28586360-910A84F2-1610-4FE3-84B2-08152E0EB9D3
language of work or name	English
exact match	wds:Q28586360-7E04915F-A4B9-490D-9EFE-4B92A085074E
exact match	https://scigraph.springernature.com/pub.10.1038/ng1297-423
cites work	wds:Q28586360-017F072C-592E-4104-896E-546D786CB45C wds:Q28586360-1ED3BE0D-32B5-4681-83CD-94CBA4CEC9ED wds:Q28586360-2506CFF0-29FD-4A06-8031-40AC28B3C364 wds:Q28586360-2E7405DB-AF2E-4745-B6BF-2D0EC5C2B32B wds:Q28586360-2F389FE5-4669-44FD-B059-6F2A8227D093 wds:Q28586360-403BE35B-D840-4987-85F7-7B60B7BEB639 wds:Q28586360-4581D8DA-C879-4939-86EB-37F3935BA775 wds:Q28586360-51703E29-090E-40D8-909B-0CC742B76EE1 wds:Q28586360-53553982-5877-4F95-8652-B645FE630A5C wds:Q28586360-53B5B994-ECBF-4BD7-B40D-3EEC35B21DAC wds:Q28586360-5B60A2E0-FFBD-4FBE-A800-0702A3472596 wds:Q28586360-5FB161E2-C934-4F38-873C-E0D23A0AF6FD wds:Q28586360-63CA8BE4-B4C3-4D9F-B047-4A233D07B9BE wds:Q28586360-69DC2B11-A36F-4A79-B2F0-46A151AAC0C0 wds:Q28586360-763ACE7F-77D9-4F19-B265-70E21348D580 wds:Q28586360-8BEB93CF-F64C-4C32-B098-F3F78B034C60 wds:Q28586360-91FC589F-3B72-4F19-9AC9-3BB63F6BFBC0 wds:Q28586360-922282FF-EF04-4C61-8BF6-D57ABB547C70 wds:Q28586360-9487C17A-DA72-46DB-B2E6-9381E8784D80 wds:Q28586360-9AD676B1-9310-4C93-9BDF-42145530332A wds:Q28586360-9C1FB59F-662B-4D42-94E2-3FF0780AFF76 wds:Q28586360-9E77F7A5-8650-48F9-8B16-B6E0F77D0C29 wds:Q28586360-A34C1E53-BD76-410F-93C2-15FB645F467A wds:Q28586360-A9BBBB86-98E0-410E-9E82-4DCDAE2108EE wds:Q28586360-B0C7B121-7C04-4030-B102-59A3ED60AF02 wds:Q28586360-B3BA28D9-CE0C-4975-9F04-9336AE885BCE wds:Q28586360-B8AFC495-8DF1-438B-BA9C-D05D288D39B7 wds:Q28586360-BBB5B76A-76F0-4337-B5BE-7D41109F410D wds:Q28586360-C20BA4E8-27B5-4799-9E0F-E8351F3ABE62 wds:Q28586360-C8496D1F-C547-4DAB-BABB-04290E35C668 wds:Q28586360-C973890E-F7F1-48E5-B284-B9093F2C5FAF wds:Q28586360-CAB365A0-68E5-44AB-8FE0-280A241BD979 wds:Q28586360-CC6D63C2-958F-4A3B-9660-76A3D49996BA wds:Q28586360-CC8A1FB1-E2E1-4D28-96FF-8CBBB42360E8 wds:Q28586360-D27C6D04-A401-4BA7-8B13-A10C7F5F9588 wds:Q28586360-D35BF768-5747-490C-BA66-FAB626FA669D wds:Q28586360-D9D8C746-FFE9-4F1D-BEAD-E2010D369342 wds:Q28586360-E6CC5D41-3027-46AC-85AB-79FF70D59195 wds:Q28586360-E991D740-653E-43F7-8F3A-1925ACB32549 wds:Q28586360-EBC5F23D-2580-4FF9-9B3C-E371B936E94D wds:Q28586360-F046CA25-6606-4804-845B-9323CE497911 wds:Q28586360-F294D17F-E042-4A83-9E3F-3BE52A59E657 wds:Q28586360-FAE2D4E1-8473-4F64-B9FE-9CBA08C2263F wds:Q28586360-FCAB6F09-B6D5-4058-994B-7DCEF5B4C4C0 wds:Q28586360-FEC9DF8B-0589-4603-8E19-042C41137D54 wds:Q28586360-FF88A484-57A4-456C-B83F-F9C291C9E10D
cites work	Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes? Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene Breast and other cancers in families with ataxia-telangiectasia Linkage of early-onset familial breast cancer to chromosome 17q21 Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13. BRCA2 mutations in primary breast and ovarian cancers BRCA1 mutations in primary breast and ovarian carcinomas. Transcriptional activation by BRCA1 Heterozygous ATM mutations do not contribute to early onset of breast cancer Variation of risks of breast and ovarian cancer associated with different germline mutations of the BRCA2 gene Inherited breast and ovarian cancer. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1 Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2 Association of BRCA1 with Rad51 in mitotic and meiotic cells Identification of the breast cancer susceptibility gene BRCA2 The BRC repeats are conserved in mammalian BRCA2 proteins Brca2 is coordinately regulated with Brca1 during proliferation and differentiation in mammary epithelial cells The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds Double indemnity: p53, BRCA and cancer. p53 mutation partially rescues developmental arrest in Brca1 and Brca2 null mice, suggesting a role for familial breast cancer genes in DNA damage repair. Internal repeats in the BRCA2 protein sequence Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53 Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53 Abnormal centrosome amplification in the absence of p53. Brca2 is required for embryonic cellular proliferation in the mouse Cancer-susceptibility genes. Gatekeepers and caretakers Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma p53 mutations in BRCA1-associated familial breast cancer Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos BRCA1 is a component of the RNA polymerase II holoenzyme The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities Inactivation of the mouse Brca1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development. A single BRCA2 mutation in male and female breast cancer families from Iceland with varied cancer phenotypes Murine Brca2: sequence, map position, and expression pattern.

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