About: Delayed dark-adaptation and lipofuscin accumulation in abcr+/- mice: implications for involvement of ABCR in age-related macular degeneration

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About: Delayed dark-adaptation and lipofuscin accumulation in abcr+/- mice: implications for involvement of ABCR in age-related macular degeneration Goto Sponge Distinct Permalink

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rdf:type	Item
description	artículu científicu espublizáu en 2001 (ast) vědecký článek publikovaný v roce 2001 (cs) 2001 թուականի Յուլիսին հրատարակուած գիտական յօդուած (hyw) 2001 թվականի հուլիսին հրատարակված գիտական հոդված (hy) наукова стаття, опублікована в липні 2001 (uk) مقالة علمية (نشرت في يوليو 2001) (ar) vedecký článok (publikovaný 2001/07/01) (sk) wetenschappelijk artikel (gepubliceerd op 2001/07/01) (nl) im Juli 2001 veröffentlichter wissenschaftlicher Artikel (de) scientific journal article (en)
publication date	wds:Q28505587-7800EB08-B8AB-4976-8CC3-DF521A5AD6F7
publication date	2001-07-01 00:00:00Z (xsd:dateTime)
language of work or name	wds:Q28505587-F9E42867-EC1D-4B41-B2F5-0ED76A292824
language of work or name	English
author name string	wds:Q28505587-15914A9C-9C75-4E19-933A-D8E4D51A6D1B wds:Q28505587-3ACBA0AB-742B-4291-85E1-880B5463FA9A wds:Q28505587-3D57622C-AF8A-4EFD-B627-ADCD01A2BC83 wds:Q28505587-4EDD6AF4-8D23-4655-AB7E-B9862DE56BF8 wds:Q28505587-92AD360E-3941-4959-A07B-9F263226FA58 wds:Q28505587-FBB9CB4F-33B8-4BBE-85ED-E1B9D6D20A8D
author name string	J. Weng X. Liu G. H. Travis D. G. Birch N. L. Mata R. T. Tzekov
rdfs:label	Delayed dark-adaptation and lipofuscin accumulation in abcr+/- mice: implications for involvement of ABCR in age-related macular degeneration (en) Delayed dark-adaptation and lipofuscin accumulation in abcr+/- mice: implications for involvement of ABCR in age-related macular degeneration (nl) Delayed dark-adaptation and lipofuscin accumulation in abcr+/- mice: implications for involvement of ABCR in age-related macular degeneration (ast)
skos:prefLabel	Delayed dark-adaptation and lipofuscin accumulation in abcr+/- mice: implications for involvement of ABCR in age-related macular degeneration (en) Delayed dark-adaptation and lipofuscin accumulation in abcr+/- mice: implications for involvement of ABCR in age-related macular degeneration (nl) Delayed dark-adaptation and lipofuscin accumulation in abcr+/- mice: implications for involvement of ABCR in age-related macular degeneration (ast)
name	Delayed dark-adaptation and lipofuscin accumulation in abcr+/- mice: implications for involvement of ABCR in age-related macular degeneration (en) Delayed dark-adaptation and lipofuscin accumulation in abcr+/- mice: implications for involvement of ABCR in age-related macular degeneration (nl) Delayed dark-adaptation and lipofuscin accumulation in abcr+/- mice: implications for involvement of ABCR in age-related macular degeneration (ast)
title	wds:Q28505587-045B53A1-89D5-4FC6-9B22-0E6154004E61
title	Delayed dark-adaptation and lipofuscin accumulation in abcr+/- mice: implications for involvement of ABCR in age-related macular degeneration (en)
page(s)	wds:Q28505587-FE23BADA-30E8-44E0-ADA7-686B1C322999
page(s)	1685–1690
instance of	wds:Q28505587-A1F9E61A-16AD-4E66-A2FD-52B0259060D5
instance of	scholarly article
main subject	wds:Q28505587-B393D083-8B65-4DFD-9273-10A8365B4E04 wds:Q28505587-D2B00908-76B1-4BE7-8822-805148A00A74
main subject	macular degeneration ATP-binding cassette, sub-family A (ABC1), member 4
PubMed ID	wds:Q28505587-31A6B132-7CF9-42DF-921C-46EA364A7A8A
PubMed ID	http://rdf.ncbi.nlm.nih.gov/pubchem/reference/11431429
PubMed ID	11431429
published in	wds:Q28505587-F8D49DEA-83D7-49D9-93A2-9F2006CB9208
published in	Investigative Ophthalmology Visual Science
issue	wds:Q28505587-096C54A7-5113-415D-A328-81E4CEAF4FD7
volume	wds:Q28505587-B4747746-E724-4244-A77E-1C0ABF40C097
issue	8
volume	42
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q28505587
is cites work of	Classification of abnormal fundus autofluorescence patterns in the junctional zone of geographic atrophy in patients with age related macular degeneration Progressive age-related changes similar to age-related macular degeneration in a transgenic mouse model The role of the photoreceptor ABC transporter ABCA4 in lipid transport and Stargardt macular degeneration Induction of phase 2 genes by sulforaphane protects retinal pigment epithelial cells against photooxidative damage Differential phospholipid substrates and directional transport by ATP-binding cassette proteins ABCA1, ABCA7, and ABCA4 and disease-causing mutants Retinopathy in mice induced by disrupted all-trans-retinal clearance The ATP-binding cassette transporter ABCA4: structural and functional properties and role in retinal disease Lipofuscin and N-retinylidene-N-retinylethanolamine (A2E) accumulate in retinal pigment epithelium in absence of light exposure: their origin is 11-cis-retinal Diseases caused by defects in the visual cycle: retinoids as potential therapeutic agents Interaction of A2E with model membranes. Implications to the pathogenesis of age-related macular degeneration. Visual Cycle Modulation as an Approach toward Preservation of Retinal Integrity Effects of potent inhibitors of the retinoid cycle on visual function and photoreceptor protection from light damage in mice Treatment with isotretinoin inhibits lipofuscin accumulation in a mouse model of recessive Stargardt's macular degeneration Retinal carotenoids can attenuate formation of A2E in the retinal pigment epithelium Molecular pathology of age-related macular degeneration Serotype-dependent packaging of large genes in adeno-associated viral vectors results in effective gene delivery in mice. Primary amines protect against retinal degeneration in mouse models of retinopathies Effective delivery of large genes to the retina by dual AAV vectors Light exposure stimulates formation of A2E oxiranes in a mouse model of Stargardt's macular degeneration Cone photoreceptor abnormalities correlate with vision loss in patients with Stargardt disease Drug delivery to posterior intraocular tissues: third Annual ARVO/Pfizer Ophthalmics Research Institute Conference Retinol dehydrogenase (RDH12) protects photoreceptors from light-induced degeneration in mice Norbixin Protects Retinal Pigmented Epithelium Cells and Photoreceptors against A2E-Mediated Phototoxicity In Vitro and In Vivo The genetics of inherited macular dystrophies Genetic factors of age-related macular degeneration C20-D3-vitamin A slows lipofuscin accumulation and electrophysiological retinal degeneration in a mouse model of Stargardt disease Rpe65 Leu450Met variant is associated with reduced levels of the retinal pigment epithelium lipofuscin fluorophores A2E and iso-A2E. Murine ccl2/cx3cr1 deficiency results in retinal lesions mimicking human age-related macular degeneration. Accelerated accumulation of lipofuscin pigments in the RPE of a mouse model for ABCA4-mediated retinal dystrophies following Vitamin A supplementation Isolation and characterization of a retinal pigment epithelial cell fluorophore: an all-trans-retinal dimer conjugate Characterization of dihydro-A2PE: an intermediate in the A2E biosynthetic pathway ATP-binding cassette transporter ABCA4: molecular properties and role in vision and macular degeneration. Electrophysiological analysis of visual function in mutant mice. Protein misfolding and retinal degeneration Light and inherited retinal degeneration Quantitative fundus autofluorescence in mice: correlation with HPLC quantitation of RPE lipofuscin and measurement of retina outer nuclear layer thickness Photoreceptor cell degeneration in Abcr (-/-) mice Recovery of rod photoresponses in ABCR-deficient mice Cystic fibrosis transmembrane conductance regulator contributes to reacidification of alkalinized lysosomes in RPE cells Redundant and unique roles of retinol dehydrogenases in the mouse retina The spectrum of retinal phenotypes caused by mutations in the ABCA4 gene Evolution of ABCA4 proteins in vertebrates Retinal ultrastructure of murine models of dry age-related macular degeneration (AMD). Correction of the disease phenotype in the mouse model of Stargardt disease by lentiviral gene therapy

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