About: arachidonate 5-lipoxygenase activity

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An Entity of Type : wikibase:Item, within Data Space : wikidata.demo.openlinksw.com associated with source document(s)

Catalysis of the reaction: arachidonate + O2 = (6E,8Z,11Z,14Z)-(5S)-5-hydroperoxycosa-6,8,11,14-tetraenoate.

Attributes	Values
rdf:type	Item
description	moleculaire functie (nl) Catalysis of the reaction: arachidonate + O2 = (6E,8Z,11Z,14Z)-(5S)-5-hydroperoxycosa-6,8,11,14-tetraenoate. (en)
exact match	wds:Q14889547-9F1525C0-4923-4A00-A5CC-0B9E75338830 wds:Q14889547-B785C8FF-7E20-415F-A6FA-D04EC282941F
exact match	http://purl.obolibrary.org/obo/GO_0004051 https://www.rhea-db.org/rhea/32307
rdfs:label	aktivnost arahidonat 5-lipoksigenaze (sl) arachidonate 5-lipoxygenase activity (en)
skos:prefLabel	aktivnost arahidonat 5-lipoksigenaze (sl) arachidonate 5-lipoxygenase activity (en)
name	aktivnost arahidonat 5-lipoksigenaze (sl) arachidonate 5-lipoxygenase activity (en)
Gene Ontology ID	wds:Q14889547-64B96E43-8B61-4E50-8D3D-E5173301EDE8
Gene Ontology ID	GO:0004051
instance of	wds:Q14889547-A5853242-5176-46F4-9EEA-EA81E02910B2
instance of	molecular function
subclass of	wds:Q14889547-690FD8D9-950E-4416-95A7-0A314AF14F34
subclass of	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
has part(s)	wds:Q14889547-6EAE6B86-3191-404F-AFBE-A2FC2BFD84A8 wds:Q14889547-C5566459-CD12-4438-84FA-21334A15ACC1 wds:Q14889547-D454EFCA-59A7-41E3-A74F-B6302FC0DCC9 wds:Q14889547-D8CB643D-42AA-414F-A810-0FFE9D26B872
has part(s)	water dioxygen arachidonate leukotriene A4(1-)
skos:altLabel	5-delta-lipoxygenase activity (en) 5-lipoxygenase activity (en) 5Delta-lipoxygenase activity (en) GO:0004051 (en) arachidonate:oxygen 5-oxidoreductase activity (en) arachidonic 5-lipoxygenase activity (en) arachidonic acid 5-lipoxygenase activity (en) delta5-lipoxygenase activity (en) leukotriene-A4 synthase activity (en)
EC enzyme number	wds:Q14889547-AD9FD6D2-6FAD-4FA0-AECA-1CA20426100E
EC enzyme number	1.13.11.34
is about of	https://www.wikidata.org/wiki/Special:EntityData/Q14889547
is part of of	arachidonate leukotriene A4(1-)
is part of of	wds:Q27104215-8EC3B67A-21FD-448F-8EFF-2CACBF3FDF82 wds:Q27124709-3D4B1005-B9BD-42F5-A8E1-C252BD5E3C98
is main subject of	Conversion of human 5-lipoxygenase to a 15-lipoxygenase by a point mutation to mimic phosphorylation at Serine-663 Conversion of pro-inflammatory murine Alox5 into an anti-inflammatory 15S-lipoxygenating enzyme by multiple mutations of sequence determinants. The suppression of 5-lipoxygenation of arachidonic acid in human polymorphonuclear leucocytes by the 15-lipoxygenase product (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid: structure-activity relationship and mechanism of action Oxidative inactivation of human 5-lipoxygenase in phosphatidylcholine vesicles
is main subject of	wds:Q45903100-EDB7778E-8EDD-4754-9E51-13E4A2E80503 wds:Q71080572-F73F1AAA-9E04-40CC-9B21-31BAFC659F5C wds:Q27678617-3FD93498-228A-4625-B2D8-08B9BA52D02F wds:Q28378818-21A8974D-B38E-4742-ADE3-48E0C83F78B2
is molecular function of	wd:Q411791 wd:Q94234745 Arachidonate 5-lipoxygenase Arachidonate 5-lipoxygenase Arachidonate 5-lipoxygenase activating protein Arachidonate 5-lipoxygenase activating protein
is molecular function of	wds:Q94234745-9a1b5bda-4bf5-1cb5-79d1-bb1a0b928201 wds:Q21988234-83626372-3749-468D-B710-798A35FA310C wds:Q14889548-FC9498DE-F6DF-449F-A0A9-86461243E9E0 wds:Q28562888-8B9DDFA6-F4FF-440C-A920-0975894F968D wds:Q411791-B3BF0730-4EEB-4022-9758-329DA466C705 wds:Q28558027-9056035D-1B69-4626-8A94-F9D5941CD404 wds:Q28558027-E00A1DF6-5969-4359-91E9-46647BF88261

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